Deep phenotyping characterization of human unconventional CD8+NKG2A/C+ T cells among T and NK cells by spectral flow cytometry

Autor: Aurelio Orta-Resendiz, Caroline Petitdemange, Sandrine Schmutz, Béatrice Jacquelin, Sophie Novault, Nicolas Huot, Michaela Müller-Trutwin

Publikováno v: STAR Protocols, Vol 4, Iss 4, Pp 102734- (2023)

Summary: Here, we present a protocol for setting three spectral flow cytometry panels for the characterization of human unconventional CD8+NKG2A/C+ T cells as well as other T and natural killer cell subsets. We describe steps for standardizing, prepa

Externí odkaz: https://doaj.org/article/3cfcb1262030409ea6dc1e80520ee48e

COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms

Autor: Marek Ostaszewski, Anna Niarakis, Alexander Mazein, Inna Kuperstein, Robert Phair, Aurelio Orta‐Resendiz, Vidisha Singh, Sara Sadat Aghamiri, Marcio Luis Acencio, Enrico Glaab, Andreas Ruepp, Gisela Fobo, Corinna Montrone, Barbara Brauner, Goar Frishman, Luis Cristóbal Monraz Gómez, Julia Somers, Matti Hoch, Shailendra Kumar Gupta, Julia Scheel, Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber, Arnau Montagud, Miguel Ponce de Leon, Akira Funahashi, Yusuke Hiki, Noriko Hiroi, Takahiro G Yamada, Andreas Dräger, Alina Renz, Muhammad Naveez, Zsolt Bocskei, Francesco Messina, Daniela Börnigen, Liam Fergusson, Marta Conti, Marius Rameil, Vanessa Nakonecnij, Jakob Vanhoefer, Leonard Schmiester, Muying Wang, Emily E Ackerman, Jason E Shoemaker, Jeremy Zucker, Kristie Oxford, Jeremy Teuton, Ebru Kocakaya, Gökçe Yağmur Summak, Kristina Hanspers, Martina Kutmon, Susan Coort, Lars Eijssen, Friederike Ehrhart, Devasahayam Arokia Balaya Rex, Denise Slenter, Marvin Martens, Nhung Pham, Robin Haw, Bijay Jassal, Lisa Matthews, Marija Orlic‐Milacic, Andrea Senff-Ribeiro, Karen Rothfels, Veronica Shamovsky, Ralf Stephan, Cristoffer Sevilla, Thawfeek Varusai, Jean‐Marie Ravel, Rupsha Fraser, Vera Ortseifen, Silvia Marchesi, Piotr Gawron, Ewa Smula, Laurent Heirendt, Venkata Satagopam, Guanming Wu, Anders Riutta, Martin Golebiewski, Stuart Owen, Carole Goble, Xiaoming Hu, Rupert W Overall, Dieter Maier, Angela Bauch, Benjamin M Gyori, John A Bachman, Carlos Vega, Valentin Grouès, Miguel Vazquez, Pablo Porras, Luana Licata, Marta Iannuccelli, Francesca Sacco, Anastasia Nesterova, Anton Yuryev, Anita de Waard, Denes Turei, Augustin Luna, Ozgun Babur, Sylvain Soliman, Alberto Valdeolivas, Marina Esteban‐Medina, Maria Peña‐Chilet, Kinza Rian, Tomáš Helikar, Bhanwar Lal Puniya, Dezso Modos, Agatha Treveil, Marton Olbei, Bertrand De Meulder, Stephane Ballereau, Aurélien Dugourd, Aurélien Naldi, Vincent Noël, Laurence Calzone, Chris Sander, Emek Demir, Tamas Korcsmaros, Tom C Freeman, Franck Augé, Jacques S Beckmann, Jan Hasenauer, Olaf Wolkenhauer, Egon L Willighagen, Alexander R Pico, Chris T Evelo, Marc E Gillespie, Lincoln D Stein, Henning Hermjakob, Peter D'Eustachio, Julio Saez‐Rodriguez, Joaquin Dopazo, Alfonso Valencia, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID‐19 Disease Map Community

Publikováno v: Molecular Systems Biology, Vol 17, Iss 10, Pp 1-22 (2021)

Abstract We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and predicting key targets of intervention. Here, we describe

Externí odkaz: https://doaj.org/article/07d2352966634fc58ef9a394d1092d67

Persistent high levels of immune activation and correlations with HIV-1 proviral DNA and 2-LTR circle loads in a cohort of Mexican individuals following long-term and fully suppressive treatment

Autor: Aurelio Orta-Resendiz, Monica Viveros-Rogel, Luis L. Fuentes-Romero, Moises Vergara-Mendoza, Damaris P. Romero-Rodriguez, Monica Muñoz-Lopez, Martha L. Zancatl-Diaz, Elsa Y. Vidal-Laurencio, Roberto A. Rodriguez-Diaz, Luis E. Soto-Ramirez

Publikováno v: International Journal of Infectious Diseases, Vol 100, Iss , Pp 184-192 (2020)

Objectives: This study investigated the correlations between the human immunodeficiency virus type 1 (HIV-1) reservoir and immune activation levels in chronic patients under fully suppressive antiretroviral therapy (ART). Methods: We quantified the H

Externí odkaz: https://doaj.org/article/4309bd90302b42c3a4fd76be1fdf29da

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Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines

Autor: Rupsha Fraser, Aurelio Orta-Resendiz, Alexander Mazein, David H. Dockrell

Publikováno v: Fraser, R, Orta-Resendiz, A, Mazein, A & Dockrell, D H 2023, ' Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines ', Trends in Molecular Medicine, vol. 29, no. 4, pp. 255-267 . https://doi.org/10.1016/j.molmed.2023.01.003

SARS-CoV-2 vaccination significantly reduces morbidity and mortality, but has less impact on viral transmission rates, thus aiding viral evolution, and the longevity of vaccine-induced immunity rapidly declines. Immune responses in respiratory tract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c822a9a2905654a016c9a9de4bfe13a
https://doi.org/10.1016/j.molmed.2023.01.003