Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Osamu Iwasaki"'
Autor:
Osamu Iwasaki, Hideki Tanizawa, Kyoung-Dong Kim, Andrew Kossenkov, Timothy Nacarelli, Sanki Tashiro, Sonali Majumdar, Louise C. Showe, Rugang Zhang, Ken-ichi Noma
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-20 (2019)
Cell senescence involves stable arrest of cell proliferation and changes in gene expression and 3D genome reorganization. Here, the authors show that human condensin II complex participates in reorganization of the chromatin compartments, primarily t
Externí odkaz:
https://doaj.org/article/d6bfd9f78d8e46fe944d870a5010386b
Publikováno v:
BioTechniques, Vol 55, Iss 5, Pp 257-263 (2013)
We describe a series of new vectors for PCR-based epitope tagging and gene disruption in the fission yeast Schizosaccharomyces pombe, an exceptional model organism for the study of cellular processes. The vectors are designed for amplification of gen
Externí odkaz:
https://doaj.org/article/ef1e1bbdf353403e8da07d898a2a6019
Autor:
Kunihiko Ishizawa, Osamu Iwasaki, Hironori Oka, Takashi Sugawara, Masakuni Amari, Takeshi Kawarabayashi, Koichi Okamoto, Kimihiko Kaneko, Toshiyuki Takahashi, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji
Publikováno v:
Clinical and Experimental Neuroimmunology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0b6c8a224f75ee5eceaea745f84b10a
https://doi.org/10.1111/cen3.12753
https://doi.org/10.1111/cen3.12753
Autor:
Takeshi Sakuno, Sanki Tashiro, Hideki Tanizawa, Osamu Iwasaki, Da-Qiao Ding, Tokuko Haraguchi, Ken-ichi Noma, Yasushi Hiraoka
Publikováno v:
Nucleic Acids Research. 50:3799-3816
During meiotic prophase, cohesin-dependent axial structures are formed in the synaptonemal complex (SC). However, the functional correlation between these structures and cohesion remains elusive. Here, we examined the formation of cohesin-dependent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f48eaf72a53a8e2bb05b1698687dd9
https://doi.org/10.1093/nar/gkac183
https://doi.org/10.1093/nar/gkac183
Autor:
Hideki Tanizawa, Rugang Zhang, Osamu Iwasaki, Andrew V. Kossenkov, Sanki Tashiro, Ken-ichi Noma, Louise C. Showe, Kyoung-Dong Kim, Sonali Majumdar, Timothy Nacarelli
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-20 (2019)
Nature Communications
Nature Communications
Senescence is induced by various stimuli such as oncogene expression and telomere shortening, referred to as oncogene-induced senescence (OIS) and replicative senescence (RS), respectively, and accompanied by global transcriptional alterations and 3D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7682e4fd68adde0d48a43143f7f7b274
http://link.springer.com/article/10.1038/s41467-019-13604-5
http://link.springer.com/article/10.1038/s41467-019-13604-5
Autor:
Shuai Wu, Katherine M. Aird, Joseph A. Zundell, David W. Speicher, Takeshi Fukumoto, David C. Schultz, Ken-ichi Noma, Zachary T. Schug, Osamu Iwasaki, Lena Lau, Rugang Zhang, Timothy Nacarelli, Nail Fatkhutdinov, Hsin Yao Tang, Joseph A. Baur, Andrew V. Kossenkov, Gregory David
Publikováno v:
Nature Cell Biology. 21:397-407
Cellular senescence is a stable growth arrest that is implicated in tissue ageing and cancer. Senescent cells are characterized by an upregulation of proinflammatory cytokines, which is termed the senescence-associated secretory phenotype (SASP). NAD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f11553854a9f386f94acc43de93986c
https://doi.org/10.1038/s41556-019-0287-4
https://doi.org/10.1038/s41556-019-0287-4
Autor:
Eric F. Joyce, Rugang Zhang, Hsin-Yao Tang, Jennifer M. Luppino, David W. Speicher, Nail Fatkhutdinov, Shuai Wu, Ken-ichi Noma, Alessandro Gardini, Leah F Rosin, Andrew V. Kossenkov, Hideki Tanizawa, Osamu Iwasaki
Publikováno v:
Science Advances
ARID1A is important for genome folding, spatial partitioning of interphase chromosomes, and intermixing of small chromosomes.
ARID1A, a subunit of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complex, localizes to both promo
ARID1A, a subunit of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complex, localizes to both promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0cb70aea6ec53c8fcd117538a1bb455
http://europepmc.org/articles/PMC6531001
http://europepmc.org/articles/PMC6531001
Autor:
F. Brad Johnson, Osamu Iwasaki, Andrew V. Kossenkov, Linh Le, Gretchen M. Alicea, Hideki Tanizawa, Ting-Lin B. Yang, Nail Fatkhutdinov, Benjamin G. Bitler, Ken-ichi Noma, Katherine M. Aird, Rugang Zhang
Publikováno v:
The Journal of Cell Biology
In senescence, specific genes encoding secreted factors are excluded from senescence-associated heterochromatin foci, but the mechanisms underlying this senescence-associated secretory phenotype (SASP) are unclear. Aird et al. show that the chromatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e94e7dcb3ee5ce6ed0610318bffe1c0
https://doi.org/10.1083/jcb.201608026
https://doi.org/10.1083/jcb.201608026
Publikováno v:
Nucleic Acids Research
Chromosomes are not randomly disposed in the nucleus but instead occupy discrete sub-nuclear domains, referred to as chromosome territories. The molecular mechanisms that underlie the formation of chromosome territories and how they are regulated dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95278a2a14a8a0ef05df0f289e7162a
http://europepmc.org/articles/PMC4856965
http://europepmc.org/articles/PMC4856965
Autor:
Timothy, Nacarelli, Lena, Lau, Takeshi, Fukumoto, Joseph, Zundell, Nail, Fatkhutdinov, Shuai, Wu, Katherine M, Aird, Osamu, Iwasaki, Andrew V, Kossenkov, David, Schultz, Ken-Ichi, Noma, Joseph A, Baur, Zachary, Schug, Hsin-Yao, Tang, David W, Speicher, Gregory, David, Rugang, Zhang
Publikováno v:
Nature cell biology
Cellular senescence is a stable growth arrest that is implicated in tissue ageing and cancer. Senescent cells are characterized by an upregulation of proinflammatory cytokines, which is termed the senescence-associated secretory phenotype (SASP). NAD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25575a5c9505fcde740e5dcbdae61efa
https://pubmed.ncbi.nlm.nih.gov/30778219
https://pubmed.ncbi.nlm.nih.gov/30778219