Výsledky vyhledávání - "Osamu HOSONO"

Akademický článek

Serum soluble CD26/DPP4 titer variation is a potential prognostic biomarker in cancer therapy with a humanized anti-CD26 antibody

Publikováno v: Biomarker Research, Vol 9, Iss 1, Pp 1-13 (2021)

Abstract Background The phase I trial of the humanized anti-CD26 monoclonal antibody YS110 for CD26-expressing tumors was conducted recently. The present study identifies a potential prognostic biomarker for CD26-targeted therapy based on the phase I

Externí odkaz: https://doaj.org/article/869532e7d9924a45b065a8c40a83cd05

Zobrazit plný text záznamu

Akademický článek

Oral MucoRice-CTB vaccine for safety and microbiota-dependent immunogenicity in humans: a phase 1 randomised trial

Autor: Yoshikazu Yuki, PhD, Masanori Nojima, MD, Osamu Hosono, MD, Hirotoshi Tanaka, ProfMD, Yasumasa Kimura, PhD, Takeshi Satoh, PhD, Seiya Imoto, ProfPhD, Satoshi Uematsu, ProfMD, Shiho Kurokawa, PhD, Koji Kashima, PhD, Mio Mejima, PhD, Rika Nakahashi-Ouchida, PhD, Yohei Uchida, MS, Takanori Marui, MS, Noritada Yoshikawa, MD, Fumitaka Nagamura, ProfMD, Kohtaro Fujihashi, ProfDDS, Hiroshi Kiyono, ProfDDS

Publikováno v: The Lancet Microbe, Vol 2, Iss 9, Pp e429-e440 (2021)

Summary: Background: There are an estimated 1·3–4·0 million cases of cholera and 20 000–140 000 cholera-related deaths worldwide each year. The rice-based cholera toxin B subunit (CTB) vaccine, MucoRice-CTB, is an oral candidate vaccine that do

Externí odkaz: https://doaj.org/article/b7638b4df71d421f8e095b3d4a553c5c

Zobrazit plný text záznamu

Akademický článek

Normal pressure hydrocephalus, a possible complication in IgG4-related disease

Autor: Hiroshi Kobayashi, Masaaki Uehara, Aya Oda, Erika Matsubara, Hiroyuki Baba, Ryo Matsumiya, Noritada Yoshikawa, Osamu Hosono, Hirotoshi Tanaka

Publikováno v: Interdisciplinary Neurosurgery, Vol 5, Iss C, Pp 1-2 (2016)

We report a 75-year-old man with glucocorticoid-responsive normal pressure hydrocephalus (NPH) complicated with tubulointerstitial renal disease, protein-losing gastroenteropathy (PLG) and elevated serum IgG4, which might be a possible subset of IgG4

Externí odkaz: https://doaj.org/article/b17ec95037c749fdbd1482d4529f8790

Zobrazit plný text záznamu

Akademický článek

Clinical significance of soluble CD26 in malignant pleural mesothelioma.

Autor: Nobukazu Fujimoto, Kei Ohnuma, Keisuke Aoe, Osamu Hosono, Taketo Yamada, Takumi Kishimoto, Chikao Morimoto

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e115647 (2014)

There is no established single diagnostic marker for malignant pleural mesothelioma (MPM). CD26 is a 110 kDa, multifunctional, membrane-bound glycoprotein that has dipeptidyl peptidase IV (DPPIV) enzyme activity. The aim of this study was to evaluate

Externí odkaz: https://doaj.org/article/8dc738fc011143d09f9620857cc71d1c

Zobrazit plný text záznamu

Akademický článek

Cardiomyocyte-specific overexpression of HEXIM1 prevents right ventricular hypertrophy in hypoxia-induced pulmonary hypertension in mice.

Autor: Noritada Yoshikawa, Noriaki Shimizu, Takako Maruyama, Motoaki Sano, Tomohiro Matsuhashi, Keiichi Fukuda, Masaharu Kataoka, Toru Satoh, Hidenori Ojima, Takashi Sawai, Chikao Morimoto, Akiko Kuribara, Osamu Hosono, Hirotoshi Tanaka

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e52522 (2012)

Right ventricular hypertrophy (RVH) and right ventricular (RV) contractile dysfunction are major determinants of prognosis in pulmonary arterial hypertension (PAH) and PAH remains a severe disease. Recently, direct interruption of left ventricular hy

Externí odkaz: https://doaj.org/article/e1f375ef7c804117a19e6ad1d396bfbf

Zobrazit plný text záznamu

Data from CD26 Overexpression Is Associated with Prolonged Survival and Enhanced Chemosensitivity in Malignant Pleural Mesothelioma

Autor: Chikao Morimoto, Takumi Kishimoto, Kouki Inai, Yukio Takeshima, Nam H. Dang, Taketo Yamada, Masanori Fujii, Akio Hiraki, Osamu Hosono, Kei Ohnuma, Nobukazu Fujimoto, Vishwa Jeet Amatya, Keisuke Aoe

Purpose: Malignant pleural mesothelioma (MPM) is an aggressive and therapy-resistant neoplasm arising from the pleural mesothelial cells, without established indicators to predict responsiveness to chemotherapy.Experimental Design: Our study involvin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305a868318f2fa5f7f47bc374f47c28e
https://doi.org/10.1158/1078-0432.c.6520115

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání