Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Osama Albarbarawi"'
Autor:
Osama Albarbarawi
Publikováno v:
Medicinal & Analytical Chemistry International Journal. 7
Fast spread of COVID-19 worldwide causing unprecedented number of coronavirus infections, Scientist community are in race to control the disease by the development of both novel effective diagnostics strategies and effective therapies. Ultimately an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54dd1c7da5f9603e9694e048260489c5
https://doi.org/10.23880/macij-16000177
https://doi.org/10.23880/macij-16000177
Author Correction: The active site of O-GlcNAc transferase imposes constraints on substrate sequence
Autor:
Shalini Pathak, Jana Alonso, Marianne Schimpl, Karim Rafie, David E. Blair, Vladimir S. Borodkin, Alexander W. Schüttelkopf, Osama Albarbarawi, Daan M. F. van Aalten
Publikováno v:
Nature Structural & Molecular Biology. 30:564-564
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::913f22de9d5642f2f5b11375c4e08651
https://doi.org/10.1038/s41594-023-00945-5
https://doi.org/10.1038/s41594-023-00945-5
Autor:
Daan M. F. van Aalten, Megan A. Macnaughtan, David A. Robinson, Tonia Aristotelous, D.E. Blair, Xiaowei Zheng, Vladimir S. Borodkin, Andrew T. Ferenbach, Iva Navratilova, Marianne Schimpl, Alexander W. Schüttelkopf, Osama Albarbarawi
Publikováno v:
Nature chemical biology
Protein O-GlcNAcylation is an essential post-translational modification on hundreds of intracellular proteins in metazoa, catalyzed by O-GlcNAc transferase using unknown mechanisms of transfer and substrate recognition. Through crystallographic snaps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac26ad1965087441579796a026905ea
https://doi.org/10.1038/nchembio.1108
https://doi.org/10.1038/nchembio.1108
Autor:
David G. Campbell, Adel F. M. Ibrahim, Shalini Pathak, Osama Albarbarawi, Daan M. F. van Aalten, Vladimir S. Borodkin
Publikováno v:
The EMBO Journal. 31:1394-1404
Transforming growth factor (TGF)-β-activated kinase 1 (TAK1) is a key serine/threonine protein kinase that mediates signals transduced by pro-inflammatory cytokines such as transforming growth factor-β, tumour necrosis factor (TNF), interleukin-1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60eb787f1379b1ce339ad086059b8f61
https://doi.org/10.1038/emboj.2012.8
https://doi.org/10.1038/emboj.2012.8
Autor:
Charles McSharry, Alun Barton, Colin N. A. Palmer, Jeffrey T.-J. Huang, Douglas K. Miller, Giora Feuerstein, Osama Albarbarawi, Christal Grierson, Christopher J. Weir, Petra Rauchhaus, Martina Messow, Neil C. Thomson, Jeffrey Brady, Somnath Mukhopadhyay, Rekha Chaudhuri, Nicola Stevens
Publikováno v:
Huang, J T-J, Chaudhuri, R, Albarbarawi, O, Barton, A, Grierson, C, Rauchhaus, P, Weir, C J, Messow, M, Stevens, N, McSharry, C, Feuerstein, G, Mukhopadhyay, S, Brady, J, Palmer, C N A, Miller, D & Thomson, N C 2012, ' Clinical validity of plasma and urinary desmosine as biomarkers for chronic obstructive pulmonary disease ', Thorax, vol. 67, no. 6, pp. 502-508 . https://doi.org/10.1136/thoraxjnl-2011-200279
Thorax
Thorax
Background Although an increased concentration of degraded elastin products in patients with chronic obstructive pulmonary disease (CORD) has been reported for many years, its clinical validity and utility remain uncertain due to technical difficulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc65f2ffeaab05f5e6c035bfbbd9308
https://doi.org/10.1136/thoraxjnl-2011-200279
https://doi.org/10.1136/thoraxjnl-2011-200279
Autor:
D.E. Blair, Alexander W. Schüttelkopf, Marianne Schimpl, Daan M. F. van Aalten, Osama Albarbarawi, Karim Rafie, Shalini Pathak, Vladimir S. Borodkin, Jana Alonso
Publikováno v:
Nature structuralmolecular biology. 22(9)
O-GlcNAc transferase (OGT) glycosylates a diverse range of intracellular proteins with O-linked N-acetylglucosamine (O-GlcNAc), an essential and dynamic post-translational modification in metazoans. Although this enzyme modifies hundreds of proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef30ae6807ae1a57827603f234a97a4
https://pubmed.ncbi.nlm.nih.gov/26237509
https://pubmed.ncbi.nlm.nih.gov/26237509
Autor:
Daan M. F. van Aalten, Michael A. J. Ferguson, Wenxia Fang, Karina Mariño, Ramon Hurtado-Guerrero, Osama Albarbarawi, Cheng Jin, Olawale G. Raimi, Adel F. M. Ibrahim, Ting-Ting Du
Publikováno v:
Scopus-Elsevier
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Bioscience Reports, Vol 33, Iss 5, p e00063 (2013)
Bioscience Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Bioscience Reports, Vol 33, Iss 5, p e00063 (2013)
Bioscience Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
11 pags, 5 figs, 3 tabs
Synopsis Aspergillus fumigatus is the causative agent of IA (invasive aspergillosis) in immunocompromised patients. It possesses a cell wall composed of chitin, glucan and galactomannan, polymeric carbohydrates synthesize
Synopsis Aspergillus fumigatus is the causative agent of IA (invasive aspergillosis) in immunocompromised patients. It possesses a cell wall composed of chitin, glucan and galactomannan, polymeric carbohydrates synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8217806f50a6dea28945eef3170632
http://hdl.handle.net/10261/244786
http://hdl.handle.net/10261/244786
Autor:
Alun Barton, Rekha Chaudhuri, Osama Albarbarawi, Colin N. A. Palmer, Neil C. Thomson, Douglas K. Miller, Jeffrey T.-J. Huang, Graham Devereux, Charles McSharry
Publikováno v:
Bioanalysis. 5(16)
Background: Desmosine/isodesmosine (DES/IDS) is a promising biomarker for estimating activity of elastin degradation. Results/methodology: A stable isotope dilution LC–MS/MS method for measuring serum/plasma DES/IDS was developed and validated. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab2c99b9f4713004312d70443bcb37f
https://pubmed.ncbi.nlm.nih.gov/23937134
https://pubmed.ncbi.nlm.nih.gov/23937134
Autor:
Shalini, Pathak, Vladimir S, Borodkin, Osama, Albarbarawi, David G, Campbell, Adel, Ibrahim, Daan Mf, van Aalten
Publikováno v:
The EMBO Journal
O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release The protein kinase TAK1 plays an important role in pro-inflammatory cytokine signalling. Interleukin-1- and osmotic stress-induced O-GlcNAcylation of its regulatory subunit TAB1 is requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bce98c7473529047942cd83f37778596
https://pubmed.ncbi.nlm.nih.gov/22307082
https://pubmed.ncbi.nlm.nih.gov/22307082
Autor:
Osama Albarbarawi, Ajay Buddharaju, Zhaosheng Lin, Alun Barton, Douglas K. Miller, Jeffrey Brady, Colin N. A. Palmer, Eddie Takahashi, Jeffrey T.-J. Huang
Publikováno v:
Analytical chemistry. 82(9)
The current LC-MS based desmosine/isodesmosine (DES/IDS) assays may be unsatisfactory for clinical use due to lack of an appropriate internal standard or low throughput. A fast and reliable LC-MS method using a D(5)-DES as an internal standard for me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f555a211c8b76d8d6e15460d171b589a
https://pubmed.ncbi.nlm.nih.gov/20361748
https://pubmed.ncbi.nlm.nih.gov/20361748