Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Osamu Kumano"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Global fibrinolysis assays detect the fibrinolysis time of clot dissolution using tissue-type plasminogen activator (tPA). Two such assays, clot-fibrinolysis waveform analysis (CFWA) and global fibrinolysis capacity (GFC) assay, were recentl
Externí odkaz:
https://doaj.org/article/6592048c2ce042c0995734af58758168
Autor:
Tomoyo Saito, Mineji Hayakawa, Osamu Kumano, Yoshinori Honma, Mone Murashita, Jun Kato, Syouki Fukui, Masaki Takahashi, Yuki Takahashi, Takumi Tsuchida, Asumi Mizugaki, Shuhei Takauji, Mariko Hayamizu, Tomonao Yoshida, Kenichi Katabami, Takeshi Wada, Kunihiko Maekawa
Publikováno v:
Journal of Intensive Care, Vol 11, Iss 1, Pp 1-9 (2023)
Abstract Background Unfractionated heparin (UFH) is primarily monitored using activated partial thromboplastin time (APTT). However, the recent introduction of anti-activated factor X (anti-Xa) activity testing has provided a direct evaluation of Xa
Externí odkaz:
https://doaj.org/article/b45e57931d5e4a6ab8bbed1dc409f926
Publikováno v:
Exploration of Immunology, Vol 3, Iss 5, Pp 416-432 (2023)
Antiphospholipid syndrome (APS) is defined as an autoimmune and prothrombotic disorder in patients with the persistent presence of antiphospholipid antibodies (aPLs). In the classification criteria, aPL expresses lupus anticoagulant (LA) activity, wh
Externí odkaz:
https://doaj.org/article/467ad1c463c94856aeed6cf989a3dd68
Publikováno v:
Thrombosis Journal, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Supplementation with antithrombin (AT) concentrates is now common in the treatment of congenital and acquired AT deficiency. However, there is no established consensus on the target and timing of supplementation. We aimed to eluci
Externí odkaz:
https://doaj.org/article/63a01ff0453d4950bcd9cf2f5d556b1e
Autor:
Osamu Kumano, Gary W. Moore
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 3, Iss 4, Pp 695-703 (2019)
Abstract Background Lupus anticoagulant (LA) is classified in the antibody family that is recognized in antiphospholipid syndrome. Mixing tests are recommended for LA detection, and either a mixing test–specific cutoff (MTC) or index of circulating
Externí odkaz:
https://doaj.org/article/60e640b4695244c89ff3888e2aa6d74c
Publikováno v:
Biomedicines, Vol 9, Iss 3, p 264 (2021)
Anticoagulant drugs have been used to prevent and treat thrombosis. However, they are associated with risk of hemorrhage. Therefore, prior to their clinical use, it is important to assess the risk of bleeding and thrombosis. In case of older anticoag
Externí odkaz:
https://doaj.org/article/aba1ece8e90e427d8f454df4c03fb224
Publikováno v:
International Journal of Laboratory Hematology. 43:771-778
Background Lupus anticoagulants (LA) are detected by prolongation of clotting times for dilute Russell's viper venom time (dRVVT) and activated partial thromboplastin time (APTT) screening tests. Direct oral anticoagulants (DOACs) can interfere with
Autor:
Osamu, Kumano, Shinya, Suzuki, Masako, Yamazaki, Yoshimori, An, Masahiro, Yasaka, Masahiro, Ieko
Publikováno v:
International journal of laboratory hematologyREFERENCES.
A single assay to assess the effect of the direct FXa inhibitor is needed clinically because prothrombin (PT) assay is not yet sensitive enough for accurate evaluation. We developed modified diluted prothrombin time (mdPT) assay showing a high reacti
Autor:
Osamu Kumano, Mari Emmi, Yoichi Yuki, Masaru Homma, Masahiro Ieko, Yutaka Komiyama, Masato Matsuda, Hideaki Tanaka, Kaoru Tohyama, Kazuyoshi Miyata, Yohko Kawai, Chisato Shimazu, Toshihiko Okuhara, Sumiyoshi Naito, Rika Arai, Yasuji Sekine, Hisako Katagiri, Satoshi Yamazaki, Tetsuji Yamashita, Tatsuya Yoshida
Publikováno v:
International Journal of Hematology. 112:614-620
Accurate clotting time assay results are vital, as the test is employed to indicate the amount of oral anticoagulant to be prescribed, while it is also used for screening the hemorrhagic and thrombotic diseases. The procedure chosen for preparation o
Publikováno v:
Thrombosis research. 210