Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Orsolya Gal"'
Autor:
Krisztina A. Szigeti, Alexandra Kalmár, Orsolya Galamb, Gábor Valcz, Barbara K. Barták, Zsófia B. Nagy, Sára Zsigrai, Ildikó Felletár, Árpád V. Patai, Tamás Micsik, Márton Papp, Eszter Márkus, Zsolt Tulassay, Peter Igaz, István Takács, Béla Molnár
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Hypomethylation of long interspersed nuclear element 1 (LINE-1) is characteristic of various cancer types, including colorectal cancer (CRC). Malfunction of several factors or alteration of methyl-donor molecules’ (folic acid an
Externí odkaz:
https://doaj.org/article/a3cba87d0ca445b29b049f95ed79730e
Autor:
Karin Kozbial, Monika Ferlitsch, Karoline Reinhart, Daniela Dunkler, Michael Trauner, Werner Weiss, Christina Bannert, Orsolya Gal, Michaela Hassler, Caspar Wiener, Sibylle Pramhas
Publikováno v:
JAMA. 306:1352
Although some studies have shown that men are at greater age-specific risk for advanced colorectal neoplasia than women, the age for referring patients to screening colonoscopy is independent of sex and usually recommended to be 50 years.To determine
Autor:
Alexandra Kalmár, Zsófia Brigitta Nagy, Orsolya Galamb, István Csabai, András Bodor, Barnabás Wichmann, Gábor Valcz, Barbara Kinga Barták, Zsolt Tulassay, Peter Igaz, Béla Molnár
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-16 (2019)
Abstract Background Long non-coding RNAs (lncRNAs) play a fundamental role in colorectal cancer (CRC) development, however, lncRNA expression profiles in CRC and its precancerous stages remain to be explored. We aimed to study whole genomic lncRNA ex
Externí odkaz:
https://doaj.org/article/9c98837527a349c5b7014a0a0fb4900c
Autor:
Sibylle Pramhas, Michaela Hassler, Karoline Reinhart, Werner Weiss, Monika Ferlitsch, Orsolya Gal, Caspar Wiener
Publikováno v:
Gastroenterology. 138:S-638
Autor:
Béla Molnár, Orsolya Galamb, Bálint Péterfia, Barnabás Wichmann, István Csabai, András Bodor, Alexandra Kalmár, Krisztina Andrea Szigeti, Barbara Kinga Barták, Zsófia Brigitta Nagy, Gábor Valcz, Árpád V. Patai, Péter Igaz, Zsolt Tulassay
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background DNA mutations occur randomly and sporadically in growth-related genes, mostly on cytosines. Demethylation of cytosines may lead to genetic instability through spontaneous deamination. Aims were whole genome methylation and targete
Externí odkaz:
https://doaj.org/article/232fcf15d244480b807e540b99e22783
Autor:
Barbara Kinga Barták, Alexandra Kalmár, Bálint Péterfia, Árpád V. Patai, Orsolya Galamb, Gábor Valcz, Sándor Spisák, Barnabás Wichmann, Zsófia Brigitta Nagy, Kinga Tóth, Zsolt Tulassay, Péter Igaz, Béla Molnár
Publikováno v:
Epigenetics, Vol 12, Iss 9, Pp 751-763 (2017)
Aberrant methylation is one of the most frequent epigenetic alterations that can contribute to tumor formation. Cell-free DNA can originate from tumor tissue; therefore, the evaluation of methylation markers in cell-free DNA can be a promising method
Externí odkaz:
https://doaj.org/article/08e2287f96fc4c1aa3f9998da55ad3fe
Autor:
Sára Zsigrai, Alexandra Kalmár, Zsófia B. Nagy, Barbara K. Barták, Gábor Valcz, Krisztina A. Szigeti, Orsolya Galamb, Titanilla Dankó, Anna Sebestyén, Gábor Barna, Vanessza Szabó, Orsolya Pipek, Anna Medgyes-Horváth, István Csabai, Zsolt Tulassay, Péter Igaz, István Takács, Béla Molnár
Publikováno v:
Cells, Vol 9, Iss 8, p 1864 (2020)
Global DNA hypomethylation is a characteristic feature of colorectal carcinoma (CRC). The tumor inhibitory effect of S-adenosylmethionine (SAM) methyl donor has been described in certain cancers including CRC. However, the molecular impact of SAM tre
Externí odkaz:
https://doaj.org/article/6ed380cf3d6b4ef4974e97eea8289f16
Autor:
Orsolya Galamb, Ferenc Sipos, Sándor Spisák, Barnabás Galamb, Tibor Krenács, Gábor Valcz, Zsolt Tulassay, Béla Molnár
Publikováno v:
Cellular Oncology, Vol 31, Iss 1, Pp 19-29 (2009)
Background: As most colorectal cancers (CRC) develop from villous adenomas, studying alterations in gene expression profiles across the colorectal adenoma–dysplasia–carcinoma sequence may yield potential biomarkers of disease progression.
Externí odkaz:
https://doaj.org/article/2eb1a7a00a1b4d33abe493a1416bd8a8
Autor:
Katalin Leiszter, Ferenc Sipos, Orsolya Galamb, Tibor Krenács, Gábor Veres, Barna Wichmann, István Fűri, Alexandra Kalmár, Árpád V Patai, Kinga Tóth, Gábor Valcz, Zsolt Tulassay, Béla Molnár
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118332 (2015)
BackgroundSomatostatin (SST) has anti-proliferative and pro-apoptotic effects. Our aims were to analyze and compare the SST expression during normal aging and colorectal carcinogenesis at mRNA and protein levels. Furthermore, we tested the methylatio
Externí odkaz:
https://doaj.org/article/a28cda0251054e1a880715224fc8df39
Autor:
Katalin Leiszter, Orsolya Galamb, Ferenc Sipos, Tibor Krenács, Gábor Veres, Barnabás Wichmann, Alexandra Kalmár, Árpád V Patai, Kinga Tóth, Gábor Valcz, Béla Molnár, Zsolt Tulassay
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e74140 (2013)
BACKGROUND AND AIMS: Sporadic colorectal cancer (CRC) development is a sequential process showing age-dependency, uncontrolled epithelial proliferation and decreased apoptosis. During juvenile growth cellular proliferation and apoptosis are well bala
Externí odkaz:
https://doaj.org/article/a4f83ce43296461894b85c99721351b6