Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro

Autor: Zhu Xiangdong, Osan Christopher M, Binder David C, Meliton Lucille N, Muñoz Nilda M, Meliton Angelo Y, Dudek Steven M, Leff Alan R

Publikováno v: Journal of Inflammation, Vol 7, Iss 1, p 14 (2010)

Abstract Background Cytosolic gIVaPLA2 is a critical enzyme in the generation of arachidonate metabolites and in induction of β2-integrin adhesion in granulocytes. We hypothesized that gIVaPLA2 activation also is an essential downstream step for pos

Externí odkaz: https://doaj.org/article/703604e9cb3647d88574fbbf0ccc1492

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Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro.

Autor: Meliton AY; Section of Pulmonary and Critical Care Medicine, Departments of Medicine, The University of Chicago, 5841 S Maryland Avenue, MC 6026, Chicago, IL 60637, USA. nmunoz@medicine.bsd.uchicago.edu., Muñoz NM, Meliton LN, Binder DC, Osan CM, Zhu X, Dudek SM, Leff AR

Publikováno v: Journal of inflammation (London, England) [J Inflamm (Lond)] 2010 Mar 18; Vol. 7, pp. 14. Date of Electronic Publication: 2010 Mar 18.