Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Osamu, Honmou"'
Autor:
Tomohiro Yamaki, Shinichi Oka, Satoshi Iyama, Masanori Sasaki, Rie Onodera, Yuko Kataoka-Sasaki, Takahiro Namioka, Ai Namioka, Masahito Nakazaki, Mitsuhiro Takemura, Ryo Ukai, Takahiro Yokoyama, Yuichi Sasaki, Tatsuro Yamashita, Masato Kobayashi, Misako Yamaguchi, Marina Fukino, Taro Takazawa, Megumi Hayasaka, Takamitsu Owaku, Mika Funakura, Shinji Onodera, Yoichi M. Ito, Masayoshi Kobune, Junji Kato, Sumio Ishiai, Jeffery D. Kocsis, Masaru Odaki, Yasuo Iwadate, Shigeki Kobayashi, Osamu Honmou
Publikováno v:
Interdisciplinary Neurosurgery, Vol 36, Iss , Pp 101927- (2024)
Objective: This study explores safety, feasibility, and potential improvement in functional status after intravenous infusion of mesenchymal stem cells (MSCs) in chronic severe brain injury (BI) patients. Methods: An intravenous infusion of autologou
Externí odkaz:
https://doaj.org/article/625517512187496f8a86d181168f9d61
Publikováno v:
Spine Surgery and Related Research, Vol 7, Iss 4, Pp 319-326 (2023)
Since the 1990s, our group has been conducting basic research on regenerative medicine using various cell types to treat several central nervous system diseases, including spinal cord injury (SCI). We have reported many positive effects of the intrav
Externí odkaz:
https://doaj.org/article/3bfc640a4a4148bda3bd5a104301e848
Autor:
Shusaku Maeda, Takuji Kawamura, Masanori Sasaki, Kazuo Shimamura, Takashi Shibuya, Akima Harada, Osamu Honmou, Yoshiki Sawa, Shigeru Miyagawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Intravenous infusion of stem cells is a minimally invasive cellular delivery method, though a few have been reported in a critical limb-threatening ischemia (CLTI) animal model or patients. In the present study, we hypothesized that intraven
Externí odkaz:
https://doaj.org/article/d5936b8340c94f08a7c6dce3bba22870
Autor:
Takumi Hoshimaru, Naosuke Nonoguchi, Takuya Kosaka, Motomasa Furuse, Shinji Kawabata, Ryokichi Yagi, Yoshitaka Kurisu, Hideki Kashiwagi, Masahiro Kameda, Toshihiro Takami, Yuko Kataoka-Sasaki, Masanori Sasaki, Osamu Honmou, Ryo Hiramatsu, Masahiko Wanibuchi
Publikováno v:
Brain Sciences, Vol 13, Iss 10, p 1477 (2023)
Malignant glioma is a highly invasive tumor, and elucidating the glioma invasion mechanism is essential for developing novel therapies. We aimed to highlight actin alpha 2, smooth muscle (ACTA2) as potential biomarkers of brain invasion and distant r
Externí odkaz:
https://doaj.org/article/fc4a5aa9c73946c5a880e92d0b00b71c
Autor:
Hidetoshi Tabata, Masanori Sasaki, Yuko Kataoka-Sasaki, Nobuo Shinkai, Koji Ichihara, Naoya Masumori, Jeffery D. Kocsis, Osamu Honmou
Publikováno v:
BMC Urology, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Interstitial cystitis/bladder pain syndrome (IC/BPS) categorized with and without Hunner lesions is a condition that displays chronic pelvic pain related to the bladder with no efficacious treatment options. There are strong assoc
Externí odkaz:
https://doaj.org/article/a26989f9c6e448b0a5475d6b5788a594
Autor:
Shinichi Oka, Tomohiro Yamaki, Masanori Sasaki, Ryo Ukai, Mitsuhiro Takemura, Takahiro Yokoyama, Yuko Kataoka-Sasaki, Rie Onodera, Yoichi M Ito, Shigeki Kobayashi, Jeffery D Kocsis, Yasuo Iwadate, Osamu Honmou
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 7, p e37898 (2022)
BackgroundBrain injuries resulting from motor vehicle accidents and falls, as well as hypoxic insults and other conditions, are one of the leading causes of disability and death in the world. Current treatments are limited but include continuous reha
Externí odkaz:
https://doaj.org/article/17c74b82447e44dcadd5d6798575d762
Autor:
Hirotoshi Magota, Masanori Sasaki, Yuko Kataoka-Sasaki, Shinichi Oka, Ryo Ukai, Ryo Kiyose, Rie Onodera, Jeffery D. Kocsis, Osamu Honmou
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-4 (2021)
Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative fatal disorder in which motor neurons within the brain and spinal cord degenerate. A single infusion of mesenchymal stem cells (MSCs) delays disease progression by protecting motor n
Externí odkaz:
https://doaj.org/article/d27beaaedafa4575b1fa10bc19ba9cc9
Autor:
Mari Maeda-Yamamoto, Osamu Honmou, Masanori Sasaki, Akane Haseda, Hiroyo Kagami-Katsuyama, Toshihiko Shoji, Ai Namioka, Takahiro Namioka, Hirotoshi Magota, Shinichi Oka, Yuko Kataoka-Sasaki, Ryou Ukai, Mitsuhiro Takemura, Jun Nishihira
Publikováno v:
Nutrients, Vol 14, Iss 12, p 2446 (2022)
The purple-flesh potato (Solanum tuberosum L.) cultivar “Shadow Queen” (SQ) naturally contains anthocyanins. This randomized, double-blind, placebo-controlled study determines whether ingesting purple potatoes increases the number of mesenchymal
Externí odkaz:
https://doaj.org/article/6794c4789ff64ff290fccb0dbdd8b684
Autor:
Masahito Nakazaki, Shinichi Oka, Masanori Sasaki, Yuko Kataoka-Sasaki, Hiroshi Nagahama, Kazuo Hashi, Jeffery D. Kocsis, Osamu Honmou
Publikováno v:
Heliyon, Vol 6, Iss 12, Pp e05833- (2020)
Intravenous infusion of mesenchymal stem cells (MSCs) has been reported to provide therapeutic efficacy via microvascular remodeling in a spontaneously hypertensive rat. In this study, we demonstrate that intravenous infusion of MSCs increased the su
Externí odkaz:
https://doaj.org/article/5616ed1cb1b848d8bd07d8ef188ff84d
Autor:
Ryosuke, Hirota, Masanori, Sasaki, Yuko, Kataoka-Sasaki, Tsutomu, Oshigiri, Kota, Kurihara, Ryunosuke, Fukushi, Shinichi, Oka, Ryo, Ukai, Mitsunori, Yoshimoto, Jeffery D, Kocsis, Toshihiko, Yamashita, Osamu, Honmou
Publikováno v:
Journal of Neurotrauma. 39:1665-1677
Although limited spontaneous recovery occurs after spinal cord injury (SCI), current knowledge reveals that multiple forms of axon growth in spared axons can lead to circuit reorganization and a detour or relay pathways. This hypothesis has been deri