Pif1-Family helicases support fork convergence during DNA replication termination in eukaryotes

Autor: Deegan, Tom D, Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T P, Labib, Karim P M

Publikováno v: Deegan, T D, Baxter, J, Ortiz Bazán, M Á, Yeeles, J T P & Labib, K P M 2019, ' Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes ', Molecular Cell, vol. 74, no. 2, pp. 231-244.e9 . https://doi.org/10.1016/j.molcel.2019.01.040

The convergence of two DNA replication forks creates unique problems during DNA replication termination. In E. coli and SV40, the release of torsional strain by type II topoisomerases is critical for converging replisomes to complete DNA synthesis, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ef5388d35615a0536df600e0f73ec0de
http://sro.sussex.ac.uk/id/eprint/84526/1/Deegan_et_al_2019.pdf

Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage.

Autor: Saugar, Irene, Vázquez, María Victoria, Gallo-Fernández, María, Ortiz-Bazán, María Ángeles, Segurado, Mónica, Calzada, Arturo, Tercero, José Antonio

Publikováno v: Nucleic Acids Research; Oct2013, Vol. 41 Issue 19, p8943-8958, 16p

Rad5 plays a major role in the cellular response to DNA damage during chromosome replication.

Autor: Ortiz-Bazán MÁ; Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Cantoblanco, 28049 Madrid, Spain., Gallo-Fernández M; Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Cantoblanco, 28049 Madrid, Spain., Saugar I; Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Cantoblanco, 28049 Madrid, Spain., Jiménez-Martín A; Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Cantoblanco, 28049 Madrid, Spain., Vázquez MV; Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Cantoblanco, 28049 Madrid, Spain., Tercero JA; Centro de Biología Molecular Severo Ochoa (CSIC/UAM), Cantoblanco, 28049 Madrid, Spain. Electronic address: jatercero@cbm.csic.es.

Publikováno v: Cell reports [Cell Rep] 2014 Oct 23; Vol. 9 (2), pp. 460-8. Date of Electronic Publication: 2014 Oct 09.