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pro vyhledávání: '"Orsale MV"'
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Autor:
Nadia Gennari, Emanuela Nizi, Steven J. Harper, Savina Malancona, Sergio Altamura, Edith Monteagudo, David Roberts, Ilaria Biancofiore, Paul Willis, Maria Vittoria Orsale, Ottavia Cecchetti, Antonella Cellucci, Ralph Laufer, Rita Graziani, Alberto Bresciani, Simona Ponzi, Jesus Maria Ontoria Ontoria, Maria Veneziano, Annalise Di Marco, Giacomo Paonessa, Vincenzo Summa, Federica Ferrigno
Publikováno v:
ACS medicinal chemistry letters. 7(5)
The identification of a new series of P. falciparum growth inhibitors is described. Starting from a series of known human class I HDAC inhibitors a SAR exploration based on growth inhibitory activity in parasite and human cells-based assays led to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd9996399049eb56ee09a08a1c03acc
https://pubmed.ncbi.nlm.nih.gov/27190592
https://pubmed.ncbi.nlm.nih.gov/27190592
Autor:
Orsatti L; ADME/DMPK Department, IRBM SpA, Pomezia, Roma, Italy., Orsale MV; ADME/DMPK Department, IRBM SpA, Pomezia, Roma, Italy., di Pasquale P; ADME/DMPK Department, IRBM SpA, Pomezia, Roma, Italy., Vecchi A; ADME/DMPK Department, IRBM SpA, Pomezia, Roma, Italy., Colaceci F; ADME/DMPK Department, IRBM SpA, Pomezia, Roma, Italy., Ciammaichella A; Medicinal Chemistry Department, IRBM SpA, Pomezia, Roma, Italy., Rossetti I; Medicinal Chemistry Department, IRBM SpA, Pomezia, Roma, Italy., Bonelli F; ADME/DMPK Department, IRBM SpA, Pomezia, Roma, Italy., Baumgaertel K; Retrophin, San Diego, CA, United States of America., Liu K; Retrophin, San Diego, CA, United States of America., Elbaum D; Retrophin, San Diego, CA, United States of America., Monteagudo E; ADME/DMPK Department, IRBM SpA, Pomezia, Roma, Italy.
Publikováno v:
PloS one [PLoS One] 2021 May 21; Vol. 16 (5), pp. e0251981. Date of Electronic Publication: 2021 May 21 (Print Publication: 2021).
Autor:
Gallo M; IRBM Science Park S.p.A., Via Pontina km 30.600, 00071, Pomezia, Rome, Italy., Matteucci S; Dipartimento di Scienze e Tecnologie Chimiche, Università di Roma 'Tor Vergata', Via della Ricerca Scientifica, 00133, Rome, Italy., Alaimo N; Dipartimento di Scienze e Tecnologie Chimiche, Università di Roma 'Tor Vergata', Via della Ricerca Scientifica, 00133, Rome, Italy., Pitti E; Dipartimento di Scienze e Tecnologie Chimiche, Università di Roma 'Tor Vergata', Via della Ricerca Scientifica, 00133, Rome, Italy., Orsale MV; IRBM Science Park S.p.A., Via Pontina km 30.600, 00071, Pomezia, Rome, Italy., Summa V; IRBM Science Park S.p.A., Via Pontina km 30.600, 00071, Pomezia, Rome, Italy., Cicero DO; IRBM Science Park S.p.A., Via Pontina km 30.600, 00071, Pomezia, Rome, Italy; Dipartimento di Scienze e Tecnologie Chimiche, Università di Roma 'Tor Vergata', Via della Ricerca Scientifica, 00133, Rome, Italy. Electronic address: cicero@scienze.uniroma2.it., Monteagudo E; IRBM Science Park S.p.A., Via Pontina km 30.600, 00071, Pomezia, Rome, Italy. Electronic address: e.monteagudo@irbm.it.
Publikováno v:
Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2019 Apr 15; Vol. 167, pp. 21-29. Date of Electronic Publication: 2019 Jan 31.
Autor:
Ontoria JM; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Paonessa G; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Ponzi S; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Ferrigno F; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Nizi E; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Biancofiore I; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Malancona S; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Graziani R; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Roberts D; Medicines for Malaria Venture, ICC , Route de Pré-Bois 20, P.O. Box 1826, 1215 Geneva, Switzerland., Willis P; Medicines for Malaria Venture, ICC , Route de Pré-Bois 20, P.O. Box 1826, 1215 Geneva, Switzerland., Bresciani A; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Gennari N; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Cecchetti O; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Monteagudo E; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Orsale MV; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Veneziano M; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Di Marco A; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Cellucci A; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Laufer R; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Altamura S; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Summa V; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy., Harper S; Departments of Chemistry and Biology, IRBM Science Park , Via Pontina km 30,600, 00071 Pomezia, Rome, Italy.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2016 Mar 05; Vol. 7 (5), pp. 454-9. Date of Electronic Publication: 2016 Mar 05 (Print Publication: 2016).
Autor:
Orsatti L; IRBM Science Park, Via Pontina km 30,600, 00040 Pomezia (Roma), Italy. Electronic address: l.orsatti@irbm.it., Speziale R; IRBM Science Park, Via Pontina km 30,600, 00040 Pomezia (Roma), Italy. Electronic address: r.speziale@irbm.it., Orsale MV; IRBM Science Park, Via Pontina km 30,600, 00040 Pomezia (Roma), Italy. Electronic address: m.orsale@irbm.it., Caretti F; IRBM Science Park, Via Pontina km 30,600, 00040 Pomezia (Roma), Italy. Electronic address: f.caretti@irbm.it., Veneziano M; IRBM Science Park, Via Pontina km 30,600, 00040 Pomezia (Roma), Italy. Electronic address: m.veneziano@irbm.it., Zini M; IRBM Science Park, Via Pontina km 30,600, 00040 Pomezia (Roma), Italy. Electronic address: m.zini@irbm.it., Monteagudo E; IRBM Science Park, Via Pontina km 30,600, 00040 Pomezia (Roma), Italy. Electronic address: e.monteagudo@irbm.it., Lyons K; Freelance Consultant, P.O. Box 64, Holland, NY, USA. Electronic address: kathyalyons@gmail.com., Beconi M; Retrophin Inc. (RTRX), 301 Binney Street, 3rd Floor, Cambridge, MA 02142, USA. Electronic address: Maria.Beconi@retrophin.com., Chan K; Alcon Research, Ltd., 6201 South Freeway, Fort Worth, TX 76134-2099, USA. Electronic address: kelvinchan2014@verizon.net., Herbst T; CHDI Management/CHDI Foundation, 6080 Center Drive, Los Angeles, CA, USA. Electronic address: todd.herbst@chdifoundation.org., Toledo-Sherman L; CHDI Management/CHDI Foundation, 6080 Center Drive, Los Angeles, CA, USA. Electronic address: leticia.toledosherman@chdifoundation.org., Munoz-Sanjuan I; CHDI Management/CHDI Foundation, 6080 Center Drive, Los Angeles, CA, USA. Electronic address: ignacio.munoz@chdifoundation.org., Bonelli F; IRBM Science Park, Via Pontina km 30,600, 00040 Pomezia (Roma), Italy. Electronic address: f.bonelli@irbm.it., Dominguez C; CHDI Management/CHDI Foundation, 6080 Center Drive, Los Angeles, CA, USA. Electronic address: celia.dominguez@chdifoundation.org.
Publikováno v:
Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2015 Mar 25; Vol. 107, pp. 426-31. Date of Electronic Publication: 2015 Jan 24.
Autor:
Kinzel O; IRBM, Merck Research Laboratories Rome, Rome, Italy., Alfieri A, Altamura S, Brunetti M, Bufali S, Colaceci F, Ferrigno F, Filocamo G, Fonsi M, Gallinari P, Malancona S, Hernando JI, Monteagudo E, Orsale MV, Palumbi MC, Pucci V, Rowley M, Sasso R, Scarpelli R, Steinkühler C, Jones P
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2011 Aug 01; Vol. 21 (15), pp. 4429-35. Date of Electronic Publication: 2011 Jun 16.
Autor:
Monteagudo E; Department of DMPK, Istituto di Ricerche di Biologia Molecolare P. Angeletti, Merck Research Laboratories Rome, Via Pontina Km 30.600, Pomezia, Rome, Italy. e.monteagudo@irbm.it, Fonsi M, Chu X, Bleasby K, Evers R, Pucci V, Orsale MV, Cianetti S, Ferrara M, Harper S, Laufer R, Rowley M, Summa V
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2010 Dec; Vol. 40 (12), pp. 826-39. Date of Electronic Publication: 2010 Oct 07.
Autor:
Jones P; IRBM/Merck Research Labs Rome, Via Pontina km 30,600, 00040 Pomezia, Italy. philip_jones@merck.com, Altamura S, Boueres J, Ferrigno F, Fonsi M, Giomini C, Lamartina S, Monteagudo E, Ontoria JM, Orsale MV, Palumbi MC, Pesci S, Roscilli G, Scarpelli R, Schultz-Fademrecht C, Toniatti C, Rowley M
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2009 Nov 26; Vol. 52 (22), pp. 7170-85.
Autor:
Nizi E; Department of Medicinal Chemistry, IRBM-Merck Research Laboratories Rome, Pomezia, Italy. emanuela_nizi@merck.com, Orsale MV, Crescenzi B, Pescatore G, Muraglia E, Alfieri A, Gardelli C, Spieser SA, Summa V
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Aug 15; Vol. 19 (16), pp. 4617-21. Date of Electronic Publication: 2009 Jun 27.