Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Osami Kanagawa"'
Autor:
Michio Tomura, Asako Sakaue-Sawano, Yoshiko Mori, Mitsuyo Takase-Utsugi, Akihiro Hata, Kenji Ohtawa, Osami Kanagawa, Atsushi Miyawaki
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73801 (2013)
A transgenic mouse line expressing Fucci (fluorescent ubiquitination-based cell-cycle indicator) probes allows us to monitor the cell cycle in the hematopoietic system. Two populations with high and low intensities of Fucci signals for Cdt1(30/120) a
Externí odkaz:
https://doaj.org/article/03ee1be2b13b406585f655de3a2ecea4
Autor:
Axel Patrice, Villani, Aurore, Rozieres, Benoît, Bensaid, Klara Kristin, Eriksson, Amandine, Mosnier, Floriane, Albert, Virginie, Mutez, Océane, Brassard, Tugba, Baysal, Mathilde, Tardieu, Omran, Allatif, Floriane, Fusil, Thibault, Andrieu, Denis, Jullien, Valérie, Dubois, Catherine, Giannoli, Henri, Gruffat, Marc, Pallardy, François-Loïc, Cosset, Audrey, Nosbaum, Osami, Kanagawa, Janet L, Maryanski, Daniel, Yerly, Jean-François, Nicolas, Marc, Vocanson
Publikováno v:
Science Advances
This study highlights the key role of polycytotoxic CD8+ T cells in the severity of toxic epidermal necrolysis.
Toxic epidermal necrolysis (TEN) is a life-threatening cutaneous adverse drug reaction. To better understand why skin symptoms are so
Toxic epidermal necrolysis (TEN) is a life-threatening cutaneous adverse drug reaction. To better understand why skin symptoms are so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::691a02aa1e565c2fce60d650b091e425
https://pubmed.ncbi.nlm.nih.gov/33741590
https://pubmed.ncbi.nlm.nih.gov/33741590
Autor:
Ana V Miletic, Daniel B Graham, Kumiko Sakata-Sogawa, Michio Hiroshima, Michael J Hamann, Saso Cemerski, Tracie Kloeppel, Daniel D Billadeau, Osami Kanagawa, Makio Tokunaga, Wojciech Swat
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6599 (2009)
BACKGROUND:T cell receptor (TCR) engagement leads to formation of signaling microclusters and induction of rapid and dynamic changes in the actin cytoskeleton, although the exact mechanism by which the TCR initiates actin polymerization is incomplete
Externí odkaz:
https://doaj.org/article/531bd18f9d744b3db2490e47f9786ecb
Autor:
Michio Tomura, Masaru Ishii, Yongwon Choi, Noriko Takegahara, Hyunsoo Kim, Atsushi Miyawaki, Asako Sakaue-Sawano, Hiroki Mizuno, Osami Kanagawa
Publikováno v:
The Journal of Biological Chemistry
Osteoclasts are specialized polyploid cells that resorb bone. Upon stimulation with receptor activator of nuclear factor-κB ligand (RANKL), myeloid precursors commit to becoming polyploid, largely via cell fusion. Polyploidization of osteoclasts is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd6d46dce0b89debb94e0c5fe4b84b4
https://doi.org/10.1074/jbc.m115.677427
https://doi.org/10.1074/jbc.m115.677427
Publikováno v:
The Journal of Immunology. 190:970-976
Several populations of memory T cells have been described that differ in their migration and function. In this study, we have identified a unique subset of memory T cells, which we have named recirculating memory T cells (TRCM). By exposing Kaede tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339f0a24bfc5214a473da0e63a03f227
https://doi.org/10.4049/jimmunol.1202805
https://doi.org/10.4049/jimmunol.1202805
Autor:
Gyohei Egawa, Jason G. Cyster, Herman Waldmann, Tetsuya Honda, Hideaki Tanizaki, Yoshiki Tokura, Osami Kanagawa, Yoshiki Miyachi, Kenji Kabashima, Takeshi Watanabe, Atsushi Otsuka, Michio Tomura, Shohei Hori
Tregs play an important role in protecting the skin from autoimmune attack. However, the extent of Treg trafficking between the skin and draining lymph nodes (DLNs) is unknown. We set out to investigate this using mice engineered to express the photo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c189b94ff6e5ca1fa41778fb1175273d
https://ora.ox.ac.uk/objects/uuid:626a04bb-64af-4ed1-84bc-de6ad49cc62c
https://ora.ox.ac.uk/objects/uuid:626a04bb-64af-4ed1-84bc-de6ad49cc62c
Autor:
Osami Kanagawa, Mitsuyo Takase, Sidonia Fagarasan, Ryuji Iida, Mikako Maruya, Satoshi Nishigami, Atsushi Miyawaki, Teruhiko Wakayama, Asako Sakaue-Sawano
Publikováno v:
International Immunology. 25:145-156
The transfer of nuclei of fully differentiated cells into enucleated oocytes is a well-recognized method for the generation of embryonic stem (ES) cells. Here, we demonstrate that nuclear transferred ES (NT-ES) cells can be established with high effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f68530204c09e4fac0e9a3fe313b5fa
https://doi.org/10.1093/intimm/dxs095
https://doi.org/10.1093/intimm/dxs095
Publikováno v:
Wound Repair and Regeneration. 20:A79-A82
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53f44c55fe3f627c6693234a6671ef90
https://doi.org/10.1111/j.1524-475x.2012.00838.x
https://doi.org/10.1111/j.1524-475x.2012.00838.x
Autor:
Osami Kanagawa, Teruhiko Wakayama, Keiichiro Suzuki, Sidonia Fagarasan, Mikako Maruya, Hanae Fujimoto, Michio Miyajima
Publikováno v:
Proceedings of the National Academy of Sciences. 108:722-727
B1 cells represent a distinct subset of B cells that produce most of the natural serum IgM and much of the gut IgA and function as an important component of early immune responses to pathogens. The development of B1 cells depends on the nuclear facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8429c97c81128cfbb6e6c88735365c67
https://doi.org/10.1073/pnas.1014697108
https://doi.org/10.1073/pnas.1014697108
Publikováno v:
The Journal of Immunology. 185:6041-6048
The trans presentation of IL-15 by cells expressing the specific high-affinity receptor α-chain (IL-15Rα) to cells expressing the signaling receptor β-chain and γ-chain is essential for the generation and maintenance of CD8 memory T cells, NK cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748e6025d7f7dc1bd2d32bdbdcd17662
https://doi.org/10.4049/jimmunol.0901834
https://doi.org/10.4049/jimmunol.0901834