Investigation of α-glucosidase and α-amylase inhibitory effects of phenoxy chalcones and molecular modeling studies.

Autor: Kurşun-Aktar BS; Department of Hair Care and Beauty Services, Yeşilyurt Vocational School, Malatya Turgut Özal University, Malatya, Turkey., Adem Ş; Department of Chemistry, Faculty of Sciences, Çankırı Karatekin University, Çankırı, Turkey., Tatar-Yilmaz G; Department of Biostatistics and Medical Informatics, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey., Hameed ZAH; Department of Chemistry, Faculty of Sciences, Çankırı Karatekin University, Çankırı, Turkey., Oruç-Emre EE; Department of Chemistry, Faculty of Art and Sciences, Gaziantep University, Gaziantep, Turkey.

Publikováno v: Journal of molecular recognition : JMR [J Mol Recognit] 2023 Nov; Vol. 36 (11), pp. e3061. Date of Electronic Publication: 2023 Sep 18.

Chalcones bearing nitrogen-containing heterocyclics as multi-targeted inhibitors: Design, synthesis, biological evaluation and molecular docking studies.

Autor: Sıcak Y; Department of Medicinal and Aromatic Plants, Köyceğiz Vocational School, Muğla Sıtkı Koçman University, Muğla, Turkey., Kekeçmuhammed H; Department of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Turkey., Karaküçük-İyidoğan A; Department of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Turkey., Taşkın-Tok T; Department of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Turkey.; Institute of Health Sciences, Department of Bioinformatics and Computational Biology, Gaziantep University, Gaziantep, Turkey., Oruç-Emre EE; Department of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Turkey., Öztürk M; Department of Chemistry, Faculty of Sciences, Muğla Sıtkı Koçman University, Muğla, Turkey.

Publikováno v: Journal of molecular recognition : JMR [J Mol Recognit] 2023 Jul; Vol. 36 (7), pp. e3020. Date of Electronic Publication: 2023 May 05.

Novel fluorine-containing chiral hydrazide-hydrazones: Design, synthesis, structural elucidation, antioxidant and anticholinesterase activity, and in silico studies.

Autor: Sıcak Y; Köyceğiz Vocational School, Muğla Sıtkı Koçman University, Muğla, Turkey., Oruç-Emre EE; Faculty of Science and Arts, Department of Chemistry, Gaziantep University, Gaziantep, Turkey., Öztürk M; Faculty of Science, Department of Chemistry, Muğla Sıtkı Koçman University, Muğla, Turkey., Taşkın-Tok T; Faculty of Science and Arts, Department of Chemistry, Gaziantep University, Gaziantep, Turkey., Karaküçük-Iyidoğan A; Faculty of Science and Arts, Department of Chemistry, Gaziantep University, Gaziantep, Turkey.

Publikováno v: Chirality [Chirality] 2019 Aug; Vol. 31 (8), pp. 603-615. Date of Electronic Publication: 2019 Jun 20.

Synthesis, Biological Evaluation and Ligand Based Pharmacophore Modeling of New Aromatic Thiosemicarbazones as Potential Anticancer Agents.

Autor: Karaküçük-İyidoğan A; 1Department of Chemistry, Gaziantep University, 27310 Gaziantep, Turkey., Aydınöz B; 1Department of Chemistry, Gaziantep University, 27310 Gaziantep, Turkey., Taşkın-Tok T; 1Department of Chemistry, Gaziantep University, 27310 Gaziantep, Turkey., Oruç-Emre EE; 1Department of Chemistry, Gaziantep University, 27310 Gaziantep, Turkey., Balzarini J; 2Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium.

Publikováno v: Pharmaceutical chemistry journal [Pharm Chem J] 2019; Vol. 53 (2), pp. 139-149. Date of Electronic Publication: 2019 May 15.

New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors.

Autor: Karaman N; Department of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Turkey., Sıcak Y; Department of Herbal and Animal Production, Köyceğiz Vocational School, Muğla Sıtkı Koçman University, Muğla, Turkey; Department of Chemistry, Faculty of Sciences, Muğla Sıtkı Koçman University, Muğla, Turkey., Taşkın-Tok T; Department of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Turkey., Öztürk M; Department of Chemistry, Faculty of Sciences, Muğla Sıtkı Koçman University, Muğla, Turkey., Karaküçük-İyidoğan A; Department of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Turkey., Dikmen M; Department of Pharmacology, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey., Koçyiğit-Kaymakçıoğlu B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Marmara University, İstanbul, Turkey., Oruç-Emre EE; Department of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Turkey. Electronic address: oruc@gantep.edu.tr.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2016 Nov 29; Vol. 124, pp. 270-283. Date of Electronic Publication: 2016 Aug 20.