Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Osama Alsmadi"'
Autor:
Prashantha Hebbar, Rasheeba Nizam, Sumi Elsa John, Dinu Antony, Mohammad Dashti, Arshad Channanath, Azza Shaltout, Hessa Al-Khandari, Heikki A. Koistinen, Jaakko Tuomilehto, Osama Alsmadi, Thangavel Alphonse Thanaraj, Fahd Al-Mulla
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Type 1 diabetes (T1D) is characterized by the progressive destruction of pancreatic β-cells, leading to insulin deficiency and lifelong dependency on exogenous insulin. Higher estimates of heritability rates in monozygotic twins, followed b
Externí odkaz:
https://doaj.org/article/eb2a643ae53743f9b4beaaeb1e0a62cf
Autor:
Sawsan Mubarak, Osama Alsmadi, Abdelghani Tbakhi, Osama Abu Ata, Ala'a Hassan, Hadeel AlGhawrie
Publikováno v:
Immunity, Inflammation and Disease, Vol 11, Iss 11, Pp n/a-n/a (2023)
Abstract Introduction and Objective The emergence of the COVID‐19 pandemic raised questions about the interaction between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and other respiratory viruses. The objective of this study is
Externí odkaz:
https://doaj.org/article/8f7b6a5873064773905a307adbab7b89
Autor:
Mohamed Abu-Farha, Dhanya Madhu, Prashantha Hebbar, Anwar Mohammad, Arshad Channanath, Sina Kavalakatt, Nada Alam-Eldin, Fatima Alterki, Ibrahim Taher, Osama Alsmadi, Mohammad Shehab, Hossein Arefanian, Rasheed Ahmad, Thangavel Alphonse Thanaraj, Fahd Al-Mulla, Jehad Abubaker
Publikováno v:
Cells, Vol 12, Iss 21, p 2563 (2023)
Background: Angiopoietin-like protein 8 (ANGPTL8) is known to regulate lipid metabolism and inflammation. It interacts with ANGPTL3 and ANGPTL4 to regulate lipoprotein lipase (LPL) activity and with IKK to modulate NF-κB activity. Further, a single
Externí odkaz:
https://doaj.org/article/58af7644c19a46d09ac517ee0f9f76a1
Autor:
Mayada Abu Shanap, Maher Sughayer, Osama Alsmadi, Ismail Elzayat, Abeer Al-Nuirat, Abdelghani Tbakhi, Iyad Sultan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectivesWe aimed to study the outcomes, severity, and seroconversion post SARS-CoV-2 infection in immunocompromised children and adolescents treated at our center.MethodFor this observational study, all pediatric patients who had COVID-19 infection
Externí odkaz:
https://doaj.org/article/4e96a63ca5474e68aa87a55f382482b7
Autor:
Prashantha Hebbar, Rasheeba Nizam, Motasem Melhem, Fadi Alkayal, Naser Elkum, Sumi Elsa John, Jaakko Tuomilehto, Osama Alsmadi, Thangavel Alphonse Thanaraj
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 10, Pp 1951-1966 (2018)
Abnormal blood lipid levels are influenced by genetic and lifestyle/dietary factors. Although many genetic variants associated with blood lipid traits have been identified in Europeans, similar data in Middle Eastern populations are limited. We perfo
Externí odkaz:
https://doaj.org/article/729e23d292af49859a4a3deab60811fb
Autor:
Maha M. Hammad, Mohamed Abu-Farha, Prashantha Hebbar, Preethi Cherian, Irina Al Khairi, Motasem Melhem, Fadi Alkayal, Osama Alsmadi, Thangavel Alphonse Thanaraj, Fahd Al-Mulla, Jehad Abubaker
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Melanocortin 4 receptor (MC4R), a notable component of the melanocortin system, regulates appetite, body weight, and energy homeostasis. Genome-wide association studies have identified several MC4R variants associated with adiposity; of these, rs1778
Externí odkaz:
https://doaj.org/article/5206f2ff0dde4ce196a880986ead9c2d
Autor:
Massimo Mezzavilla, Sara Tomei, Fadi Alkayal, Motasem Melhem, Maisa M. Ali, Monira Al-Arouj, Abdullah Bennakhi, Osama Alsmadi, Naser Elkum
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-6 (2018)
Abstract Background Differences in the concentrations of circulating 25-hydroxyvitamin D [25(OH)D] are associated with a wide range of health outcomes; however, most studies on genetic variants that impact 25(OH)D levels have been conducted in Europe
Externí odkaz:
https://doaj.org/article/e0a684089e84442cb7ba77e2aa912599
Autor:
Rasheeba Nizam, Ebaa Al-Ozairi, Jo Max Goodson, Motesam Melhem, Lena Davidsson, Hessa Alkhandari, Ashraf Al Madhoun, Sara Shamsah, Malak Qaddoumi, Ghazi Alghanim, Nouf Alhasawi, Mohamed Abu-Farha, Jehad Abubaker, Ping Shi, Mor-Li Hartman, Mary Tavares, Milad Bitar, Hamad Ali, Hossein Arefanian, Sriraman Devarajan, Faisal Al-Refaei, Osama Alsmadi, Jaakko Tuomilehto, Fahd Al-Mulla
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/098e2e965a4242aea304bbf4ccf02e39
Autor:
Rasheeba Nizam, Ebaa Al-Ozairi, Jo Max Goodson, Motesam Melhem, Lena Davidsson, Hessa Alkhandari, Ashraf Al Madhoun, Sara Shamsah, Malak Qaddoumi, Ghazi Alghanim, Nouf Alhasawi, Mohamed Abu-Farha, Jehad Abubaker, Ping Shi, Mor-Li Hartman, Mary Tavares, Milad Bitar, Hamad Ali, Hossein Arefanian, Sriraman Devarajan, Faisal Al-Refaei, Osama Alsmadi, Jaakko Tuomilehto, Fahd Al-Mulla
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Caveolin-1 (CAV1) variants have been suggested to be associated with obesity and related metabolic disorders, but information based on human studies is limited. In the present study, we aimed to investigate the potential association between the CAV1
Externí odkaz:
https://doaj.org/article/9f2c18cab3db4466894fb8fcf7a07d86
Autor:
Sumi Elsa John, Gaurav Thareja, Prashantha Hebbar, Kazem Behbehani, Thangavel Alphonse Thanaraj, Osama Alsmadi
Publikováno v:
Genomics Data, Vol 3, Iss C, Pp 116-127 (2015)
Kuwaiti native population comprises three distinct genetic subgroups of Persian, “city-dwelling” Saudi Arabian tribe, and nomadic “tent-dwelling” Bedouin ancestry. Bedouin subgroup is characterized by presence of 17% African ancestry; it owes
Externí odkaz:
https://doaj.org/article/200b2463969f4bd4a3331c2716fb7938