Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Osama A. Arshad"'
Autor:
Alexandra Neaverson, Malin H. L. Andersson, Osama A. Arshad, Luke Foulser, Mary Goodwin-Trotman, Adam Hunter, Ben Newman, Minal Patel, Charlotte Roth, Tristan Thwaites, Helena Kilpinen, Matthew E. Hurles, Andrew Day, Sebastian S. Gerety
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Efficient and effective methods for converting human induced pluripotent stem cells into differentiated derivatives are critical for performing robust, large-scale studies of development and disease modelling, and for providing a source of cells for
Externí odkaz:
https://doaj.org/article/e475fa979c224d27a64c98a173d36582
Autor:
Jason E. McDermott, Osama A. Arshad, Vladislav A. Petyuk, Yi Fu, Marina A. Gritsenko, Therese R. Clauss, Ronald J. Moore, Athena A. Schepmoes, Rui Zhao, Matthew E. Monroe, Michael Schnaubelt, Chia-Feng Tsai, Samuel H. Payne, Chen Huang, Liang-Bo Wang, Steven Foltz, Matthew Wyczalkowski, Yige Wu, Ehwang Song, Molly A. Brewer, Mathangi Thiagarajan, Christopher R. Kinsinger, Ana I. Robles, Emily S. Boja, Henry Rodriguez, Daniel W. Chan, Bing Zhang, Zhen Zhang, Li Ding, Richard D. Smith, Tao Liu, Karin D. Rodland
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 5, Pp 100075- (2020)
Externí odkaz:
https://doaj.org/article/533e2f592347472b84fe6dd4510609f6
Autor:
Alexandra Neaverson, Malin H. L. Andersson, Osama A. Arshad, Luke Foulser, Mary Goodwin-Trotman, Adam Hunter, Ben Newman, Minal Patel, Charlotte Roth, Tristan Thwaites, Helena Kilpinen, Matthew E. Hurles, Andrew Day, Sebastian S. Gerety
Efficient and effective methods for converting human induced pluripotent stem cells (iPSC) into differentiated derivatives are critical for performing robust, large-scale studies of development and disease modelling, and for providing a source of cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fb170b281c3ec27c8518ba3b2413b7
https://doi.org/10.1101/2022.08.19.504404
https://doi.org/10.1101/2022.08.19.504404
Autor:
Maria O. Levitin, Lettie E Rawlins, Gabriela Sanchez-Andrade, Osama A. Arshad, Stephan C. Collins, Stephen J. Sawiak, Phillip H. Iffland, Malin H.L. Andersson, Caleb Bupp, Emma L. Cambridge, Eve L. Coomber, Ian Ellis, Johanna C. Herkert, Holly Ironfield, Logan Jory, Perrine F. Kretz, Sarina G. Kant, Alexandra Neaverson, Esther Nibbeling, Christine Rowley, Emily Relton, Mark Sanderson, Ethan M. Scott, Helen Stewart, Andrew Y. Shuen, John Schreiber, Liz Tuck, James Tonks, Thorkild Terkelsen, Conny van Ravenswaaij-Arts, Pradeep Vasudevan, Olivia Wenger, Michael Wright, Andrew Day, Adam Hunter, Minal Patel, Christopher J. Lelliott, Peter B. Crino, Binnaz Yalcin, Andrew Crosby, Emma L. Baple, Darren W. Logan, Matthew E. Hurles, Sebastian S. Gerety
KPTN-related disorder (KRD) is an autosomal recessive disorder associated with germline variants in KPTN (kaptin), a component of the mTOR regulatory complex KICSTOR. To gain further insights into the pathogenesis of KRD, we analysed mouse knockout a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4cbb0278fd0279fd1689af80476ba3a
https://doi.org/10.1101/2022.07.15.500213
https://doi.org/10.1101/2022.07.15.500213
Autor:
Vladislav A. Petyuk, Osama A. Arshad, Vincent G. Danna, Jason E. McDermott, Paul D. Piehowski, Karin D. Rodland, Tao Liu
Publikováno v:
Molecular & Cellular Proteomics. 18:S26-S36
Phosphorylation of proteins is a key way cells regulate function, both at the individual protein level and at the level of signaling pathways. Kinases are responsible for phosphorylation of substrates, generally on serine, threonine, or tyrosine resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9090b8a622e00ff210ab63982767eab3
https://doi.org/10.1074/mcp.ra119.001540
https://doi.org/10.1074/mcp.ra119.001540
Autor:
Mugimane G. Manjanatha, Shobhan Gaddameedhi, Hans P. A. Van Dongen, Justin G. Teeguarden, Kenneth I. Porter, Tarana Arman, Osama A. Arshad, Rajendra P. Gajula, Bala S C Koritala, Hugh D. Mitchell, Jason E. McDermott
Publikováno v:
J Pineal Res
Circadian disruption has been identified as a risk factor for health disorders such as obesity, cardiovascular disease, and cancer. Although epidemiological studies suggest an increased risk of various cancers associated with circadian misalignment d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0e3cedd06a72950ee358a6374b9462
https://doi.org/10.1111/jpi.12726
https://doi.org/10.1111/jpi.12726
Autor:
Karl K. Weitz, Shannon K. McWeeney, Athena A. Schepmoes, Chia-Feng Tsai, Tamilla Nechiporuk, Andy Kaempf, Cristina E. Tognon, Sunil K. Joshi, Sara J. C. Gosline, Emek Demir, Yi-Ting Wang, Julie A. Reisz, Brian J. Druker, Janét Pittsenbarger, Marina A. Gritsenko, Karin D. Rodland, Kevin Watanabe-Smith, Angelo D'Alessandro, Paul D. Piehowski, Tao Liu, Jamie Moon, Osama A. Arshad, Jason E. McDermott, Jeffrey W. Tyner, Özgün Babur, Joshua R. Hansen, Tujin Shi, Chelsea M. Hutchinson, Daniel Bottomly, Elie Traer, Thomas L. Fillmore
Publikováno v:
SSRN Electronic Journal.
Our study details the stepwise evolution of gilteritinib resistance in FLT3-mutated acute myeloid leukemia (AML). Early resistance is mediated by the bone marrow microenvironment, which protects residual leukemia cells. Removing these supportive extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdf70f0b2ec03bb37b36e7aa3b59fa84
https://doi.org/10.2139/ssrn.3771433
https://doi.org/10.2139/ssrn.3771433
Autor:
Charles D. Johnson, Aniruddha Datta, Noushin Ghaffari, Michael F. Criscitiello, Byung-Jun Yoon, John Thiltges, Osama A. Arshad, Hyundoo Jeong
Publikováno v:
IEEE/ACM Transactions on Computational Biology and Bioinformatics. 15:494-505
New de novo transcriptome assembly and annotation methods provide an incredible opportunity to study the transcriptome of organisms that lack an assembled and annotated genome. There are currently a number of de novo transcriptome assembly methods, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced77dcef9685fb2e7b29d639aa9183f
https://doi.org/10.1109/tcbb.2015.2446478
https://doi.org/10.1109/tcbb.2015.2446478
Autor:
Christopher R. Kinsinger, Yi Fu, Richard D. Smith, Karin Rodland, Vladislav A. Petyuk, Chia-Feng Tsai, Emily S. Boja, Osama A. Arshad, Henry Rodriguez, Ana Robles, Tao Liu, Li Ding, Daniel W. Chan, Bing Zhang, Zhen Zhang, Marina A. Gritsenko, Jason E. McDermott, Mathangi Thiagarajan, Samuel H. Payne
Publikováno v:
Cancer Research. 80:5123-5123
High-grade serous cancer (HGSC), the most prevalent histotype of ovarian cancer, has the lowest survival rates and is the leading cause of gynecological cancer-related deaths in the developed world. HGSC is characterized by the presence of nearly uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd77dbe7cde40c13f492190c111594ca
https://doi.org/10.1158/1538-7445.am2020-5123
https://doi.org/10.1158/1538-7445.am2020-5123
Autor:
Zhen Zhang, Tao Liu, Karin D. Rodland, Christopher R. Kinsinger, Ehwang Song, Molly Brewer, Osama A. Arshad, Steven M. Foltz, Emily S. Boja, Chen Huang, Liang-Bo Wang, Mathangi Thiagarajan, Ronald J. Moore, Marina A. Gritsenko, Michael Schnaubelt, Vladislav A. Petyuk, Samuel H. Payne, Yige Wu, Rui Zhao, Therese R. W. Clauss, Jason E. McDermott, Matthew E. Monroe, Athena A. Schepmoes, Henry Rodriguez, Richard D. Smith, Chia-Feng Tsai, Daniel W. Chan, Bing Zhang, Yi Fu, Matthew A. Wyczalkowski, Li Ding, Ana I. Robles
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 1, Pp 100004-(2020)
Cell reports. Medicine
Cell Reports Medicine, Vol 1, Iss 5, Pp 100075-(2020)
Cell reports medicine
Cell reports. Medicine
Cell Reports Medicine, Vol 1, Iss 5, Pp 100075-(2020)
Cell reports medicine
SUMMARY In the absence of a dominant driving mutation other than uniformly present TP53 mutations, deeper understanding of the biology driving ovarian high-grade serous cancer (HGSC) requires analysis at a functional level, including post-translation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06eeb34b8f2fc4bf29a90a7c8abbeef3
https://doi.org/10.1016/j.xcrm.2020.100075
https://doi.org/10.1016/j.xcrm.2020.100075