Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Orru, Romano V.A."'
Autor:
de Souza, Igor O.P., Schrekker, Clarissa M.L., Lopes, William, Orru, Romano V.A., Hranjec, Marijana, Perin, Nataša, Machado, Michel, Oliveira, Luís F., Donato, Ricardo K., Stefani, Valter, Fuentefria, Alexandre M., Schrekker, Henri S.
Publikováno v:
In Journal of Photochemistry & Photobiology, B: Biology October 2016 163:319-326
Publikováno v:
Green Chemistry in Drug Discovery: From Academia to Industry, 237-267
STARTPAGE=237;ENDPAGE=267;TITLE=Green Chemistry in Drug Discovery
Methods in Pharmacology and Toxicology ISBN: 9781071615775
Cioc, R, Ruijter, E & Orru, R V A 2022, Multicomponent Synthesis : Cohesive Integration of Green Chemistry Principles . in P F Richardson (ed.), Green Chemistry in Drug Discovery : From Academia to Industry . Methods in Pharmacology and Toxicology, Humana Press Inc, pp. 237-267 . https://doi.org/10.1007/978-1-0716-1579-9_8
STARTPAGE=237;ENDPAGE=267;TITLE=Green Chemistry in Drug Discovery
Methods in Pharmacology and Toxicology ISBN: 9781071615775
Cioc, R, Ruijter, E & Orru, R V A 2022, Multicomponent Synthesis : Cohesive Integration of Green Chemistry Principles . in P F Richardson (ed.), Green Chemistry in Drug Discovery : From Academia to Industry . Methods in Pharmacology and Toxicology, Humana Press Inc, pp. 237-267 . https://doi.org/10.1007/978-1-0716-1579-9_8
The application of multicomponent reactions (MCRs) in the generation of compound libraries has long been recognized as a key strategy for the development of lead matter in drug discovery. Given the numerous advantages that these processes possess not
Autor:
Ruijter, Eelco, Orru, Romano V.A.
Publikováno v:
In Drug Discovery Today: Technologies Spring 2013 10(1):e15-e20
Autor:
Paravidino, Monica, Holt, Jarle, Romano, Diego, Singh, Neetu, Arends, Isabel W.C.E., Minnaard, Adriaan J., Orru, Romano V.A., Molinari, Francesco, Hanefeld, Ulf
Publikováno v:
In Journal of Molecular Catalysis. B, Enzymatic 2010 63(1):87-92
Publikováno v:
Targets in Heterocyclic Systems, 25, 256-280. Societa chimica italiana
van Schaik, T, Saya, J M, Ruijter, E & Orru, R V A 2021, ' BIOMIMETIC CASCADE STRATEGIES TOWARDS 2-AMINOINDOLINES FROM ALKALOIDS ', Targets in Heterocyclic Systems, vol. 25, pp. 256-280 . https://doi.org/10.17374/targets.2022.25.256
van Schaik, T, Saya, J M, Ruijter, E & Orru, R V A 2021, ' BIOMIMETIC CASCADE STRATEGIES TOWARDS 2-AMINOINDOLINES FROM ALKALOIDS ', Targets in Heterocyclic Systems, vol. 25, pp. 256-280 . https://doi.org/10.17374/targets.2022.25.256
The 2-aminoindoline scaffold is abundant in natural alkaloids with antibacterial, antitumor and anti-inflammatory activities. Synthetic organic chemists have developed various elegant strategies towards this heterocyclic core. These strategies often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9761df7b0febc2cbf87f00c11605aafe
https://research.vu.nl/en/publications/a86f5889-68a1-4212-9bef-58907e3e9644
https://research.vu.nl/en/publications/a86f5889-68a1-4212-9bef-58907e3e9644
Autor:
Escudero, Julien, Mampuys, Pieter, Mensch, Carl, Bheeter, Charles B., Vroemans, Robby, Orru, Romano V.A., Harvey, Jeremy, Maes, Bert U.W.
Publikováno v:
ACS Catalysis; 6/17/2022, Vol. 12 Issue 12, p6857-6873, 17p
Autor:
van Lint, Matthijs J., Hall, Mélanie, Faber, Kurt, van Spanning, Rob J.M., Ruijter, Eelco, Orru, Romano V.A.
Publikováno v:
European Journal of Organic Chemistry, 2019(5), 1092-1101. Wiley-VCH Verlag
van Lint, M J, Hall, M, Faber, K, van Spanning, R J M, Ruijter, E & Orru, R V A 2019, ' Stereoselective Chemoenzymatic Cascade Synthesis of the bis-THF Core of Acetogenins ', European Journal of Organic Chemistry, vol. 2019, no. 5, pp. 1092-1101 . https://doi.org/10.1002/ejoc.201801562
van Lint, M J, Hall, M, Faber, K, van Spanning, R J M, Ruijter, E & Orru, R V A 2019, ' Stereoselective Chemoenzymatic Cascade Synthesis of the bis-THF Core of Acetogenins ', European Journal of Organic Chemistry, vol. 2019, no. 5, pp. 1092-1101 . https://doi.org/10.1002/ejoc.201801562
bis-Tetrahydrofuran acetogenins are a class of natural products displaying highly potent and selective anti-tumor activity. Herein we report a new route to precursors of these natural products, utilizing the pseudo C2-symmetry in the central bis-tetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fcf999d10aa7fae1d9bb57ed4d0271ad
https://research.vu.nl/en/publications/6041346a-773a-4916-8426-7834495dd066
https://research.vu.nl/en/publications/6041346a-773a-4916-8426-7834495dd066
Publikováno v:
Microwaves in Organic Synthesis, Volume 1, Third Edition
Kruithof, A, Ruijter, E & Orru, R V A 2013, Microwave-Assisted Multicomponent Reactions in the Synthesis of Heterocycles . in A de la Hoz & A Loupy (eds), Microwaves in Organic Synthesis : Third Edition . vol. 2, Wiley-VCH, Weinheim, pp. 1099-1171 . https://doi.org/10.1002/9783527651313.ch24
Microwaves in Organic Synthesis: Third Edition, 2, 1099-1171
Kruithof, A, Ruijter, E & Orru, R V A 2013, Microwave-Assisted Multicomponent Reactions in the Synthesis of Heterocycles . in A de la Hoz & A Loupy (eds), Microwaves in Organic Synthesis : Third Edition . vol. 2, Wiley-VCH, Weinheim, pp. 1099-1171 . https://doi.org/10.1002/9783527651313.ch24
Microwaves in Organic Synthesis: Third Edition, 2, 1099-1171
Autor:
Dos Santos, Aurélie, Grimaud, Laurence, Ronsseray, Caroline, Coffinier, Didier, El Kaim, Laurent, Ruijter, Eelco, Orru, Romano V.A.
Publikováno v:
Coffinier, D, El Kaim, L, Grimaud, L, Ruijter, E & Orru, R V A 2011, ' A new multicomponent reaction for the synthesis of pyridines via cycloaddition of azadienes and ketenimines ', Tetrahedron Letters, vol. 52, no. 23, pp. 3023-3025 . https://doi.org/10.1016/j.tetlet.2011.04.007
Tetrahedron Letters
Tetrahedron Letters, Elsevier, 2011, 52 (23), pp.3023-3025. ⟨10.1016/j.tetlet.2011.04.007⟩
Tetrahedron Letters, 52(23), 3023-3025. Elsevier Limited
Tetrahedron Letters
Tetrahedron Letters, Elsevier, 2011, 52 (23), pp.3023-3025. ⟨10.1016/j.tetlet.2011.04.007⟩
Tetrahedron Letters, 52(23), 3023-3025. Elsevier Limited
The ketenimines resulting from a Nef isocyanide/Perkow sequence react with 1-azadienes to form pyridines or pyrimidines depending on their substitution pattern. The reaction is most efficient with ester-substituted ketenimines which leads to pyridine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c28a6a8046248ad8505085acffc06ee
https://research.vu.nl/en/publications/c97045e3-7026-444d-b4ff-84c8d326d570
https://research.vu.nl/en/publications/c97045e3-7026-444d-b4ff-84c8d326d570