Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Osamu Irino"'
Publikováno v:
Digestive diseases and sciences. 35(1)
The present study was designed to investigate the changes in gastric mucosal PGI2 level accompanying the healing of acetic acid-induced gastric ulcers in rats. The ulcers, which were observed with an endoscope, were found to undergo periods of decrea
Publikováno v:
Folia Pharmacologica Japonica. 91:105-109
The mode for the manifestation of the inhibitory effect of ifenprodil tartrate on platelet aggregation in vivo and ex vivo was studied in mice and men, respectively. The ifenprodil level in plasma reached the maximum in 20 min after oral administrati
Autor:
A Taguchi, N Nishimura, Osamu Irino, Tetsuji Kametani, Okada Taiji, Seiji Haga, Kazuo Kigasawa, Kikuo Wakisaka, T Yamamoto, Kazunaga Fukawa, Hideo Sugi, M Nakayama, Y Nagamatsu, Mineharu Hiiragi
Publikováno v:
Journal of Medicinal Chemistry. 23:1324-1329
A number of N-acyl and N-(alkoxycarbonyl)-5-fluorouracil derivatives possessing, for example, benzoyl, o-toluyl, acetyl, propionyl, heptanoyl, ethoxycarbonyl, phenoxycarbonyl, and benzyloxycarbonyl groups as N1 and/or N3 substituents were synthesized
Publikováno v:
Folia Pharmacologica Japonica. 86:17-23
Effects of choline salicylate, sodium salicylate, choline chloride and acetylsalicylic acid on platelet aggregation in vivo, ex vivo and in vitro in mice were studied. These drugs all inhibited adenosine diphosphate (ADP)-induced respiratory depressi
Publikováno v:
Japanese Journal of Pharmacology. 33:175-179
Publikováno v:
Folia Pharmacologica Japonica. 85:407-414
Adjuvant arthritic rats develop marked changes in the distal limb joints. These changes were observed by soft X-ray photography at appropriate intervals. It was confirmed that the "cotton wool appearance" surrounding the bones, which was readily disc
Autor:
Katsuharu Iwadate, Osamu Irino, Yoshihiko Ito, Takashi Sawabe, Kazunaga Fukawa, Shigeo Ohbayashi
Publikováno v:
YAKUGAKU ZASSHI. 102:89-98
Publikováno v:
Folia Pharmacologica Japonica. 83:69-77
Publikováno v:
Chemical and Pharmaceutical Bulletin. 20:734-740
The metabolites of IA (2-indanamine hydrochloride) have been investigated in rats and rabbits. When IA (100mg/kg) was administered to rats, following metabolites were found together with unchanged IA:cis-, trans-1-hydroxy-2-indanamine, cis-, trans-1,
Publikováno v:
YAKUGAKU ZASSHI. 88:1516-1522