Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ornella Tinti"'
Autor:
Nazareno Scafetta, Giancarlo Gramiccioli, Fabrizio Giorgi, Francesco De Angelis, Menotti Calvani, and Maria Ornella Tinti, Grazia Gallo, Mose Santaniello, Luciana Critelli
Publikováno v:
Journal of Medicinal Chemistry. 41:2227-2233
A new class of antimicrobial, "soft", quaternary ammonium l-carnitine esters, of the type (CH3)3N+-CH2-CHOCO(R1)-CH2-COO(R2) Cl-, has been designed, with R1 and R2 being in general long-chain alkyl substituents. The series shows good activity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22023fffe1cecfb655d5a3eaac52be0
https://doi.org/10.1021/jm970305x
https://doi.org/10.1021/jm970305x
Autor:
Francesco Gasparrini, Fabio Giannessi, Maria Ornella Tinti, Alessandra Di Tullio, Ilaria D'Acquarica, Paola Desiderio, Claudio Villani, S. Muck, Fabrizio Piccirilli
Publikováno v:
ChemInform. 33
The enantiomers of carnitine are converted on-line in the injection port of a gas chromatograph into β-hydroxy-γ-butyrolactones and are separated on a derivatized β-cyclodextrin chiral stationary phase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4ae8202fe34a0b0c767d9e623fbe66d
https://doi.org/10.1002/chin.200225184
https://doi.org/10.1002/chin.200225184
Autor:
Andrea Ciacci, Giuseppe Giannini, Marcella Marcellini, Mauro Marzi, Paolo Carminati, Claudio Pisano, Teresa Riccioni, M. Ornella Tinti, Isabella Lustrati, Domenico Alloatti, Mario B. Guglielmi, Walter Cabri, Grazia Gallo
With the aim of understanding the influence of fluorine on the double bond of the cis-stilbene moiety of combretastatin derivatives and encouraged by a preliminary molecular modeling study showing a different biological environment on the interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806e4aac8c8d6830a336439370aee686
http://hdl.handle.net/11585/756794
http://hdl.handle.net/11585/756794
Autor:
Isabella Fiorini, Paolo Carminati, Patrizia Minetti, Alfredo Cagnotto, Tiziana Mennini, M. Antonietta Stasi, Orlando Ghirardi, Ilario Mereghetti, M. Assunta Di Cesare, Bruno Catalanotti, Ornella Tinti, Stefano Di Serio, Vito Nacci, Stefania Butini, Caterina Fattorusso, Sandra Gemma, Francesco Trotta, Giuseppe Campiani
Using rational drug design to develop atypical antipsychotic drug candidates, we generated novel and metabolically stable pyrrolobenzazepines with an optimized pK(i) 5-HT(2A)/D(2) ratio. 5a, obtained by a new palladium-catalyzed three-step synthesis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4425c53833c6b14a20fdfb95b56b503
http://hdl.handle.net/11588/200943
http://hdl.handle.net/11588/200943
Autor:
Orlando Ghirardi, Ilario Mereghetti, Massimo Castorina, Patrizia Minetti, M. Antonietta Stasi, Elena Morelli, Ornella Tinti, Vito Nacci, Stefano Di Serio, Alfredo Cagnotto, Miriana Carli, Licia Pacifici, Nazzareno Scafetta, Giuseppe Campiani, Stefania Butini, Caterina Fattorusso, Sandra Gemma, Tiziana Mennini, M. Assunta Di Cesare, Bruno Galletti, Domenico Mastroianni, Paolo Carminati, Mario Vertechy, Bruno Catalanotti
Publikováno v:
ResearcherID
Recently we reported the pharmacological characterization of the 9,10-dihydropyrrolo[1,3]benzothiazepine derivative (S)-(+)-8 as a novel atypical antipsychotic agent. This compound had an optimum pK(i) 5-HT(2A)/D(2) ratio of 1.21 (pK(i) 5-HT(2A) = 8.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cd238cf464644cefa3306780bf2fd3
http://hdl.handle.net/11588/200968
http://hdl.handle.net/11588/200968
Autor:
Claudio Pisano, Loredana Vesci, Enrico Garattini, Yesim Kalac, Peter Kollar, Paolo Carminati, Giampiero Moretti, Alessandra Rinaldi, Fabiana Fosca Ferrara, Mineko Terao, Ornella Tinti, Vincenzo Giordano, Alessandro Rambaldi, Richard Tancredi, Antonio Devoto, Maurizio Gianni, Sergio Penco, Mauro Marzi
Publikováno v:
Blood. 100(10)
Enhancing the pharmacologic activity of all-transretinoic acid (ATRA) is potentially useful in the management of acute promyelocytic leukemia (APL) and other types of myeloid leukemia. In this report, we identify a novel class of experimental agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b04b60e7ecfeef6b31acaecf32dba74
https://pubmed.ncbi.nlm.nih.gov/12393712
https://pubmed.ncbi.nlm.nih.gov/12393712
Autor:
S. Muck, Francesco Gasparrini, Fabio Giannessi, Ilaria D'Acquarica, Paola Desiderio, Fabrizio Piccirilli, Claudio Villani, Maria Ornella Tinti, Alessandra Di Tullio
Publikováno v:
Scopus-Elsevier
The enantiomers of carnitine are converted on-line in the injection port of a gas chromatograph into beta-hydroxy-gamma-butyrolactones and are separated on a derivatized beta-cyclodextrin chiral stationary phase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc0a5f044816ea3c77df1cb7357be9b
https://pubmed.ncbi.nlm.nih.gov/12120548
https://pubmed.ncbi.nlm.nih.gov/12120548
Autor:
Vito Nacci, Bruno Catalanotti, Orlando Ghirardi, M. Antonietta Stasi, Nazzareno Scafetta, Domenico Mastroianni, Patrizia Minetti, Gianluca Giorgi, Alfredo Cagnotto, Paolo Carminati, Bruno Galletti, Ornella Tinti, Licia Pacifici, Tiziana Mennini, Mara Goegan, M. Assunta Di Cesare, Massimo Castorina, Giuseppe Campiani, Stefania Butini, Caterina Fattorusso, Sandra Gemma
The prototypical dopamine and serotonin antagonist (+/-)-7-chloro-9-(4-methylpiperazin-1-yl)-9,10-dihydropyrrolo[2,1-b][1,3]benzothiazepine (5) was resolved into its R and S enantiomers via crystallization of the diastereomeric tartaric acid salts. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7242cc026a21da1ffb1bf9100ab8aa3
http://hdl.handle.net/11365/19281
http://hdl.handle.net/11365/19281
Autor:
Vito Nacci, Patrizia Minetti, Sandra Gemma, Stefania Butini, Giuseppe Campiani, Ornella Tinti, Elena Morelli
Publikováno v:
ResearcherID
The synthesis of ethyl (2-acetyl-1-cyano-1,2,3,4-tetrahydro-1-isoquinolyl)acetate was accomplished by cyanation/acylation of the dihydroquinoline ring system. The selective cobalt boride catalyzed reduction of the cyano group of the cyanoester interm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1298ce02335bfe3d52e965ee967070ca
http://hdl.handle.net/11365/3275
http://hdl.handle.net/11365/3275
Autor:
Francesco De Angelis, Giampiero Moretti, and Maria Ornella Tinti, Patrizia Minetti, Mauro Marzi
Publikováno v:
The Journal of organic chemistry. 65(20)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8001d39baf898b69a0b8bcd74d74f7
https://pubmed.ncbi.nlm.nih.gov/11052133
https://pubmed.ncbi.nlm.nih.gov/11052133