Výsledky vyhledávání

Nontoxic Enantiomeric Reference Materials for Saxitoxins

Autor: Ryuichi Watanabe, Yuka Takayanagi, Osamu Chiba, Shota Itoda, Hayate Ishizuka, Minami Odagi, Mayu Ozawa, Hajime Uchida, Ryoji Matsushima, Keiichi Konoki, Mari Yotsu-Yamashita, Kazuo Nagasawa, Toshiyuki Suzuki

Publikováno v: Analytical chemistry. 94(32)

Saxitoxin (STX) is a potent neurotoxin that is biosynthesized by toxic dinoflagellates and accumulated in shellfish via the food chain. STX and its various analogues are now monitored in shellfish by the hygiene authorities in many countries with ins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5741beed5232c97b57ab1f198e54a8da
https://pubmed.ncbi.nlm.nih.gov/35938415

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Synthesis of C12-Keto Saxitoxin Derivatives with Unusual Inhibitory Activity Against Voltage-Gated Sodium Channels

Autor: Keiichi Konoki, Kanna Adachi, Osamu Chiba, Masafumi Hidaka, Noriko Shimada, Mari Yotsu-Yamashita, Tatsuya Orihara, Kazuo Nagasawa, Takatsugu Hirokawa, Tomoshi Yamada, Hayate Ishizuka, Minami Odagi, Shunsuke Tsunogae, Mana Oki

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 26(9)

A novel series of C12-keto-type saxitoxin (STX) derivatives bearing an unusual nonhydrated form of the ketone at C12 has been synthesized, and their NaV -inhibitory activity has been evaluated in a cell-based assay as well as whole-cell patch-clamp r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4a747fa1cf8be8868f4768b3bda0ef
https://pubmed.ncbi.nlm.nih.gov/31769085

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Response control performance of a hybrid mass damper applied to a tall building

Autor: Osamu Chiba, Nobuyuki Izumi, Hiromichi Ebisawa, Takafumi Fujita, Masanobu Tohdo, Morimasa Watakabe

Publikováno v: Earthquake Engineering & Structural Dynamics. 30:1655-1676

A hybrid mass damper system with convertible active and passive modes using a hydraulic actuator (hereinafter referred to as APMD) has been installed to an actual slender tall building with an aspect ratio of eight constructed in Chiba prefecture. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a7f3df1c449d85bb851851a8e86d5ae
https://doi.org/10.1002/eqe.86

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Helicopter Observations of the Sea Breeze over a Coastal Area

Autor: Koji Sassa, Fumiaki Kobayashi, Gen’ichi Naito, Osamu Chiba

Publikováno v: Journal of Applied Meteorology. 38:481-492

Thermodynamical observations by a helicopter have been conducted to study the internal structure of the sea breeze blowing inland from Tosa Bay during three periods (September 1993, November 1994 and 1995). Inland-intrusion distances of the midday se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::059703fbc01ff63b491ed7dc26675251
https://doi.org/10.1175/1520-0450(1999)038<0481:hootsb>2.0.co

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VARIABILITY OF THE SEA-BREEZE FRONT FROM SODAR MEASUREMENTS}

Autor: Osamu Chiba

Publikováno v: Boundary-Layer Meteorology. 82:165-174

Using sodar measurements of the wind in the vicinity of sea-breeze fronts, we have investigated the lateral movement of the incoming front. A characteristic of the sea-breeze front is related to periodic oscillations in wind direction, which are like

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e24a59ffce5cfa8f529b984195e55c13
https://doi.org/10.1023/a:1000216406527

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Reconstructive method after basal cell carcinoma excision of the face

Autor: Tetsunori Yoshida, Chu Kimura, Osamu Chiba, Ritsuo Sakamura, Kenji Asami

Publikováno v: Skin Cancer. 11:57-62

We obtained cosmetically satisfactory results by using diverse flaps for reconstruction after excision of basal cell carcinoma of the face.Wide local excision is necessary for surgical treatment of malignant skin tumors, asin the case of facial areas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::886a083c182c4d957679cc8963b984a5
https://doi.org/10.5227/skincancer.11.57

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