Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Osami Yukawa"'
Autor:
Kouichi Tatsumi, Hiroko Hama-Inaba, Isamu Hayata, Hideo Tsuji, Osami Yukawa, Tetsuo Nakajima, Harumi Ohyama, Bing Wang
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 595:29-36
Protein kinase Cdelta (PKCdelta) has an important role in radiation-induced apoptosis. The expression and function of PKCdelta in radiation-induced apoptosis were assessed in a radiation-sensitive mouse thymic lymphoma cell line, 3SBH5, and its radio
Publikováno v:
International Journal of Radiation Biology. 81:681-688
To investigate changes in radical scavenging ability and lipid peroxidation in liver microsomal membranes and cooperative suppression of lipid peroxidation by microsomal and cytosolic radical scavengers, 24 h after whole-body, low-dose X-irradiation
Autor:
Harumi Ohyama, Isamu Hayata, Osami Yukawa, Tetsuo Nakajima, Hiroko Hama-Inaba, Bing Wang, Chihiro Azuma, Shuji Kojima
Publikováno v:
Radiation Research. 161:528-534
Protein kinase C (PKC; also known as PRKC) is known to be an important participant in radiation-induced apoptosis. However, its role is not fully clarified. Using 3SBH5 cells, which are radiation-sensitive thymic lymphoma cells, the involvement and f
Autor:
Osami Yukawa, S. Hayashi, Masanori Hatashita, Toshio Ohtsubo, Eiichi Kano, Zhao-Hui Jin, Hiroki Shioura, Hideki Matsumoto, Ryuhei Kitai, Yoshiya Furusawa
Publikováno v:
International Congress Series. 1236:295-298
To elucidate whether nitric oxide excreted from irradiated cells affects cellular radiosensitivity, we examined (a) the accumulation of inducible nitric oxide synthase, p53 and Hsp70, (b) the concentration of nitrite in the medium of cells after irra
Autor:
Misaki Kobayashi, Hideo Aoki, Yoshiya Furusawa, Ken Ohnishi, Osami Yukawa, Tetsuro Tamamoto, Akihisa Takahashi, Xinjiang Wang, Takeo Ohnishi, Hideki Matsumoto
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 47:489-494
Purpose: The aim of this study is to investigate the dependence of p53 -gene status on the radiation enhancement of thermosensitivity at different levels of linear energy transfer (LET). Methods and Materials: We used two kinds of human glioblastoma
Autor:
Osami Yukawa, H. Aoki, Ken Ohnishi, Tetsuro Tamamoto, X. Wang, Akira Tachibana, A. Takahashi, Yoshiya Furusawa, Hideki Matsumoto, K. Tsuji, Takeo Ohnishi, Yosuke Ejima
Publikováno v:
International Journal of Radiation Biology. 76:335-341
There have been no reports about the effects of heavy-ion beams on the expression of the WAF1 gene, although ionizing radiation such as y-rays and X-rays is well known to induce WAF1 (p21/CIP1/sdi1) gene expression in a p53-dependent manner. In the p
Publikováno v:
Journal of Radiation Research. 38:1-4
Publikováno v:
Geriatrics and Gerontology International. 4:S84-S86
Low to small doses of ionizing radiation conditionally show stimulatory effects in various cells and organisms, contrasting with detrimental effects induced at high doses. Radiation hormesis is defined as biopositive health effects, such as augmentat
Publikováno v:
International Congress Series. 1236:299-301
Murine thymic lymphoma cells and 3SBH5 are quite sensitive to X-rays and undergo apoptosis shortly after X-irradiation. Phorbol 12-myristate 13-acetate (PMA), an activator of protein kinase C (PKC), blocked the radiation-induced apoptosis in the 3SBH
Publikováno v:
Radiation research. 161(3)
The adaptive response is an important phenomenon in radiobiology. A study of the conditions essential for the induction of an adaptive response is of critical importance to understanding the novel biological defense mechanisms against the hazardous e