Zobrazeno 1 - 10
of 545
pro vyhledávání: '"Osamu UKIMURA"'
Autor:
Saya Ito, Akihisa Ueno, Takashi Ueda, Ryota Ogura, Satoshi Sako, Yusuke Gabata, Junki Murashita, Hikaru Takahashi, Osamu Ukimura
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Germ cells preferentially induce apoptosis in response to DNA damage to avoid genomic mutations. Apoptosis of germ cells is closely related to cancer development and chemotherapy resistance; however, its regulatory mechanism is unclear. Here
Externí odkaz:
https://doaj.org/article/93ca41613edc421ca7ad8ce6839ede98
Autor:
Fumio Tsukuda, Toshihiro Shimizu, Kiichi Hagiwara, Yoshiyuki Kawano, Noboru Sakamoto, Shingo Itagaki, Yutaka Horiguchi, Shoji Koga, Osamu Ukimura
Publikováno v:
IJU Case Reports, Vol 7, Iss 4, Pp 313-315 (2024)
Introduction Histological outcome of the targeted focal therapy is in principle confirmed by targeted needle biopsy from the treated area in clinical trial. Herein, we report a rare case in which the MFT was followed by RARP. Case presentation A 68
Externí odkaz:
https://doaj.org/article/45c6b9438b78496090203d3e00aa9df9
Autor:
Masatomo Kaneko, Atsuko Fujihara, Tsuyoshi Iwata, Lorenzo Storino Ramacciotti, Suzanne L. Palmer, Masakatsu Oishi, Manju Aron, Giovanni E. Cacciamani, Vinay Duddalwar, Go Horiguchi, Satoshi Teramukai, Osamu Ukimura, Inderbir S. Gill, Andre Luis Abreu
Publikováno v:
International Brazilian Journal of Urology, Vol 50, Iss 3, Pp 319-334 (2024)
ABSTRACT Purpose: To create a nomogram to predict the absence of clinically significant prostate cancer (CSPCa) in males with non-suspicion multiparametric magnetic resonance imaging (mpMRI) undergoing prostate biopsy (PBx). Materials and Methods: We
Externí odkaz:
https://doaj.org/article/ce025be8e6424a0c987da596aec21c6e
Autor:
Takashi Ueda, Takumi Shiraishi, Masatsugu Miyashita, Naruhiro Kayukawa, Yusuke Gabata, Satoshi Sako, Ryota Ogura, Atsuko Fujihara, Koji Okihara, Osamu Ukimura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract The objective of this study is to compare the efficacy of apalutamide and bicalutamide in combination with androgen deprivation therapy in patients with metastatic hormone-sensitive prostate cancer (mHSPC). We retrospectively collected the d
Externí odkaz:
https://doaj.org/article/0c756791ca614426972b88ef1e9000bb
Autor:
Ryota Ogura, Saya Ito, Takashi Ueda, Yusuke Gabata, Satoshi Sako, Yuta Inoue, Takeshi Yamada, Hirotaka Konishi, Atsuko Fujihara, Osamu Ukimura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Identifying a novel method to monitor metastatic bladder cancer status at the cell-gene level could lead to earlier appropriate therapeutic intervention and better outcomes. In this study, we evaluated a practical method to monitor the cance
Externí odkaz:
https://doaj.org/article/b7c7a2d06b1c4da793cda991c69452ad
Autor:
Tsukasa Narukawa, Norihiro Aibe, Masashi Tsujimoto, Takumi Shiraishi, Takuya Kimoto, Gen Suzuki, Takashi Ueda, Atsuko Fujihara, Hideya Yamazaki, Osamu Ukimura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract SpaceOAR, a polyethylene-glycol hydrogel, reduces rectal radiation exposure during radiation therapy for prostate cancer. Previously, our group reported the modified technique of hydrogel insertion, which achieves greater separated distance
Externí odkaz:
https://doaj.org/article/31f2de78e8e14c24a18c05a327f3cf88
Autor:
Yuta Inoue, Takeshi Yamada, Atsuko Fujihara, Masatsugu Miyashita, Takumi Shiraishi, Masayoshi Okumi, Fumiya Hongo, Osamu Ukimura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Although recent clinical trials of new therapeutic agents for metastatic urothelial carcinoma have shown prolonged overall survival, there are few real-world evidence. To assess the impact of new therapeutic agents, we performed retrospectiv
Externí odkaz:
https://doaj.org/article/c2f46a37530c4964a452d98208fbdb6c
Autor:
Yumiko Saito, Keiko Taniguchi, Hiromi Ii, Mano Horinaka, Susumu Kageyama, Susumu Nakata, Osamu Ukimura, Toshiyuki Sakai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract γ-Glutamylcyclotransferase (GGCT) is highly expressed in multiple types of cancer tissues and its knockdown suppresses the growth of cancer cells in vitro and in vivo. Although GGCT is a promising target for cancer therapy, the mechanisms u
Externí odkaz:
https://doaj.org/article/636da57f22f844ebac82221b2e349830
Autor:
Yuichi Nakamura, Keisuke Tsuji, Takumi Shiraishi, Satoshi Sako, Ryota Ogura, Hideto Taga, Yuta Inoue, Munehiro Ohashi, Saya Ueda, Takeshi Yamada, Takashi Ueda, Atsuko Fujihara, Fumiya Hongo, Osamu Ukimura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract In a world that seeks precision medicine, genetic testing is gaining importance in clinical decision making. We previously reported the utility of a novel tool for longitudinally dividing core needle biopsy (CNB) tissues into two filamentous
Externí odkaz:
https://doaj.org/article/b8e5f288f6bd42f9906a0b0568d22723
Autor:
Mineyuki Kato, Go Horiguchi, Takashi Ueda, Atsuko Fujihara, Fumiya Hongo, Koji Okihara, Yoshinori Marunaka, Satoshi Teramukai, Osamu Ukimura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract To define a normal range for PSA values (ng/mL) by age and create a prediction model for prostate cancer incidence. We conducted a retrospective analysis using 263,073 observations of PSA values in Japanese men aged 18–98 years (2007–201
Externí odkaz:
https://doaj.org/article/d82d7a2e360d458b9e6a657bb7d1a158