Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Autor: Couch, F.J., Gaudet, M.M., Antoniou, A.C., Ramus, S.J., Kuchenbaecker, K.B., Soucy, P., Beesley, J., Chen, X.Q., Wang, X.S., Kirchhoff, T., McGuffog, L., Barrowdale, D., Lee, A., Healey, S., Sinilnikova, O.M., Andrulis, I.L., Ozcelik, H., Mulligan, A.M., Thomassen, M., Gerdes, A.M., Jensen, U.B., Skytte, A.B., Kruse, T.A., Caligo, M.A., Wachenfeldt, A. von, Barbany-Bustinza, G., Loman, N., Soller, M., Ehrencrona, H., Karlsson, P., Nathanson, K.L., Rebbeck, T.R., Domchek, S.M., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Zlowocka, E., Huzarski, T., Byrski, T., Gronwald, J., Cybulski, C., Gorski, B., Osorio, A., Duran, M., Tejada, M.I., Benitez, J., Hamann, U., Hogervorst, F.B.L., Os, T.A. van, Leeuwen, F.E. van, Meijers-Heijboer, H.E.J., Wijnen, J., Blok, M.J., Kets, M., Hooning, M.J., Oldenburg, R.A., Ausems, M.G.E.M., Peock, S., Frost, D., Ellis, S.D., Platte, R., Fineberg, E., Evans, D.G., Jacobs, C., Eeles, R.A., Adlard, J., Davidson, R., Eccles, D.M., Cole, T., Cook, J., Paterson, J., Brewer, C., Douglas, F., Hodgson, S.V., Morrison, P.J., Walker, L., Porteous, M.E., Kennedy, M.J., Side, L.E., Bove, B., Godwin, A.K., Stoppa-Lyonnet, D., Fassy-Colcombet, M., Castera, L., Cornelis, F., Mazoyer, S., Leone, M., Boutry-Kryza, N., Bressac-de Paillerets, B., Caron, O., Pujol, P., Coupier, I., Delnatte, C., Akloul, L., Lynch, H.T., Snyder, C.L., Buys, S.S., Daly, M.B., Terry, M., Chung, W.K., John, E.M., Miron, A., Southey, M.C., Hopper, J.L., Goldgar, D.E., Singer, C.F., Rappaport, C., Tea, M.K.M., Fink-Retter, A., Hansen, T.V.O., Nielsen, F.C., Arason, A., Vijai, J., Shah, S., Sarrel, K., Robson, M.E., Piedmonte, M., Phillips, K., Basil, J., Rubinstein, W.S., Boggess, J., Wakeley, K., Ewart-Toland, A., Montagna, M., Agata, S., Imyanitov, E.N., Isaacs, C., Janavicius, R., Lazaro, C., Blanco, I., Feliubadalo, L., Brunet, J., Gayther, S.A., Pharoah, P.P.D., Odunsi, K.O., Karlan, B.Y., Walsh, C.S., Olah, E., Teo, S.H., Ganz, P.A., Beattie, M.S., Rensburg, E.J. van, Dorfling, C.M., Diez, O., Kwong, A., Schmutzler, R.K., Wappenschmidt, B., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Heidemann, S., Niederacher, D., Preisler-Adams, S., Gadzicki, D., Varon-Mateeva, R., Deissler, H., Gehrig, A., Sutter, C., Kast, K., Fiebig, B., Heinritz, W., Caldes, T., Hoya, M. de la, Muranen, T.A., Nevanlinna, H., Tischkowitz, M., Spurdle, A.B., Neuhausen, S.L., Ding, Y.C., Lindor, N.M., Fredericksen, Z., Pankratz, V.S., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Barile, M., Bernard, L., Viel, A., Giannini, G., Varesco, L., Radice, P., Greene, M.H., Mai, P.L., Easton, D.F., Chenevix-Trench, G., Offit, K., Simard, J., OCGN, SWE-BRCA, HEBON, EMBRACE, GEMO Study Collaborators, kConFab Investigators, Consortium Investigators Modifiers

Publikováno v: Couch, F J, Gaudet, M M, Antoniou, A C, Ramus, S J, Kuchenbaecker, K B, Soucy, P, Beesley, J, Chen, X Q, Wang, X S, Kirchhoff, T, McGuffog, L, Barrowdale, D, Lee, A, Healey, S, Sinilnikova, O M, Andrulis, I L, Ozcelik, H, Mulligan, A M, Thomassen, M, Gerdes, A M, Jensen, U B, Skytte, A B, Kruse, T A, Caligo, M A, von Wachenfeldt, A, Barbany-Bustinza, G, Loman, N, Soller, M, Ehrencrona, H, Karlsson, P, Nathanson, K L, Rebbeck, T R, Domchek, S M, Jakubowska, A, Lubinski, J, Jaworska, K, Durda, K, Zlowocka, E, Huzarski, T, Byrski, T, Gronwald, J, Cybulski, C, Gorski, B, Osorio, A, Duran, M, Tejada, M I, Benitez, J, Hamann, U, Hogervorst, F B L, Os, T A, van Leeuwen, F E, Meijers-Heijboer, E J, van Wijnen, J, Blok, M J, Kets, M, Hooning, M J, Oldenburg, R A, Ausems, M G E M, Peock, S, Frost, D, Ellis, S D, Platte, R, Fineberg, E, Evans, D G, Jacobs, C, Eeles, R A, Adlard, J, Davidson, R, Eccles, D M, Cole, T, Cook, J, Paterson, J, Brewer, C, Douglas, F, Hodgson, SV, Morrison, P J, Walker, L, Porteous, M E, Kennedy, M J, Side, L E, Bove, B, Godwin, A K, Stoppa-Lyonnet, D, Fassy-Colcombet, M, Castera, L, Cornelis, F, Mazoyer, S, Leone, M, Boutry-Kryza, N, Bressac-de Paillerets, B, Caron, O, Pujol, P, Coupier, I, Delnatte, C, Akloul, L, Lynch, H T, Snyder, C L, Buys, S S & Daly, M B 2012, ' Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers ', Cancer Epidemiology Biomarkers and Prevention, vol. 21, no. 4, pp. 645-657 . https://doi.org/10.1158/1055-9965.EPI-11-0888
Couch, F J, Gaudet, M M, Antoniou, A C, Ramus, S J, Kuchenbaecker, K B, Soucy, P, Beesley, J, Chen, X, Wang, X, Kirchhoff, T, McGuffog, L, Barrowdale, D, Lee, A, Healey, S, Sinilnikova, O M, Andrulis, I L, Ozcelik, H, Mulligan, A M, Thomassen, M, Gerdes, A-M, Jensen, U B, Skytte, A-B, Kruse, T A, Caligo, M A, von Wachenfeldt, A, Barbany-Bustinza, G, Loman, N, Soller, M, Ehrencrona, H, Karlsson, P, Nathanson, K L, Rebbeck, T R, Domchek, S M, Jakubowska, A, Lubinski, J, Jaworska, K, Durda, K, Zlowocka, E, Huzarski, T, Byrski, T, Gronwald, J, Cybulski, C, Górski, B, Osorio, A, Durán, M, Tejada, M I, Benitez, J, Hamann, U, Hogervorst, F B L, van Os, T A & OCGN 2012, ' Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers ', Cancer Epidemiology, Biomarkers & Prevention, vol. 21, no. 4, pp. 645-57 . https://doi.org/10.1158/1055-9965.EPI-11-0888
Cancer Epidemiology Biomarkers and Prevention, 21(4), 645-657. American Association for Cancer Research Inc.
Cancer Epidemiology Biomarkers & Prevention; Vol 21
Cancer Epidemiology, Biomarkers and Prevention, 21(4), 645-657
Cancer Epidemiology, Biomarkers & Prevention, 21, 4, pp. 645-57
Digital.CSIC. Repositorio Institucional del CSIC
instname
Couch, F J, Gaudet, M M, Antoniou, A C, Ramus, S J, Kuchenbaecker, K B, Soucy, P, Beesley, J, Chen, X, Wang, X, Kirchhoff, T, McGuffog, L, Barrowdale, D, Lee, A R, Healey, S, Sinilnikova, O M, Andrulis, I L, Ozcelik, H, Mulligan, A M, Thomassen, M, Gerdes, A-M A, Jensen, U B, Skytte, A-B S, Kruse, T A, Caligo, M A, von Wachenfeldt, A, Barbany-Bustinza, G, Loman, N, Soller, M, Ehrencrona, H, Karlsson, P W, Nathanson, K L, Rebbeck, T R, Domchek, S M, Jakubowska, A, Lubinski, J, Jaworska, K, Durda, K, Zlowocka, E, Huzarski, T, Byrski, T, Gronwald, J, Cybulski, C, Górski, B, Osorio, A, Durán, M, Tejada, M I, Benitez, J, Hamann, U, Hogervorst, F B L, van Os, T A & OCGN 2012, ' Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers ', Cancer Epidemiology, Biomarkers & Prevention, vol. 21, no. 4, pp. 645-57 . https://doi.org/10.1158/1055-9965.EPI-11-0888
Cancer Epidemiology Biomarkers & Prevention, 21(4), 645-657. American Association for Cancer Research Inc.
Cancer Epidemiology, Biomarkers & Prevention, 21, 645-57
Cancer epidemiology, biomarkers & prevention, 21(4), 645-657. American Association for Cancer Research Inc.

PMCID: PMC3319317.-- et al.
[Background]: Genome-wide association studies (GWAS) identified variants at 19p13.1 and ZNF365 (10q21.2) as risk factors for breast cancer among BRCA1 and BRCA2 mutation carriers, respectively. We explored association

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b949799806fed1689a9d24c254b3c62
https://research.vumc.nl/en/publications/f7b6f7f2-aac8-4050-a221-f53efa006269

Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Autor: Engel, C., Versmold, B., Wappenschmidt, B., Simard, J., Easton, D.F., Peock, S., Cook, M., Oliver, C., Frost, D., Mayes, R., Evans, D.G., Eeles, R., Paterson, J., Brewer, C., McGuffog, L., Antoniou, A.C., Stoppa-Lyonnet, D., Sinilnikova, O.M., Barjhoux, L., Frenay, M., Michel, C., Leroux, D., Dreyfus, H., Toulas, C., Gladieff, L., Uhrhammer, N., Bignon, Y.J., Meindl, A., Arnold, N., Varon-Mateeva, R., Niederacher, D., Preisler-Adams, S., Kast, K., Deissler, H., Sutter, C., Gadzicki, D., Chenevix-Trench, G., Spurdle, A.B., Chen, X.Q., Beesley, J., Olsson, H., Kristoffersson, U., Ehrencrona, H., Liljegren, A., Luijt, R.B. van der, Os, T.A. van, Leeuwen, F.E. van, Domchek, S.M., Rebbeck, T.R., Nathanson, K.L., Osorio, A., Cajal, T.R.Y., Konstantopoulou, I., Benitez, J., Friedman, E., Kaufman, B., Laitman, Y., Mai, P.L., Greene, M.H., Nevanlinna, H., Aittomaki, K., Szabo, C.I., Caldes, T., Couch, F.J., Andrulis, I.L., Godwin, A.K., Hamann, U., Schmutzler, R.K., Epidemiological Study Familial Bre, Kathleen Cuningham Fdn Consortium, Sweden SWE-BRCA, Hereditary Breast Ovarian Canc Grp, Consortium Investigators Modifiers

Publikováno v: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology; 19, pp 2859-2868 (2010)
Cancer Epidemiology, Biomarkers & Prevention, 19, 2859-68
Cancer Epidemiology Biomarkers & Prevention, 19(11), 2859-2868. American Association for Cancer Research Inc.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Cancer epidemiology, biomarkers & prevention, 19(11), 2859-2868. American Association for Cancer Research Inc.
Cancer Epidemiology, Biomarkers and Prevention, 19(11), 2859-2868
Cancer Epidemiology Biomarkers and Prevention, 19(11), 2859-2868. American Association for Cancer Research Inc.
Engel, C, Versmold, B, Wappenschmidt, B, Simard, J, Easton, D F, Peock, S, Cook, M, Oliver, C, Frost, D, Mayes, R, Evans, D G, Eeles, R, Paterson, J, Brewer, C, McGuffog, L, Antoniou, A C, Stoppa-Lyonnet, D, Sinilnikova, O M, Barjhoux, L, Frenay, M, Michel, C, Leroux, D, Dreyfus, H, Toulas, C, Gladieff, L, Uhrhammer, N, Bignon, Y J, Meindl, A, Arnold, N, Varon-Mateeva, R, Niederacher, D, Preisler-Adams, S, Kast, K, Deissler, H, Sutter, C, Gadzicki, D, Chenevix-Trench, G, Spurdle, A B, Chen, X Q, Beesley, J, Olsson, H, Kristoffersson, U, Ehrencrona, H, Liljegren, A, van der Luijt, R B, Os, T A, van Leeuwen, F E, Domchek, S M, Rebbeck, T R, Nathanson, K L, Osorio, A, Cajal, T R Y, Konstantopoulou, I, Benitez, J, Friedman, E, Kaufman, B, Laitman, Y, Mai, P L, Greene, M H, Nevanlinna, H, Aittomaki, K, Szabo, C I, Caldes, T, Couch, F J, Andrulis, I L, Godwin, A K, Hamann, U & Schmutzler, R K 2010, ' Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers ', Cancer Epidemiology Biomarkers and Prevention, vol. 19, no. 11, pp. 2859-2868 . https://doi.org/10.1158/1055-9965.EPI-10-0517
Cancer Epidemiology, Biomarkers & Prevention, 19, 11, pp. 2859-68

Background: The genes caspase-8 (CASP8) and caspase-10 (CASP10) functionally cooperate and play a key role in the initiation of apoptosis. Suppression of apoptosis is one of the major mechanisms underlying the origin and progression of cancer. Previo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b194bf23b5a5ed942587889b64219a4b
https://lup.lub.lu.se/record/1710693