Zobrazeno 1 - 10
of 384
pro vyhledávání: '"Osama Gaber, And A."'
Autor:
Luke Kosinski, Eric Frey, Amanda Klein, Inish O'Doherty, Klaus Romero, Mark Stegall, Ilkka Helanterä, Ahmed Osama Gaber, William E. Fitzsimmons, Varun Aggarwal, Transplant Therapeutics Consortium (TTC)
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 9, Pp 1680-1690 (2023)
Abstract Kidney transplantation is the preferred treatment for individuals with end‐stage kidney disease. From a modeling perspective, our understanding of kidney function trajectories after transplantation remains limited. Current modeling of kidn
Externí odkaz:
https://doaj.org/article/7241a41580864d65a17bfe904e44574e
Autor:
Ashton A. Connor, MD, PhD, Max W. Adelman, MD, Constance M. Mobley, MD, PhD, Mozhgon Moaddab, PharmD, Alexandra J. Erhardt, MD, David E. Hsu, MSc, Elizabeth W. Brombosz, PhD, Mansi Sanghvi, MD, Yee Lee Cheah, MD, Caroline J. Simon, MD, Mark J. Hobeika, MD, Ashish S. Saharia, MD, David W. Victor, III, MD, Sudha Kodali, MD, Tamneet Basra, MD, Edward A. Graviss, PhD, Duc T. Nguyen, MD, PhD, Ahmed Elsaiey, MD, Linda W. Moore, PhD, Masayuki Nigo, MD, Ashley L. Drews, MD, Kevin A. Grimes, MD, Cesar A. Arias, MD, PhD, Xian C. Li, MD, PhD, A. Osama Gaber, MD, R. Mark Ghobrial, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 4, p e1590 (2024)
Background. The COVID-19 pandemic has led to an increase in SARS-CoV-2–test positive potential organ donors. The benefits of life-saving liver transplantation (LT) must be balanced against the potential risk of donor-derived viral transmission. Alt
Externí odkaz:
https://doaj.org/article/52873567970f4b91b1a294efdb791378
Autor:
Jesus Paez-Mayorga, Jocelyn Nikita Campa-Carranza, Simone Capuani, Nathanael Hernandez, Hsuan-Chen Liu, Corrine Ying Xuan Chua, Fernanda Paola Pons-Faudoa, Gulsah Malgir, Bella Alvarez, Jean A. Niles, Lissenya B. Argueta, Kathryn A. Shelton, Sarah Kezar, Pramod N. Nehete, Dora M. Berman, Melissa A. Willman, Xian C. Li, Camillo Ricordi, Joan E. Nichols, A. Osama Gaber, Norma S. Kenyon, Alessandro Grattoni
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Islet transplantation for type 1 diabetes management is hindered by the life-long need for immunosuppressive medications. Here, the authors report an islet encapsulation device with local anti-rejection drug release that achieves long-term diabetes r
Externí odkaz:
https://doaj.org/article/ef6eb5e65db74c5a8927a7416c908e0b
Qualifying a Novel Clinical Trial Endpoint (iBOX) Predictive of Long-Term Kidney Transplant Outcomes
Autor:
Amanda Klein, Alexandre Loupy, Mark Stegall, Ilkka Helanterä, Luke Kosinski, Eric Frey, Olivier Aubert, Gillian Divard, Kenneth Newell, Herwig-Ulf Meier-Kriesche, Roslyn Mannon, Thomas Dumortier, Varun Aggarwal, Jagdeep T. Podichetty, Inish O’Doherty, Ahmed Osama Gaber, William E. Fitzsimmons
Publikováno v:
Transplant International, Vol 36 (2023)
New immunosuppressive therapies that improve long-term graft survival are needed in kidney transplant. Critical Path Institute’s Transplant Therapeutics Consortium received a qualification opinion for the iBOX Scoring System as a novel secondary ef
Externí odkaz:
https://doaj.org/article/30625a9a0ea742bbb206416f92a9eb5a
Autor:
Elizabeth W. Brombosz, Linda W. Moore, Constance M. Mobley, Sudha Kodali, Ashish Saharia, Mark J. Hobeika, Ashton A. Connor, David W. Victor, Yee Lee Cheah, Caroline J. Simon, Ahmed Osama Gaber, Rafik Mark Ghobrial
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
BackgroundLiver retransplantation (reLT) has historically had inferior survival relative to primary liver transplant (LT). To improve outcomes after reLT, researchers have identified factors predicting overall (OS) and/or graft survival (GS) after re
Externí odkaz:
https://doaj.org/article/d6b0ca54f4544a6fbda1dc1abbd4463a
Autor:
Ashton A. Connor, MD, PhD, Howard J. Huang, MD, Constance M. Mobley, MD, PhD, Edward A. Graviss, MD, Duc T. Nguyen, MD, PhD, Ahmad Goodarzi, MD, Ashish Saharia, MD, Simon Yau, MD, Mark J. Hobeika, MD, Erik E. Suarez, MD, Mozhgon Moaddab, PharmD, Elizabeth W. Brombosz, PhD, Linda W. Moore, PhD, Stephanie G. Yi, MD, A. Osama Gaber, MD, Rafik Mark Ghobrial, MD, PhD
Publikováno v:
Transplantation Direct, Vol 9, Iss 5, p e1482 (2023)
Background. Combined liver–lung transplantation is an uncommon, although vital, procedure for patients with simultaneous end-stage lung and liver disease. The utility of lung–liver transplant has been questioned because of initial poor survival o
Externí odkaz:
https://doaj.org/article/a42d801093754a2fb0ebbf1b3d8cce55
Autor:
Knight, Richard J., Loucks-Devos, Jennifer, Khan, Naja A., Nguyen, Duc T., Graviss, Edward A., Eagar, Todd N., Patel, Samir J., Osama Gaber, A.
Publikováno v:
In Transplantation Proceedings July-August 2021 53(6):1865-1871
Autor:
Christine A. Beamish, PhD, A. Osama Gaber, MD, Daniel W. Fraga, MBA, Dale J. Hamilton, MD, Omaima M. Sabek, PhD
Publikováno v:
Transplantation Direct, Vol 8, Iss 10, p e1367 (2022)
Background. Islet and β-cell function is intrinsic to glucose homeostasis. Pancreatectomy and islet autotransplantation (PIAT) for chronic pancreatitis (CP) treatment is a useful model for assessing islet function in the absence of immune-suppressio
Externí odkaz:
https://doaj.org/article/67aaf6596c58465387c2fbbe2f89996c
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The transcriptional regulation of B-cell response to antigen stimulation is complex and involves an intricate network of dynamic signals from cytokines and transcription factors propagated from T-cell interaction. Long-term alloimmunity, in the setti
Externí odkaz:
https://doaj.org/article/b9f95df34e16428a87bc9e94fa28ce66
Autor:
Micaela Sandoval, Duc T Nguyen, Howard J Huang, Stephanie G Yi, R Mark Ghobrial, A Osama Gaber, Edward A Graviss
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279222 (2022)
BackgroundSolid organ transplant (SOT) recipients are at increased risk for morbidity and mortality from COVID-19 due to their immunosuppressed state and reduced immunogenicity from COVID-19 mRNA vaccines. This investigation examined the association
Externí odkaz:
https://doaj.org/article/9751a9d158c0427a946ce86ca51a9093