Zobrazeno 1 - 10
of 474
pro vyhledávání: '"Ornithine Decarboxylase Inhibitor"'
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Background Inhibitors of ornithine decarboxylase (ODC) are effective at preventing colorectal cancer (CRC). However, their high toxicity limits their clinical application. This study was aimed to explore the potential of microRNAs (miRNAs) a
Externí odkaz:
https://doaj.org/article/5c8b265355894efcaa3789fd9d0296d0
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1978 Oct 01. 75(10), 4699-4703.
Externí odkaz:
https://www.jstor.org/stable/68983
Publikováno v:
J Nat Prod
The natural product allicin is a reactive sulfur species (RSS) from garlic (Allium sativum L.). Neuroblastoma (NB) is an early childhood cancer arising from the developing peripheral nervous system. Ornithine decarboxylase (ODC) is a rate-limiting en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4cb0f1e836c5db566b16d500add513
https://pubmed.ncbi.nlm.nih.gov/32786875
https://pubmed.ncbi.nlm.nih.gov/32786875
Publikováno v:
Experimental Parasitology. 192:1-5
Two tetradentated pyridine-based manganese complexes (Cpd2 and Cpd3) were previously reported to inhibit efficiently the growth of Trypanosoma cruzi in vitro and in vivo. Cpd3 was also shown to be a potent inhibitor of trypanosomal iron superoxide di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59dd6a064bffbd9d5c5deb95cf99939
https://doi.org/10.1016/j.exppara.2018.07.005
https://doi.org/10.1016/j.exppara.2018.07.005
Autor:
Matthew Dunworth, Tracy Murray-Stewart, Michael J. Gambello, Brandi Wasek, Robert A. Casero, James T. McKenna, David Kapfhamer, Jason M. Kinchen, Teodoro Bottiglieri
Publikováno v:
Human Molecular Genetics. 27:2113-2124
Tuberous sclerosis complex (TSC) is an autosomal dominant neurodevelopmental disorder and the quintessential disorder of mechanistic Target of Rapamycin Complex 1 (mTORC1) dysregulation. Loss of either causative gene, TSC1 or TSC2, leads to constitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c12a1bc2aae2a874ee696c81a5939f
https://doi.org/10.1093/hmg/ddy118
https://doi.org/10.1093/hmg/ddy118
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Maisa S. Fonseca, Bethânia V. Resende, Douglas de Souza Moreira, Ana Maria Murta Santi, Silvane M. F. Murta, Antônio P. Zoboli, Marcelo A. Comini
Publikováno v:
Experimental Parasitology. 175:36-43
Trypanosomatids present a unique mechanism for detoxification of peroxides that is dependent on trypanothione (bisglutathionylspermidine). Ornithine decarboxylase (ODC) and γ-glutamylcysteine synthetase (GSH1) produce molecules that are direct precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271c488a789a39fd9d56f7c024b9c6ed
https://doi.org/10.1016/j.exppara.2017.02.001
https://doi.org/10.1016/j.exppara.2017.02.001
Autor:
K. Yu. Permyakova, O. V. Masalova, E. I. Samokhvalov, Alla A. Kushch, E. I. Lesnova, Sergey N. Kochetkov, Alexander V. Ivanov
Publikováno v:
Молекулярная биология. :512-523
Hepatitis C virus (HCV) induces the expression of the genes of proinflammatory cytokines, the excessive production of which may cause cell death, and contribute to development of liver fibrosis and hepatocarcinoma. The relationship between cytokine p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::904af7ebcf94d76ef5025fb85b4a4820
https://doi.org/10.7868/s0026898417030120
https://doi.org/10.7868/s0026898417030120
Autor:
Kamal El Bissati, Henry Redel, Li-Min Ting, Joseph D. Lykins, Martin J. McPhillie, Rajendra Upadhya, Patrick M. Woster, Nigel Yarlett, Kami Kim, Louis M. Weiss
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Twenty-two compounds belonging to several classes of polyamine analogs have been examined for their ability to inhibit the growth of the human malaria parasite Plasmodium falciparum in vitro and in vivo. Four lead compounds from the thiourea sub-seri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad42a4e2421c1336ffff93cefb58c972