Zobrazeno 1 - 10
of 310
pro vyhledávání: '"Osamu NAGANO"'
Autor:
Fumimasa Kitamura, Takashi Semba, Noriko Yasuda-Yoshihara, Kosuke Yamada, Akiho Nishimura, Juntaro Yamasaki, Osamu Nagano, Tadahito Yasuda, Atsuko Yonemura, Yilin Tong, Huaitao Wang, Takahiko Akiyama, Kazuki Matsumura, Norio Uemura, Rumi Itoyama, Luke Bu, Lingfeng Fu, Xichen Hu, Feng Wei, Kosuke Mima, Katsunori Imai, Hiromitsu Hayashi, Yo-ichi Yamashita, Yuji Miyamoto, Hideo Baba, Takatsugu Ishimoto
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Glycolysis is highly enhanced in pancreatic ductal adenocarcinoma (PDAC) cells; thus, glucose restrictions are imposed on nontumor cells in the PDAC tumor microenvironment (TME). However, little is known about how such glucose competition alters meta
Externí odkaz:
https://doaj.org/article/f3cb47775802480a848b7f0f3290f90a
Autor:
Hirotaka Hasegawa, Masahiro Shin, Jun Kawagishi, Hidefumi Jokura, Toshinori Hasegawa, Takenori Kato, Mariko Kawashima, Yuki Shinya, Hiroyuki Kenai, Takuya Kawabe, Manabu Sato, Toru Serizawa, Osamu Nagano, Kyoko Aoyagi, Takeshi Kondoh, Masaaki Yamamoto, Shinji Onoue, Kiyoshi Nakazaki, Yoshiyasu Iwai, Kazuhiro Yamanaka, Seiko Hasegawa, Kosuke Kashiwabara, Nobuhito Saito
Publikováno v:
Journal of Stroke, Vol 24, Iss 2, Pp 278-287 (2022)
Background and Purpose To assess the long-term outcomes of intracranial dural arteriovenous fistula (DAVF) treated with stereotactic radiosurgery (SRS) alone or embolization and SRS (Emb-SRS) and to develop a grading system for predicting DAVF oblite
Externí odkaz:
https://doaj.org/article/85b48d4f30e84d708979936bc58cf2cb
Autor:
Kenji Tsuchihashi, Yuki Hirata, Juntaro Yamasaki, Kentaro Suina, Kenro Tanoue, Toshifumi Yae, Kenta Masuda, Eishi Baba, Koichi Akashi, Yuko Kitagawa, Hideyuki Saya, Osamu Nagano
Publikováno v:
Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101246- (2022)
Epithelial-mesenchymal plasticity (EMP) refers to the reversible cellular transition between epithelial and mesenchymal status. Spontaneous EMP is also reported in breast and prostate cancer, leading to the acquisition of stem-cell properties and che
Externí odkaz:
https://doaj.org/article/5824d7a6d235432790144d73e187a66d
Autor:
Tetsuya Yumoto, Takahisa Fujita, Sunao Asaba, Shunsuke Kanazawa, Atsunori Nishimatsu, Hideo Yamanouchi, Satoshi Nakagawa, Osamu Nagano
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-10 (2019)
Abstract Background Two recent large randomized controlled trials did not show the superiority of high-frequency oscillatory ventilation (HFOV) in adults with ARDS. These two trials had differing results, and possible causes could be the different os
Externí odkaz:
https://doaj.org/article/19ed28ec1603464d911ef704f89facd9
Autor:
Megumi Shiota, Masayuki Naya, Takehiro Yamamoto, Takako Hishiki, Takeharu Tani, Hiroyuki Takahashi, Akiko Kubo, Daisuke Koike, Mai Itoh, Mitsuyo Ohmura, Yasuaki Kabe, Yuki Sugiura, Nobuyoshi Hiraoka, Takayuki Morikawa, Keiyo Takubo, Kentaro Suina, Hideaki Nagashima, Oltea Sampetrean, Osamu Nagano, Hideyuki Saya, Shogo Yamazoe, Hiroyuki Watanabe, Makoto Suematsu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Surface-enhanced Raman spectroscopy (SERS) visualizes fingerprints of intermolecular vibrations of many metabolites. Here the authors report a SERS imaging technique that enables the visualization of metabolites distribution and automated extraction
Externí odkaz:
https://doaj.org/article/6370f21a7dce45e4b681376a2ad703d3
Autor:
Osamu Nagano, Tetsuya Yumoto, Atsunori Nishimatsu, Shunsuke Kanazawa, Takahisa Fujita, Sunao Asaba, Hideo Yamanouchi
Publikováno v:
Intensive Care Medicine Experimental, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Background Bias flow (BF) is essential to maintain mean airway pressure (MAP) and to washout carbon dioxide (CO2) from the oscillator circuit during high-frequency oscillatory ventilation (HFOV). If the BF rate is inadequate, substantial CO2
Externí odkaz:
https://doaj.org/article/e53faec66dfb4e0bb0f8fb974ab586a0
Autor:
Amanda Sosulski, Heiko Horn, Lihua Zhang, Caroline Coletti, Vinod Vathipadiekal, Cesar M Castro, Michael J Birrer, Osamu Nagano, Hideyuki Saya, Kasper Lage, Patricia K Donahoe, David Pépin
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156595 (2016)
CD44 is a transmembrane hyaluronic acid receptor gene that encodes over 100 different tissue-specific protein isoforms. The most ubiquitous, CD44 standard, has been used as a cancer stem cell marker in ovarian and other cancers. Expression of the epi
Externí odkaz:
https://doaj.org/article/a0d4541cbf034a48b1c7b8eeb1e46176
Autor:
Feng Wei, Tomoyuki Uchihara, Atsuko Yonemura, Noriko Yasuda‐Yoshihara, Tadahito Yasuda, Takashi Semba, Masahiro Fukuda, Takahiko Akiyama, Fumimasa Kitamura, Luke Bu, Xichen Hu, Lingfeng Fu, Jun Zhang, Ryusho Kariya, Juntaro Yamasaki, Kazuki Aihara, Kohei Yamashita, Osamu Nagano, Seiji Okada, Hideo Baba, Takatsugu Ishimoto
Publikováno v:
The FEBS Journal. 290:2604-2615
Fibroblast activation protein (FAP) generally shows low or undetectable expression in most normal tissues but is highly expressed in fibroblasts in almost all carcinomas. FAP is one of the potential molecules to detect activated fibroblasts and has m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59a7d238441723e93e07808fbdfe61b
https://doi.org/10.1111/febs.16712
https://doi.org/10.1111/febs.16712
Autor:
Takahiko Akiyama, Tadahito Yasuda, Tomoyuki Uchihara, Noriko Yasuda-Yoshihara, Benjy J.Y. Tan, Atsuko Yonemura, Takashi Semba, Juntaro Yamasaki, Yoshihiro Komohara, Koji Ohnishi, Feng Wei, Lingfeng Fu, Jun Zhang, Fumimasa Kitamura, Kohei Yamashita, Kojiro Eto, Shiro Iwagami, Hirotake Tsukamoto, Terumasa Umemoto, Mari Masuda, Osamu Nagano, Yorifumi Satou, Hideyuki Saya, Patrick Tan, Hideo Baba, Takatsugu Ishimoto
Publikováno v:
Cancer Research. 83:753-770
Excess stroma and cancer-associated fibroblasts (CAF) enhance cancer progression and facilitate immune evasion. Insights into the mechanisms by which the stroma manipulates the immune microenvironment could help improve cancer treatment. Here, we aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1009c6fac1d9909e2a316434917b067
https://doi.org/10.1158/0008-5472.can-22-1890
https://doi.org/10.1158/0008-5472.can-22-1890
Autor:
Osamu Nagano, Hideyuki Saya, James R. Goldenring, Yuko Kitagawa, Hirotoshi Hasegawa, Toshiro Sato, Masanobu Oshima, Hiroko Oshima, Momoko Yoshikawa, Shogo Okazaki, Kenji Tsuchihashi, Takeyuki Wada, Ryo Seishima
Supplemental Figure S1. Parietal cells loss induced by tamoxifen injection in WT mouse.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c032bdcf7a269c6634ac35211ae6d7
https://doi.org/10.1158/1940-6207.22525676
https://doi.org/10.1158/1940-6207.22525676
