Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Osamu Hiraoka"'
Autor:
Yoshinori Takahashi, Keisuke Kakinouchi, Tsuyoshi Inoue, Hiroaki Adachi, Shigeru Sugiyama, Satoshi Murakami, Osamu Hiraoka, Kazufumi Takano, Michio Murata, Hiroshi Yoshikawa, Hiroyoshi Matsumura, Mihoko Maruyama, Masashi Yoshimura, Yusuke Mori, Noriko Shimizu
Publikováno v:
Crystengcomm. 17(No. 42):8064-8071
Neutron macromolecule crystallography can determine the positions of hydrogen atoms in proteins, thereby clarifying the protein structure and function as well as enzyme mechanisms. It requires very large crystals to make up for the low flux of availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b11dd4407d3795f0e08788e5b4495e
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100713046
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100713046
Autor:
Yasuo Ariumi, Nobuyuki Kato, Yusuke Wataya, Osamu Hiraoka, Masanori Ikeda, Kyoko Mori, Akiko Hiramoto
Publikováno v:
Hepatology. 58:1236-1244
Ribavirin (RBV) is often used in conjunction with interferon-based therapy for patients with chronic hepatitis C. There is a drastic difference in the anti–hepatitis C virus (HCV) activity of RBV between the HuH-7-derived assay system, OR6, possess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebbf325336fae23494d7e959cc29a7fb
https://doi.org/10.1002/hep.26421
https://doi.org/10.1002/hep.26421
Autor:
Osamu Kaneko, Masatomo Nojima, Takaya Sakura, Masayuki Morita, Yusuke Wataya, Hitomi Sanai, Akira Sato, Hye Sook Kim, Osamu Hiraoka, Akiko Hiramoto, Araki Masuyama
Publikováno v:
Journal of Proteome Research. 11:5704-5711
The endoperoxide artemisinin is a current first-line antimalarial and a critical component of the artemisinin-based combination therapies (ACT) recommended by WHO for treatment of Plasmodium falciparum, the deadliest of malaria parasites. However, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12489e992802ebb9a675ad158a29f36e
https://doi.org/10.1021/pr3005315
https://doi.org/10.1021/pr3005315
Antimalarial activity of endoperoxide compound 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol
Autor:
Yuka Komich, Yukari Nakase, Akira Sato, Hye Sook Kim, Satoru Kawai, Kazutaka Higaki, Akiko Hiramoto, Araki Masuyama, Yusuke Wataya, Osamu Hiraoka, Kazuyuki Hiramoto, Hikoya Hayatsu, Masahiro Matsumoto, Masayuki Morita, Natsuki Tanigawa, Masatomo Nojima
Publikováno v:
Parasitology International. 60:270-273
Plasmodium falciparum , the major causative parasite for the disease, has acquired resistance to most of the antimalarial drugs used today, presenting an immediate need for new antimalarial drugs. Here, we report the in vitro and in vivo antimalarial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf69a94da3f53872a7ac831565eb1b8
https://doi.org/10.1016/j.parint.2011.04.001
https://doi.org/10.1016/j.parint.2011.04.001
Autor:
Yusuke Wataya, Masatomo Nojima, Kazuyuki Hiramoto, Hye Sook Kim, Jin Ming Wu, Akiko Hiramoto, Araki Masuyama, Hiroyuki Kataoka, Satoru Kawai, Osamu Hiraoka, Hitomi Sanai, Nagwa S. M. Aly
Publikováno v:
Parasitology Research. 100:1119-1124
N-89, a new antimalarial endoperoxide, was selected as a promising antimalarial compound showing high activity and selectivity. To study the mechanism of N-89 action, N-89 resistant strain (NRC10) was obtained by intermittent drug pressure. NRC10 had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c47b59eab50b11d10d3116b3b592021
https://doi.org/10.1007/s00436-007-0460-8
https://doi.org/10.1007/s00436-007-0460-8
Publikováno v:
Protein & Peptide Letters. 2:425-430
The amino terminal domain of the cytokine receptor homologous region (BN domain1 roughly 100 amino acid residues) in the receptor for human granulocyte colony-stimulating factor (G-CSF) was produced by an Eschetichia coli maltose binding protein (MBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7608618e1d2c9d260e45412b40671e21
https://doi.org/10.2174/092986650203220601165211
https://doi.org/10.2174/092986650203220601165211
Publikováno v:
Journal of Biological Chemistry. 270:27845-27851
The carboxyl-terminal domain (BC domain, roughly 100 amino acid residues) of the cytokine receptor homologous region in the receptor for murine granulocyte colony-stimulating factor was secreted as a maltose binding protein fusion into the Escherichi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94bf5361562dac39478561368e9c5c2
https://doi.org/10.1074/jbc.270.46.27845
https://doi.org/10.1074/jbc.270.46.27845
Autor:
Kento Hashido, Chikara Miyamoto, Kenji Wada, Hiromichi Terashima, Osamu Hiraoka, Yasuhiro Furuichi, Yukako Fujii, Miki Adachi
Publikováno v:
Protein Expression and Purification. 6:228-236
We have employed both protein chemical and molecular biological approaches to determine the ligand binding domain of the endothelin-B subtype (ETB) receptor. The human ETB receptor purified from human placenta by using affinity chromatography was cro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d9d099acf3ad49731ea107ee5be9fb
https://doi.org/10.1006/prep.1995.1029
https://doi.org/10.1006/prep.1995.1029
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 59:2351-2354
The cytokine receptor homologous (CRH) region of the murine granulocyte colony-stimulating factor (G-CSF) receptor was secreted using a Escherichia coli maltose binding protein (MBP) fusion system. The CRH region was prepared from the periplasmic fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a13df0294361d88fc6814c29055e49
https://doi.org/10.1271/bbb.59.2351
https://doi.org/10.1271/bbb.59.2351
Autor:
Kyoko, Mori, Osamu, Hiraoka, Masanori, Ikeda, Yasuo, Ariumi, Akiko, Hiramoto, Yusuke, Wataya, Nobuyuki, Kato
Publikováno v:
Hepatology (Baltimore, Md.). 58(4)
Ribavirin (RBV) is often used in conjunction with interferon-based therapy for patients with chronic hepatitis C. There is a drastic difference in the anti-hepatitis C virus (HCV) activity of RBV between the HuH-7-derived assay system, OR6, possessin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d8980ab62c738e8c9c0f2f9cb4d4770
https://pubmed.ncbi.nlm.nih.gov/23703706
https://pubmed.ncbi.nlm.nih.gov/23703706