Interleukin 1β, Tumor Necrosis Factor Alpha, and Interleukin 8 in Bronchoalveolar Lavage Fluid of Patients with Diffuse Panbronchiolitis: A Potential Mechanism of Macrolide Therapy

Autor: Ryo Shirai, Shigeru Kohno, Jun-ichi Kadota, Osamu Sakito, Kohei Hara, Koh Abe

Publikováno v: Respiration. 63:42-48

We measured the levels of interleukin (IL) 1 beta, tumor necrosis factor alpha, and IL-8 in bronchoalveolar lavage fluid (BALF) and sera of patients with diffuse panbronchiolitis (DPB) before and after administration of erythromycin or roxithromycin.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb129b4d92579800317d54713689a339
https://doi.org/10.1159/000196514

Roxithromycin Treatment in Patients with Chronic Lower Respiratory Tract Disease

Autor: K. Iida, Kohei Hara, Koh Abe, Ryo Shirai, Shiro Kusano, Kaoru Kawakami, Toru Morikawa, Shigeru Kohno, Jun-ichi Kadota, Osamu Sakito

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 68:27-33

We demonstrated the efficacy of "long term" roxithromycin (RXM) treatment in 15 patients with chronic lower respiratory tract disease (11 with diffuse panbronchiolitis and 4 with sinobronchial syndrome). (1) Fourteen (93.3%) of the 15 patients showed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1cfd4b13a205a9cfa205532a1e39484
https://doi.org/10.11150/kansenshogakuzasshi1970.68.27

Effect of Erythromycin on Neutrophil Adhesion Molecules

Autor: Shiro KUSANO, Hiroshi MUKAE, Tohru MORIKAWA, Tsunehiko ASAI, Hideaki SAWA, Nobuo MORIKAWA, Hiroshige ODA, Osamu SAKITO, Chieko SHUKUWA, Reiko SENJU, Kazuyoshi KAWAKAMI, Kiyoyasu FUKUSHIMA, Jun-ichi KADOTA, Shigeru KOHNO, Kohei HARA

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 67:7-11

The mechanisms of erythromycin (EM) in chronic lower respiratory tract diseases including diffuse panbronchiolitis (DPB) has been reported. In this study we investigated the effect of EM on peripheral neutrophil adhesion molecules such as LFA-1 and M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdb7104202c8e416a5598d9d88c62be
https://doi.org/10.11150/kansenshogakuzasshi1970.67.7

Effect of Erythromycin on Intrapulmonary Influx of Neutrophils by Intratracheal Injection of Lipopolysaccharid

Autor: Senju R, Tsunehiko Asai, Kiyokazu Komori, Jun-ichi Kadota, S. Kawamoto, Kohei Hara, Hiroshi Mukae, Hiroshige Oda, Chieko Shukuwa, Shiro Kusano, M. Kaseda, Hideaki Sawa, Nobuo Morikawa, Kazuhito Hiratani, Osamu Sakito, Atsushi Yokoyama, Toru Morikawa, Kiyoyasu Fukushima, Masaki Hirota, Shigeru Kohno

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 66:194-200

Recently, "low dose and long term" erythromycin (EM) treatment has been reported as effective on chronic lower respiratory tract disease, including diffuse panbronchiolitis (DPB). However the effective mechanism of EM is still obscure. In this study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa37ef06d73ce1cf72c71f96b7d73c3b
https://doi.org/10.11150/kansenshogakuzasshi1970.66.194

Clinical Evaluation of Cefuzonam (CZON) for Bacterial Pneumonia and Lung Abscess Comparative Study with Cefotiam (CTM)

Autor: Hiroyuki KOBAYASHI, Hiroshi OSHITANI, Masahiko YOSHIDA, Akira SAITO, Ichiro NAKAYAMA, Kazuo TAKEBE, Mitsuo MASUDA, Seiichi MURAKAMI, Hiroaki TANAKA, Tsukiko TOMIYAMA, Kenichi KIMURA, Kazuya KANNARI, Shiro KOSAKA, Kiyoshi KONNO, Kotaro OIZUMI, Akira WATANABE, Yutaka TOKUE, Reiko ONO, Yoshihiro HONDA, Satoshi SHOJI, Naoto KITAMURA, Izumi HAYASHI, Masaaki ARAKAWA, Masanaga TAKATO, Koichi WADA, Norio SUZUKI, Kaoru SHIMADA, Yasuyuki SANO, Yasuo ARAI, Hiroichi TANIMOTO, Koichiro NAKATA, Yoshitaka NAKAMORI, Tatsuo NAKATANI, Hiroshi NARUI, Shigeki ODAGIRI, Kaneo SUZUKI, Kou MUROHASHI, Hiroyuki NUMATA, Kenichi TAKAHASHI, Izumi KOYAMA, Shunichi ISHII, Fumio MIKI, Rinzo SOEJIMA, Jiro HINO, Toshiharu MATSUSHIMA, Jun TANABE, Osamu KURIMURA, Hideo SASAKI, Hirofumi FUKUHARA, Tadao MORIMOTO, Kohei HARA, Shigeru KOHNO, Hironobu KOGA, Yasumasa DOUTSU, Toshiaki HAYASHI, Mitsuo KAKU, Shinichiro KANZAKI, Masao NAKATOMI, Kohta KOHNO, Takakazu KITANI, Hiroshi TOMITA, Osamu SAKITO, Keizo MATSUMOTO, Tsuyoshi NAGATAKE, Naoto RIKITOMI, Atsushi TAKAHASHI, Masakazu TAKASUGI, Hironori MASAKI, Masaru NASU, Yoichiro GOTO, Hideaki SHIGENO, Jun GOTO, Takayoshi TASHIRO, Atsushi SAITO, Yoshiteru SHIGENO, Yuei IRABU, Keizo YAMAGUCHI, Kazuyuki SUGAHARA, Chikako MOCHIDA, Mitsuyoshi NAKASHIMA

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 65:381-399

A double blind study was conducted to objectively evaluate the usefulness of Cefuzonam (CZON) in the treatment of bacterial pneumonia and lung abscess. Cefotiam (CTM) was used as a control drug. Each drug was administered by intravenous drip infusion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9d86b92eb92b643ff13dc0c3af229f
https://doi.org/10.11150/kansenshogakuzasshi1970.65.381