Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Osamu Hiraike-Wada"'
Autor:
Yu Takahashi, Kenbun Sone, Katsuhiko Noda, Kaname Yoshida, Yusuke Toyohara, Kosuke Kato, Futaba Inoue, Asako Kukita, Ayumi Taguchi, Haruka Nishida, Yuichiro Miyamoto, Michihiro Tanikawa, Tetsushi Tsuruga, Takayuki Iriyama, Kazunori Nagasaka, Yoko Matsumoto, Yasushi Hirota, Osamu Hiraike-Wada, Katsutoshi Oda, Masanori Maruyama, Yutaka Osuga, Tomoyuki Fujii
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248526 (2021)
Endometrial cancer is a ubiquitous gynecological disease with increasing global incidence. Therefore, despite the lack of an established screening technique to date, early diagnosis of endometrial cancer assumes critical importance. This paper presen
Externí odkaz:
https://doaj.org/article/b722390c5c694f02bc7fce6fe0772138
Autor:
Osamu Hiraike-Wada, Katsuhiko Noda, Haruka Nishida, Kaname Yoshida, Asako Kukita, Yu Takahashi, Kosuke Kato, Kazunori Nagasaka, Yoko Matsumoto, Ayumi Taguchi, Masanori Maruyama, Kenbun Sone, Yutaka Osuga, Takayuki Iriyama, Michihiro Tanikawa, Yusuke Toyohara, Yasushi Hirota, Futaba Inoue, Katsutoshi Oda, Tomoyuki Fujii, Yuichiro Miyamoto, Tetsushi Tsuruga
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248526 (2021)
PLoS ONE
PLoS ONE
Endometrial cancer is a ubiquitous gynecological disease with increasing global incidence. Therefore, despite the lack of an established screening technique to date, early diagnosis of endometrial cancer assumes critical importance. This paper presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce1db081144764e1cdb57ccede2e1bb
https://doaj.org/article/b722390c5c694f02bc7fce6fe0772138
https://doaj.org/article/b722390c5c694f02bc7fce6fe0772138
Autor:
Kenbun Sone, Hiroyuki Kuramoto, Katsutoshi Oda, S Hosokawa, Tetsu Yano, Shunsuke Nakagawa, Kei Kawana, Yuji Taketani, Haruko Hiraike, Genta Nagae, Kumi Shoji, Tomomi Nei, Yuriko Uehara, Osamu Hiraike-Wada, Yuichiro Miyamoto, Hiroyuki Aburatani
Publikováno v:
British Journal of Cancer
Background: The phosphatidylinositol 3′-kinase (PI3K)–AKT pathway is activated in many human cancers and plays a key role in cell proliferation and survival. A mutation (E17K) in the pleckstrin homology domain of the AKT1 results in constitutive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db74df6e52e2d6abc2f304cd9ea39bb2
http://europepmc.org/articles/PMC2713716
http://europepmc.org/articles/PMC2713716
Autor:
Koji Kugu, Yuichiro Miyamoto, Yuji Taketani, Keiichi Nakagawa, Yoko Matsumoto, Shin Takizawa, Haruko Hiraike, Shunsuke Nakagawa, Tetsu Yano, Katsutoshi Oda, Kazunori Nagasaka, Osamu Hiraike-Wada, Toshiharu Yasugi, Kenbun Sone, Tetsushi Tsuruga
Publikováno v:
Genes to Cells. 13:771-785
hScrib, human homologue of Drosophila neoplastic tumor suppressor, was identified as a target of human papillomavirus E6 oncoprotein for the ubiquitin-mediated degradation. Here, we report that hScrib is a novel death substrate targeted by caspase. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f13a69a86d24bd3ae5bb76a19d6a597
https://doi.org/10.1111/j.1365-2443.2008.01204.x
https://doi.org/10.1111/j.1365-2443.2008.01204.x
Autor:
Takeo Minaguchi, Shunsuke Nakagawa, Kazunori Nagasaka, Keiichi Nakagawa, Tetsushi Tsuruga, Katsutoshi Oda, Yoko Matsumoto, Osamu Hiraike-Wada, Shin Takizawa, Yuji Taketani, Hajime Ooishi, Tetsu Yano, Toshiharu Yasugi
Publikováno v:
Cancer Science. 97:1217-1225
Drosophila tumor suppressor Scribble has been identified as an apical-basolateral polarity determinant in epithelia. A human homolog of Drosophila Scribble, human Scribble (hScrib), has been identified as a protein targeted by human papillomavirus E6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9563bb7732e1b8492115f35e23ec71
https://doi.org/10.1111/j.1349-7006.2006.00315.x
https://doi.org/10.1111/j.1349-7006.2006.00315.x
Autor:
Tetsu Yano, Katsutoshi Oda, Hiroki R. Ueda, Yuriko Uehara, Tomoyuki Fujii, Kei Kawana, Hiroyuki Aburatani, Kenji Tatsuno, Shogo Yamamoto, Yutaka Osuga, Kayo Asada, Osamu Hiraike-Wada, Kenbun Sone, Reiko Kurikawa, Yuji Ikeda, Kengo Gotoh
Publikováno v:
Cancer Research. 75:4917-4917
Objectives: Circulating cell-free DNA (cfDNA) is expected to be useful for diagnosis of genetic alterations in cancer. However, it has been still difficult to comprehensively analyze somatic mutations using cfDNA, because of the low quantity in blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6dbe8a5eeb9ff1965ce016f3aaec04a
https://doi.org/10.1158/1538-7445.am2015-4917
https://doi.org/10.1158/1538-7445.am2015-4917
Autor:
Shunsuke Nakagawa, Osamu Hiraike-Wada, Katsutoshi Oda, Tetsu Yano, Tomoko Kashiyama, Yuji Ikeda, Tomoyuki Fujii, Kei Kawana, Aki Miyasaka, Yoshihiro Kikuchi, Takahiro Koso, Osamu Tetsu, Shiro Kozuma, Daichi Maeda
Publikováno v:
Cancer Research. 73:1748-1748
Introduction. Cyclin D1 is an important regulator of cell cycle progression. Phosphorylation of cyclin D1 at Thr-286 by GSK3beta triggers nuclear export and its cytoplasmic proteolysis via the 26S proteasome. Cyclin D1 overexpression is a common even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82b15759d6bae3071555320730c6afe4
https://doi.org/10.1158/1538-7445.am2013-1748
https://doi.org/10.1158/1538-7445.am2013-1748
Autor:
Yasuhide Hirora, Shunsuke Nakagawa, Tomoko Kashiyama, Tomoyuki Fujii, Kei Kawana, Yoshinobu Shiose, Aki Miyasaka, Katsutoshi Oda, Tomohiko Fukuda, Keiko Shoji, Tetsu Yano, Kazunori Nagasaka, Kanako Inaba, Michihiro Tanikawa, Takahiro Koso, Shiro Kozuma, Osamu Hiraike-Wada, Yuji Ikeda, Hiroyuki Aburatani
Publikováno v:
Cancer Research. 73:525-525
Background:Epithelial ovarian cancer is a leading cause of death from gynecological malignancies.Ovarian clear cell adenocarcinoma (OCCA) is the second most common cause of death from ovarian cancer with a higher incidence in Asia, especially Japan (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7ba3d316c28747f5cb5e566464ffbff
https://doi.org/10.1158/1538-7445.am2013-525
https://doi.org/10.1158/1538-7445.am2013-525
Autor:
Hiroyuki Kuramoto, Kumi Shoji, Genta Nagae, Katsutoshi Oda, Yuriko Uehara, Tetsu Yano, Tomomi Nei, Kei Kawana, Yuji Taketani, Haruko Hiraike, Yuichiro Miyamoto, S Hosokawa, Suguru Nakagawa, Hiroyuki Aburatani, Kenbun Sone, Osamu Hiraike-Wada
Publikováno v:
British Journal of Cancer
Reply: Somatic mutations are present in all members of the AKT family in endometrial carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb4dfed413a351cfd17c91b6dcab8d5
https://doi.org/10.1038/sj.bjc.6605302
https://doi.org/10.1038/sj.bjc.6605302
Autor:
Hiroyuki Kuramoto, Michihiro Tanikawa, Shiro Kozuma, Tetsu Yano, Yuji Ikeda, Katsutoshi Oda, M. Nishida, Kumi Shoji, Yuichiro Miyamoto, Tomoko Kashiyama, Osamu Hiraike-Wada, Yuji Taketani, Shunsuke Nakagawa
Publikováno v:
Journal of Clinical Oncology. 29:5110-5110
5110 Background: PI3K (phosphatidylinositol-3-kinase) /mTOR (mammalian target of rapamycin) pathway is frequently activated in endometrial cancer through various PI3K/AKT activating genetic alterat...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a8855bf256d07fcaf9045a5a1d6f4da
https://doi.org/10.1200/jco.2011.29.15_suppl.5110
https://doi.org/10.1200/jco.2011.29.15_suppl.5110