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pro vyhledávání: '"Osamu, Hayaishi"'
Autor:
Osamu Hayaishi
This book deals with molecular neurobiology based on neurochemical approaches and focuses on neural plasticity studied by neurophysiological methods. It offers discussions on prospects of neuroscience from the respective stances of the participants.
Autor:
Osamu Hayaishi, Yoshihiro Urade
Publikováno v:
Sleep Medicine Reviews. 15:411-418
Prostaglandin (PG) D2 is the most potent endogenous sleep-promoting substance. PGD2 is produced by lipocalin-type PGD synthase localized in the leptomeninges, choroid plexus, and oligodendrocytes in the brain, and is secreted into the cerebrospinal f
Publikováno v:
Current Topics in Medicinal Chemistry. 11:1047-1057
This paper presents an overview of the current knowledge about the role of adenosine in the sleep-wake regulation with a focus on adenosine in the central nervous system, regulation of adenosine levels, adenosine receptors, and manipulations of the a
Autor:
Osamu Hayaishi
Publikováno v:
Sleep and Biological Rhythms. 9:3-9
Sleep is perhaps one of the most important and yet least understood of the physiological functions of the brain. Sleep is essential for life, but we still cannot answer even the simplest questions about sleep, such as “what is sleep?,” “why do
Publikováno v:
Sleep and Biological Rhythms. 9:34-37
Histamine plays an important role in mediating wakefulness in mammals. Based on the findings from gene-manipulated mice, we provide several lines of evidence showing the roles of the histaminergic system in the somnogenic effects of prostaglandin (PG
Autor:
Yoshihiro Urade, Osamu Hayaishi
Publikováno v:
Future Neurology. 5:363-376
Prostaglandin (PG) D2 is the most potent endogenous sleep-promoting substance reported thus far. Its mechanism of action has been extensively studied at the molecular level. PGD2 is produced by lipocalin-type PGD synthase, which is predominantly loca
Autor:
Osamu Hayaishi
Publikováno v:
Journal of Biological Chemistry. 283:19165-19175
Autor:
Osamu Hayaishi
Oxygenases focuses on the processes, methodologies, technologies, and approaches involved in oxygenases, including its distribution in animals, plants, and microorganisms and its role in the metabolism of aromatic, cyclic, and aliphatic compounds. Th