Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Osama Sudah"'
Publikováno v:
Organic Process Research & Development. 16:204-213
Inline IR has been applied to evaluate the scale-up of processes that potentially generate hazardous diborane, hydrazoic acid, methyl chloride, or acetylene in the headspace of reactors. In addition, a new, simplified approach to calibrate the online
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af2239020bc9fec1e4c2ae5b065cc767
https://doi.org/10.1021/op200271b
https://doi.org/10.1021/op200271b
Autor:
Mark R. Smith, Osama Sudah, Steve Hammond, David J. Goldfarb, Marcos Llusa, Hanu Ramachandruni, Fernando J. Muzzio, Howard J. Stamato, Kurt Sturm
Publikováno v:
Industrial & Engineering Chemistry Research. 48:93-101
This paper examines the effect of three protocols with several units and blender parameters on the mitigation of active pharmaceutical ingredient (API) agglomeration in solid formulations. The three protocols either preblend API with a portion of exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfcbd51300f8555c59213a249b5c2334
https://doi.org/10.1021/ie8007055
https://doi.org/10.1021/ie8007055
Autor:
Christopher J. Welch, Glenn Spencer, Osama Sudah, Mirlinda Biba, Leonard William, Derek W. Henderson, Ross A. Miller
Publikováno v:
Chirality. 19:693-700
The modern use of preparative chromatography in pharmaceutical development is illustrated by the case of a recent preclinical candidate from these laboratories. The synthesis of the candidate employed a coupling of two enantiopure intermediates, each
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f71fa79e5fa24f35d8d42a06e2f01b
https://doi.org/10.1002/chir.20378
https://doi.org/10.1002/chir.20378
Autor:
Anant Vailaya, Vincent R. Capodanno, Peter Sajonz, Theresa K. Natishan, Roy Helmy, Firoz D. Antia, Lynette McPherson, Osama Sudah
Publikováno v:
Journal of Chromatography A. 1126:365-372
A gradient elution preparative chromatography method was developed for the recovery of the antibiotic ertapenem from crystallization mother-liquor streams. The preparative HPLC method that was developed on the lab-scale employs an analytical size col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db4d3030e1ebdea6ec42f38c3114904
https://doi.org/10.1016/j.chroma.2006.04.077
https://doi.org/10.1016/j.chroma.2006.04.077
Autor:
Aaron Moment, Todd D. Nelson, Osama Sudah, Paul Fernandez, Michael H. Kress, Matthew R. Hickey, Stephen D. Rodgers, Mahmoud S. Kaba, Shawn P. Allwein
Publikováno v:
Organic Process Research & Development. 9:764-767
A scalable process for a pilot plant synthesis of methyl 2-bromo-6-chlorobenzoate (1) is described. The strategy employed for the synthesis hinged on the esterification of the sterically encumbered parent acid produced through an o-lithiation/carboxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ee051f0a963a7f7c50896987a71e94
https://doi.org/10.1021/op0501444
https://doi.org/10.1021/op0501444
Publikováno v:
Journal of Chromatography A. 1079:80-91
Preparative chromatography was successfully employed to recover ertapenem from mother liquor streams. The recovery process involved concentration of mother liquor stream by evaporation, purification by reversed-phase preparative high-performance liqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40bde1a7c4150844bf090091f4c2512
https://doi.org/10.1016/j.chroma.2005.04.004
https://doi.org/10.1016/j.chroma.2005.04.004
Autor:
Marcos Llusa, Kurt Sturm, Osama Sudah, Howard Stamato, David J. Goldfarb, Hanu Ramachandruni, Steve Hammond, Mark R. Smith, Fernando J. Muzzio
Publikováno v:
Industrial & Engineering Chemistry Research; Jan2009, Vol. 48 Issue 1, p93-101, 9p