Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Osamu, Inanami"'
Autor:
Yuto Goto, Kanta Ando, Hideo Takakura, Kohei Nakajima, Masato Kobayashi, Osamu Inanami, Tetsuya Taketsugu, Mikako Ogawa
Publikováno v:
Journal of Photochemistry and Photobiology, Vol 20, Iss , Pp 100230- (2024)
Near-infrared photoimmunotherapy (NIR-PIT) is a recently described method for cancer treatment that utilizes an antibody-conjugated phthalocyanine photosensitizer and NIR light. In NIR-PIT, light of 690 nm wavelength is used to activate a photosensit
Externí odkaz:
https://doaj.org/article/ae9cc01e20ad480b866e264cba63e411
Autor:
Koki Ogawara, Osamu Inanami, Hideo Takakura, Kenichiro Saita, Kohei Nakajima, Sonu Kumar, Naoya Ieda, Masato Kobayashi, Tetsuya Taketsugu, Mikako Ogawa
Publikováno v:
Advanced Science, Vol 11, Iss 12, Pp n/a-n/a (2024)
Abstract Caged compounds are frequently used in life science research. However, the light used to activate them is commonly absorbed and scattered by biological materials, limiting their use to basic research in cells or small animals. In contrast, h
Externí odkaz:
https://doaj.org/article/29b0e528c66544eb8b33bdfc60b8efa6
Autor:
Tatsuya Deguchi, Kenji Hosoya, Shango Kim, Yusuke Murase, Kumiko Yamamoto, Tomoki Bo, Hironobu Yasui, Osamu Inanami, Mahiro Okumura
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 143-151 (2021)
Metformin has many anti-cancer effects, alone or in combination with radiation. However, the mechanism underlying its radio-sensitized effect is still unclear, especially for cancer stem-like cells (CSCs). Here, the radio-sensitized effect of metform
Externí odkaz:
https://doaj.org/article/12a605f119294206adcc769a6eac61c1
Publikováno v:
Translational Oncology, Vol 21, Iss , Pp 101431- (2022)
Glutamine metabolism, known as glutaminolysis, is abnormally activated in many cancer cells with KRAS or BRAF mutations or active c-MYC. Glutaminolysis plays an important role in the proliferation of cancer cells with oncogenic mutations. In this stu
Externí odkaz:
https://doaj.org/article/23dd6960e54e491ba3abb30c9d5a97c7
Publikováno v:
Experimental Animals; 2024, Vol. 73 Issue 3, p302-309, 8p
Autor:
Tomoki Bo, Sho Kobayashi, Osamu Inanami, Junichi Fujii, Osamu Nakajima, Tsunekata Ito, Hironobu Yasui
Publikováno v:
Translational Oncology, Vol 14, Iss 11, Pp 101212- (2021)
L-type amino acid transporter 1 (LAT1) is important for transporting neutral amino acids into cells. LAT1 expression is correlated with cancer malignancy, suggesting that LAT1 is a promising target for cancer therapy. JPH203, a potential novel drug t
Externí odkaz:
https://doaj.org/article/2b874841681c4b269ee36071d16dabfa
Autor:
Yuki Matsuo, Kunihiko Nakai, Nozomi Tatsuta, Osamu Inanami, Kumiko Yamamoto, Hazuki Mizukawa, Hiromitsu Nagasaka, Futoshi Mizutani, Youichi Chisaki, Toshiki Aiba, Takashi Ohba, Izumi Watanabe, Hiromi Nabeshi, Taiki Higuchi, Yuki Koga, Hideaki Matsumoto, Kou Nishimuta, Hideki Miyamoto, Tomokazu Haraguchi, Noriko Ryuda, Daisuke Ueno
Publikováno v:
Physics Open, Vol 6, Iss , Pp 100060- (2021)
The environmental monitoring survey using this organisms was called “Caddisfly Watch” and this activity has involved both scientists and local people for collecting them.A simple method is needed for the continuous monitoring of radiocesium (137C
Externí odkaz:
https://doaj.org/article/b9ebc65acff2447daa6c054cdb0e05db
Autor:
Ririko Nakaoka, Kazuhiro Kato, Kumiko Yamamoto, Hironobu Yasui, Shingo Matsumoto, Igor A. Kirilyuk, Valery V. Khramtsov, Osamu Inanami, Hiroshi Hirata
Publikováno v:
Analytical Chemistry. 95:3940-3950
Extracellular acidification indicates a metabolic shift in cancer cells and is, along with tissue hypoxia, a hallmark of tumor malignancy. Thus, non-invasive mapping of extracellular pH (pHe) is essential for researchers to understand the tumor micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0a5c5e440bd74b4d1eecf910083bbf
https://doi.org/10.1021/acs.analchem.2c03194
https://doi.org/10.1021/acs.analchem.2c03194
Publikováno v:
Translational Oncology, Vol 10, Iss 4, Pp 491-500 (2017)
Checkpoint kinase 1 (Chk1) is an evolutionarily conserved serine/threonine kinase that plays an important role in G2/M checkpoint signaling. Here, we evaluate the radiosensitizing effects of a novel selective Chk1 inhibitor MK-8776, comparing its eff
Externí odkaz:
https://doaj.org/article/d7ba33c04db94279b3d6d698326303f0
Autor:
Mayuko Hashimoto, Natsuko Saito, Haru Ohta, Kumiko Yamamoto, Asuka Tashiro, Kosuke Nakazawa, Osamu Inanami, Hiroshi Kitamura
Publikováno v:
Physiological Reports, Vol 7, Iss 14, Pp n/a-n/a (2019)
Abstract Ubiquitin‐specific protease 2 (USP2) is considered to participate in the differentiation of myoblasts to myotubes, however, its functions in myoblasts under growth conditions remain elusive. In this study, we analyzed the physiological rol
Externí odkaz:
https://doaj.org/article/c922ea8db5c845c485c67d12f572c1e9