Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Osamu Shimmi"'
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102566- (2023)
Summary: Apicobasal polarity determinants are potential tumor suppressors that have been extensively studied. However, the precise mechanisms by which their misregulation disrupts tissue homeostasis are not fully understood. Here, we present a compre
Externí odkaz:
https://doaj.org/article/7e323fcc48254f4cb091801a3f3cba20
Publikováno v:
Fly, Vol 16, Iss 1, Pp 118-127 (2022)
The Drosophila wing has been used as a model for studying tissue growth, morphogenesis and pattern formation. The wing veins of Drosophila are composed of two distinct structures, longitudinal veins and crossveins. Although positional information of
Externí odkaz:
https://doaj.org/article/c7bb6be63ec244a28045917e92c294c2
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106490- (2023)
Summary: Maintaining apicobasal polarity (ABP) is crucial for epithelial integrity and homeostasis during tissue development. Although intracellular mechanisms underlying ABP establishment have been well studied, it remains to be addressed how the AB
Externí odkaz:
https://doaj.org/article/227066295598433993e6bdac09c72f8c
Autor:
Osamu Shimmi, Esko Kankuri
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/5d2b41072b08479c88bbfa13d1b85f0b
Autor:
Yunxian Huang, Jinghua Gui, Satu-Marja Myllymäki, Kallol Roy, Tambet Tõnissoo, Marja L. Mikkola, Osamu Shimmi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Epithelial homeostasis is an emergent property of both physical and biochemical signals emanating from neighboring cells and across tissue. A recent study reveals that Scribble, an apico-basal polarity determinant, cooperates with α-Catenin, an adhe
Externí odkaz:
https://doaj.org/article/0dff3367185d4cee998a9e676c969d61
Autor:
Samuel L Goldsmith, MaryJane Shimell, Petra Tauscher, Samantha M Daly, Osamu Shimmi, Michael B O’Connor, Stuart J Newfeld
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 4 (2022)
AbstractGenes on the long arm of the Drosophila melanogasterBloom syndrome helicaserecombination defective
Externí odkaz:
https://doaj.org/article/70077ddd1ab34674bbb50257a895457a
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 7, Pp 2399-2409 (2018)
Quantitative genetic variation in morphology is pervasive in all species and is the basis for the evolution of differences among species. The measurement of morphological form in adults is now beginning to be combined with comparable measurements of
Externí odkaz:
https://doaj.org/article/53dfb10e0f6b48d6baa4b53f5d1efd3a
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006424 (2016)
Epithelial cells are characterized by apical-basal polarity. Intrinsic factors underlying apical-basal polarity are crucial for tissue homeostasis and have often been identified to be tumor suppressors. Patterning and differentiation of epithelia are
Externí odkaz:
https://doaj.org/article/1f279a1d052f4ca188d817314509e623
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114475 (2014)
Bone morphogenetic proteins (BMPs), a subgroup of the transforming growth factor (TGF)-β family, transduce their signal through multiple components downstream of their receptors. Even though the components involved in the BMP signaling pathway have
Externí odkaz:
https://doaj.org/article/5a1b6ff1a7bd4387bd51c7b621721061
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003403 (2013)
A variety of extracellular factors regulate morphogenesis during development. However, coordination between extracellular signaling and dynamic morphogenesis is largely unexplored. We address the fundamental question by studying posterior crossvein (
Externí odkaz:
https://doaj.org/article/0f9ca6fcf294497aaf4ca19fb7c82e61