Membrane Particles Derived From Adipose Tissue Mesenchymal Stromal Cells Improve Endothelial Cell Barrier Integrity.

Autor: Merino A; Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands., Sablik M; Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands., Korevaar SS; Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands., López-Iglesias C; Microscopy CORE Lab, Maastricht Multimodal Molecular Imaging Institute, FHML Maastricht University, Maastricht, Netherlands., Ortiz-Virumbrales M; Takeda Madrid, Cell Therapy Technology Center, Madrid, Spain., Baan CC; Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands., Lombardo E; Takeda Madrid, Cell Therapy Technology Center, Madrid, Spain., Hoogduijn MJ; Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Apr 07; Vol. 12, pp. 650522. Date of Electronic Publication: 2021 Apr 07 (Print Publication: 2021).

Human adipose mesenchymal stem cells modulate myeloid cells toward an anti-inflammatory and reparative phenotype: role of IL-6 and PGE2.

Autor: Ortiz-Virumbrales M; Takeda Madrid, Cell Therapy Technology Center, Tres Cantos, Spain. maitane.ortiz@takeda.com., Menta R; Takeda Madrid, Cell Therapy Technology Center, Tres Cantos, Spain., Pérez LM; Takeda Madrid, Cell Therapy Technology Center, Tres Cantos, Spain., Lucchesi O; Takeda Madrid, Cell Therapy Technology Center, Tres Cantos, Spain., Mancheño-Corvo P; Takeda Madrid, Cell Therapy Technology Center, Tres Cantos, Spain., Avivar-Valderas Á; Takeda Madrid, Cell Therapy Technology Center, Tres Cantos, Spain., Palacios I; Takeda Madrid, Cell Therapy Technology Center, Tres Cantos, Spain., Herrero-Mendez A; Takeda Madrid, Cell Therapy Technology Center, Tres Cantos, Spain., Dalemans W; TiGenix NV, Leuven, Belgium., de la Rosa O; Takeda Madrid, Cell Therapy Technology Center, Tres Cantos, Spain., Lombardo E; Takeda Madrid, Cell Therapy Technology Center, Tres Cantos, Spain.

Publikováno v: Stem cell research & therapy [Stem Cell Res Ther] 2020 Nov 02; Vol. 11 (1), pp. 462. Date of Electronic Publication: 2020 Nov 02.

A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring.

Autor: Dowrey TW; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, Massachusetts, USA.; Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Cranston SF; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, Massachusetts, USA.; Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Skvir N; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, Massachusetts, USA.; Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Lok Y; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, Massachusetts, USA.; Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Gould B; Section of Geriatrics, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Petrowitz B; Section of Geriatrics, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Villar D; Albert Einstein College of Medicine, Bronx, New York, USA., Shan J; Albert Einstein College of Medicine, Bronx, New York, USA., James M; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, Massachusetts, USA., Dodge M; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, Massachusetts, USA., Belkina AC; Flow Cytometry Core Facility, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Giadone RM; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA., Milman S; Albert Einstein College of Medicine, Bronx, New York, USA., Sebastiani P; Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts, USA., Perls TT; Section of Geriatrics, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Andersen SL; Section of Geriatrics, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Murphy GJ; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, Massachusetts, USA.; Section of Hematology and Medical Oncology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.

Publikováno v: Aging cell [Aging Cell] 2024 Sep 25, pp. e14351. Date of Electronic Publication: 2024 Sep 25.

Exploiting urine-derived induced pluripotent stem cells for advancing precision medicine in cell therapy, disease modeling, and drug testing.

Autor: Yin, Xiya^1,2 (AUTHOR), Li, Qingfeng¹ (AUTHOR) dr.liqingfeng@shsmu.edu.cn, Shu, Yan³ (AUTHOR), Wang, Hongbing³ (AUTHOR), Thomas, Biju⁴ (AUTHOR), Maxwell, Joshua T.⁵ (AUTHOR), Zhang, Yuanyuan⁵ (AUTHOR) yzhang@wakehealth.edu

Publikováno v: Journal of Biomedical Science. 5/9/2024, Vol. 31 Issue 1, p1-20. 20p.

CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 ^N141I neurons.

Autor: Ortiz-Virumbrales M; Department of Neurology, NFL Neurological Care Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Moreno CL; Department of Neurology, NFL Neurological Care Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Kruglikov I; The New York Stem Cell Foundation Research Institute, New York, NY, USA., Marazuela P; Universidad Francisco de Vitoria, 28223 Pozuelo de Alarcón, Madrid, Spain., Sproul A; The New York Stem Cell Foundation Research Institute, New York, NY, USA.; Present Address: Taub Institute and the Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Jacob S; The New York Stem Cell Foundation Research Institute, New York, NY, USA., Zimmer M; The New York Stem Cell Foundation Research Institute, New York, NY, USA., Paull D; The New York Stem Cell Foundation Research Institute, New York, NY, USA., Zhang B; Department of Genetics and Genomic Sciences, Icahn Institute for Multi-Scale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Schadt EE; Department of Genetics and Genomic Sciences, Icahn Institute for Multi-Scale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Ehrlich ME; Department of Neurology, NFL Neurological Care Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Genetics and Genomic Sciences, Icahn Institute for Multi-Scale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Tanzi RE; Genetics and Aging Unit, Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA., Arancio O; Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA., Noggle S; The New York Stem Cell Foundation Research Institute, New York, NY, USA. snoggle@nyscf.org., Gandy S; Department of Neurology, NFL Neurological Care Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. samuel.gandy@mssm.edu.; Department of Psychiatry, Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. samuel.gandy@mssm.edu.

Publikováno v: Acta neuropathologica communications [Acta Neuropathol Commun] 2017 Oct 27; Vol. 5 (1), pp. 77. Date of Electronic Publication: 2017 Oct 27.