Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ortal Shinikamin"'
Autor:
Shiri Shoob, Nadav Buchbinder, Ortal Shinikamin, Or Gold, Halit Baeloha, Tomer Langberg, Daniel Zarhin, Ilana Shapira, Gabriella Braun, Naomi Habib, Inna Slutsky
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The mechanisms that confer cognitive resilience to Alzheimer’s Disease (AD) are not fully understood. Here, we describe a neural circuit mechanism underlying this resilience in a familial AD mouse model. In the prodromal disease stage, int
Externí odkaz:
https://doaj.org/article/fc1606ff2f4243afa26d3548512e082e
Autor:
Daniel Zarhin, Refaela Atsmon, Antonella Ruggiero, Halit Baeloha, Shiri Shoob, Oded Scharf, Leore R. Heim, Nadav Buchbinder, Ortal Shinikamin, Ilana Shapira, Boaz Styr, Gabriella Braun, Michal Harel, Anton Sheinin, Nitzan Geva, Yaniv Sela, Takashi Saito, Takaomi Saido, Tamar Geiger, Yuval Nir, Yaniv Ziv, Inna Slutsky
Publikováno v:
Cell Reports
Summary Dysregulated homeostasis of neural activity has been hypothesized to drive Alzheimer’s disease (AD) pathogenesis. AD begins with a decades-long presymptomatic phase, but whether homeostatic mechanisms already begin failing during this silen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1061f838b73053272a122738f402f7
http://europepmc.org/articles/PMC8789564
http://europepmc.org/articles/PMC8789564