Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Orsolya Mózner"'
Autor:
Orsolya Mózner, Judit Moldvay, Kata Sára Szabó, Dorottya Vaskó, Júlia Domján, Dorottya Ács, Zoltán Ligeti, Csaba Fehér, Edit Hirsch, László Puskás, Cordula Stahl, Manfred Frey, Balázs Sarkadi
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3193 (2023)
We have developed a simple, rapid, high-throughput RBD-based ELISA to assess the humoral immunity against emerging SARS-CoV-2 virus variants. The cDNAs of the His-tagged RBD proteins of the virus variants were stably engineered into HEK cells secreti
Externí odkaz:
https://doaj.org/article/546b049f31c7434c94b9ec2bc1c8e371
Autor:
Orsolya Mózner, Boglárka Zámbó, Zsuzsa Bartos, Anna Gergely, Kata Sára Szabó, Bálint Jezsó, Ágnes Telbisz, György Várady, László Homolya, Tamás Hegedűs, Balázs Sarkadi
Publikováno v:
Membranes, Vol 13, Iss 10, p 822 (2023)
The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics, contributes to cancer drug resistance and the development of gout. In this work, we have analyzed the effects of selected variants, r
Externí odkaz:
https://doaj.org/article/d2e751a0cf98473c95d382c7980d6546
Autor:
Edit Szabó, Anna Kulin, Orsolya Mózner, László Korányi, Botond Literáti-Nagy, Márta Vitai, Judit Cserepes, Balázs Sarkadi, György Várady
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0260957 (2021)
Type 2 diabetes mellitus (T2DM) is a complex metabolic disease and variations in multispecific membrane transporter functions may affect T2DM development, complications or treatment. In this work we have analyzed the potential effects of a major poly
Externí odkaz:
https://doaj.org/article/d32775f11f4746248357adfa66a322ad
Autor:
Boglárka Zámbó, Zsuzsa Bartos, Orsolya Mózner, Edit Szabó, György Várady, Gyula Poór, Márton Pálinkás, Hajnalka Andrikovics, Tamás Hegedűs, László Homolya, Balázs Sarkadi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract The ABCG2 membrane protein is a key xeno- and endobiotic transporter, modulating the absorption and metabolism of pharmacological agents and causing multidrug resistance in cancer. ABCG2 is also involved in uric acid elimination and its impa
Externí odkaz:
https://doaj.org/article/985b89481f7e46d08466e8eaf2a472db
Publikováno v:
Membranes, Vol 11, Iss 8, p 586 (2021)
In the human ATP2B4 gene, coding for the plasma membrane calcium pump PMCA4b, a minor haplotype results in the decreased expression of this membrane protein in erythroid cells. The presence of this haplotype and the consequently reduced PMCA4b expres
Externí odkaz:
https://doaj.org/article/71b56dfe8841489d9341227f5509a075
Autor:
Ágnes Telbisz, Csilla Ambrus, Orsolya Mózner, Edit Szabó, György Várady, Éva Bakos, Balázs Sarkadi, Csilla Özvegy-Laczka
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 81 (2021)
During the COVID-19 pandemic, several repurposed drugs have been proposed to alleviate the major health effects of the disease. These drugs are often applied with analgesics or non-steroid anti-inflammatory compounds, and co-morbid patients may also
Externí odkaz:
https://doaj.org/article/c73bd9faab8d4e24a621c1d9885c5d7f
Autor:
Márton Pálinkás, Edit Szabó, Anna Kulin, Orsolya Mózner, Rita Rásonyi, Péter Juhász, Krisztina Nagy, György Várady, Dóra Vörös, Boglárka Zámbó, Balázs Sarkadi, Gyula Poór
Publikováno v:
Clinical and Experimental Medicine.
Gout is a common crystal induced disease of high personal and social burden, characterised by severe arthritis and comorbidity if untreated. Impaired function of ABCG2 transporter is causative in gout and may be responsible for renal-overload type hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cce3702a9ff7d489a46f7afb85cb243
https://doi.org/10.1007/s10238-022-00848-7
https://doi.org/10.1007/s10238-022-00848-7
Autor:
Henrietta Papp, Judit Bóvári-Biri, Krisztina Bánfai, Péter Juhász, Mohamed Mahdi, Lilian Cristina Russo, Dávid Bajusz, Adrienn Sipos, László Petri, Ágnes Kemény, Mónika Madai, Anett Kuczmog, Gyula Batta, Orsolya Mózner, Dorottya Vaskó, Edit Hirsch, Péter Bohus, Gábor Méhes, József Tőzsér, Nicola J. Curtin, Zsuzsanna Helyes, Attila Tóth, Nicolas C. Hoch, Ferenc Jakab, György M. Keserű, Judit E. Pongrácz, Péter Bai
Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2 virus, is a major global health challenge, as there is no efficient treatment for the moderate to severe disease. ADP-ribosylation events are involved in regulating the life cycle of coronavir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::145b8e760a029eba2091d7fe2df24c06
https://doi.org/10.1101/2022.06.30.22277079
https://doi.org/10.1101/2022.06.30.22277079
Publikováno v:
Cells, Vol 8, Iss 10, p 1215 (2019)
The human ABCG2 is an important plasma membrane multidrug transporter, involved in uric acid secretion, modulation of absorption of drugs, and in drug resistance of cancer cells. Variants of the ABCG2 transporter, affecting cellular processing and tr
Externí odkaz:
https://doaj.org/article/07f225ae8e1d422782d96cc8674cf559
Autor:
Zsuzsa Bartos, György Várady, György Török, László Homolya, Balázs Sarkadi, Orsolya Mózner, Boglárka Zámbó, Ágnes Telbisz, Tamás I. Orbán
Publikováno v:
Cellular and Molecular Life Sciences
The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics; thus the relatively frequent polymorphic and mutant ABCG2 variants in the population may significantly alter disease conditions and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f57502e119723c3b3a2da04085d0e46
https://doi.org/10.1007/s00018-019-03186-2
https://doi.org/10.1007/s00018-019-03186-2