Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Osaid T, Almeanazel"'
Autor:
Hamad S Alyami, Mohamed A. Ibrahim, Mohammad H. Alyami, Eman Z Dahmash, Osaid T. Almeanazel, Thamer S Algahtani, Fars Alanazi, Doaa H. Alshora
Publikováno v:
Saudi Pharmaceutical Journal, Vol 29, Iss 5, Pp 478-486 (2021)
The delivery of antihistaminic agents via the oral route is problematic, especially for elderly patients. This study aimed to develop a sublingual formulation of promethazine hydrochloride by direct compression, and to mask its intensely bitter taste
Externí odkaz:
https://doaj.org/article/ab54c445d124499996507bee3d1f426b
Autor:
Sultan M. Alshehri, Faiyaz Shakeel, Mohamed A. Ibrahim, Ehab M. Elzayat, Mohammad Altamimi, Kazi Mohsin, Osaid T. Almeanazel, Musaed Alkholief, Abdullah Alshetaili, Bader Alsulays, Fars K. Alanazi, Ibrahim A. Alsarra
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 2, Pp 264-273 (2019)
Apigenin (APG) is a poorly soluble bioactive compound/nutraceutical which shows poor bioavailability upon oral administration. Hence, the objective of this research work was to develop APG solid dispersions (SDs) using different techniques with the e
Externí odkaz:
https://doaj.org/article/a6c39103971b4d6086f0240a011c798c
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200218 (2018)
PURPOSE:Rosuvastatin calcium (ROSCa) is a poorly soluble drug with bioavailability not exceeding 20%. Decreasing the particle size may enhance its solubility, dissolution rate and bioavailability. Therefore, the aim of the current study is to prepare
Externí odkaz:
https://doaj.org/article/d4652ec52b05432c8b791e72e92dc572
Autor:
Doaa H. Alshora, Eman Zmaily Dahmash, Mohamed Ibrahim, Thamer S Algahtani, Mohammad H. Alyami, Fars K. Alanazi, Osaid T. Almeanazel, Hamad S. Alyami
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 5, Pp 478-486 (2021)
Saudi Pharmaceutical Journal, Vol 29, Iss 5, Pp 478-486 (2021)
The delivery of antihistaminic agents via the oral route is problematic, especially for elderly patients. This study aimed to develop a sublingual formulation of promethazine hydrochloride by direct compression, and to mask its intensely bitter taste
Autor:
Lubna Y. Ashri, Osaid T. Almeanazel, Doaa H. Alshora, Amal El Sayeh F. Abou El Ela, Essam Ezzeldin, Mohamed Ibrahim, Shaikha Alsaif
Publikováno v:
Pharmaceutical Development and Technology. 25:845-854
Pioglitazone (PGZ) is an oral antidiabetic agent that increases cell resistance to insulin, thereby decreasing blood glucose levels. PGZ is a class II drug. Because of its pH-dependent solubility, it precipitates at the intestinal pH, resulting in an
Autor:
Faiyaz Shakeel, Ehab A. Fouad, Mohammed Alahmed, Ahmad T. Almnaizel, Ibrahim A. Alsarra, Fars K. Alanazi, Doaa H. Alshora, Osaid T. Almeanazel
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 28, Iss 5, Pp 565-573 (2020)
Saudi Pharmaceutical Journal, Vol 28, Iss 5, Pp 565-573 (2020)
Obesity is a metabolic disease that affects all ages; it is considered life-threatening condition as it leads to fatal complications such as; cardiovascular diseases and diabetes. The therapeutic options include; life-style modifications, pharmacothe
Publikováno v:
International Journal of Nanomedicine. 14:4625-4636
Purpose Rosuvastatin calcium (ROSCa) nanoparticles were fabricated by planetary ball mill to enhance ROSCa dissolution rate and bioavailability. Methods Milling time factors (milling cycle time and number as well as pause time) were explored. The eff
Autor:
Mohamed Ibrahim, Ehab M. Elzayat, Faiyaz Shakeel, Osaid T. Almeanazel, Abdullah S. Alshetaili, Musaed Alkholief, Ibrahim A. Alsarra, Fars K. Alanazi, Kazi Mohsin, Mohammad A. Altamimi, Sultan Alshehri, Bader B. Alsulays
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 2, Pp 264-273 (2019)
Apigenin (APG) is a poorly soluble bioactive compound/nutraceutical which shows poor bioavailability upon oral administration. Hence, the objective of this research work was to develop APG solid dispersions (SDs) using different techniques with the e
Autor:
Doaa H, Alshora, Shaikha, Alsaif, Mohamed A, Ibrahim, Essam, Ezzeldin, Osaid T, Almeanazel, Amal El Sayeh, Abou El Ela, Lubna Y, Ashri
Publikováno v:
Pharmaceutical development and technology. 25(7)
Pioglitazone (PGZ) is an oral antidiabetic agent that increases cell resistance to insulin, thereby decreasing blood glucose levels. PGZ is a class II drug. Because of its pH-dependent solubility, it precipitates at the intestinal pH, resulting in an
Autor:
Michael A. Repka, Mohammad A. Altamimi, Gamal A. Shazly, Bader B. Alsulays, Abdullah S. Alshetaili, Ahmed Alalaiwe, Faiyaz Shakeel, Mohsin Kazi, Ehab M. Elzayat, Bjad K. Almutairy, Osaid T. Almeanazel, Sultan Alshehri
Publikováno v:
Drug development and industrial pharmacy. 45(10)
Mefenamic acid (MA) has been reported as a weakly soluble drug which presents weak in vivo absorption upon oral administration using conventional formulations. Solid dispersions (SDs) have been inv...