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Impact of BCR::ABL1single nucleotide variants on asciminib efficacy

Autor: Innes, Andrew J., Hayden, Chloe, Orovboni, Victoria, Claudiani, Simone, Fernando, Fiona, Khan, Afzal, Rees, David, Byrne, Jennifer, Gallipoli, Paolo, Francis, Sebastian, Copland, Mhairi, Horne, Gillian, Raghavan, Manoj, Arnold, Claire, Collins, Angela, Cranfield, Tanya, Cunningham, Nicholas, Danga, Akila, Forsyth, Peter, Frewin, Rebecca, Garland, Paula, Hannah, Guy, Avenoso, Daniele, Hassan, Sandra, Huntly, Brian J. P., Husain, Jissan, Makkuni, Sudhakaran, Rothwell, Kate, Khorashad, Jamshid, Apperley, Jane F., Milojkovic, Dragana

Publikováno v: Leukemia; November 2024, Vol. 38 Issue: 11 p2443-2455, 13p

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Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy.

Autor: Innes AJ; Centre for Haematology, Faculty of Medicine, Imperial College London, London, United Kingdom. a.innes@imperial.ac.uk.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom. a.innes@imperial.ac.uk., Hayden C; North West London Pathology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom., Orovboni V; North West London Pathology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom., Claudiani S; Centre for Haematology, Faculty of Medicine, Imperial College London, London, United Kingdom.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom., Fernando F; Centre for Haematology, Faculty of Medicine, Imperial College London, London, United Kingdom.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom., Khan A; Centre for Haematology, Faculty of Medicine, Imperial College London, London, United Kingdom.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom., Rees D; Medical School, Faculty of Medicine, Imperial College London, London, United Kingdom., Byrne J; Centre for Clinical Haematology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom., Gallipoli P; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Francis S; Department of haematology, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom., Copland M; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Horne G; Paul O'Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Raghavan M; Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, United Kingdom., Arnold C; Department of Haematology, Belfast City Hospital, Belfast, United Kingdom., Collins A; Department of Haematology, Norfolk and Norwich University Hospital, Norwich, United Kingdom., Cranfield T; Department of Haematology, Queen Alexandra Hospital, Portsmouth, United Kingdom., Cunningham N; Department of Haematology, Belfast City Hospital, Belfast, United Kingdom., Danga A; Department of Haematology, The Hillingdon Hospital, London, United Kingdom., Forsyth P; Department of Haematology, Raigmore Hospital, NHS Highland, Inverness, United Kingdom., Frewin R; Department of Haematology, Gloucestershire Royal Hospital, Gloucester, United Kingdom., Garland P; Department of Haematology, Princess Royal University Hospital, London, United Kingdom., Hannah G; Department of Haematology, Kings College Hospital, London, United Kingdom., Avenoso D; Department of Haematology, Kings College Hospital, London, United Kingdom., Hassan S; Department of Haematology, Queen's Hospital, Romford, United Kingdom., Huntly BJP; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom., Husain J; Department of Haematology, Ashford and St Peter's Hospitals NHS Foundation Trust, Chertsey, United Kingdom., Makkuni S; Department of Haematology, Mid and South Essex NHS Foundation Trust, Basildon, United Kingdom., Rothwell K; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Basildon, United Kingdom., Khorashad J; Centre for Haematology, Faculty of Medicine, Imperial College London, London, United Kingdom.; Haemato-oncology Molecular Diagnostic Unit, The Royal Marsden Hospital NHS Foundation Trust, Sutton, United Kingdom., Apperley JF; Centre for Haematology, Faculty of Medicine, Imperial College London, London, United Kingdom.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom., Milojkovic D; Centre for Haematology, Faculty of Medicine, Imperial College London, London, United Kingdom.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.

Publikováno v: Leukemia [Leukemia] 2024 Nov; Vol. 38 (11), pp. 2443-2455. Date of Electronic Publication: 2024 Sep 17.