Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Orna Man"'
Publikováno v:
PLoS ONE, Vol 2, Iss 8, p e682 (2007)
Olfactory receptors (ORs) are the largest gene family in mammalian genomes. Since nearly all OR genes are orphan receptors, inference of functional similarity or differences between odorant receptors typically relies on sequence comparisons. Based on
Externí odkaz:
https://doaj.org/article/5523a8d86dac4c318dced8e5d3e8e015
Autor:
Ran Blekhman, Carolin Kosiol, Orna Man, Carlos Bustamante, Adam R. Boyko, Amit Indap, Molly Przeworski, Kosuke M. Teshima, Leslie Herrmann
Publikováno v:
Current Biology. 18:883-889
SummaryWhat evolutionary forces shape genes that contribute to the risk of human disease? Do similar selective pressures act on alleles that underlie simple versus complex disorders [1–3]? Answers to these questions will shed light onto the origin
Autor:
Yitzhak Pilpel, Orna Man
Publikováno v:
Nature Genetics. 39:415-421
A major challenge in comparative genomics is to understand how phenotypic differences between species are encoded in their genomes. Phenotypic divergence may result from differential transcription of orthologous genes, yet less is known about the inv
Publikováno v:
Protein Science. 13:240-254
Olfactory receptors (ORs) are a large family of proteins involved in the recognition and discrimination of numerous odorants. These receptors belong to the G-protein coupled receptor (GPCR) hyperfamily, for which little structural data are available.
Publikováno v:
Proceedings of the National Academy of Sciences. 100:3324-3327
Olfactory receptor (OR) genes constitute the basis for the sense of smell and are encoded by the largest mammalian gene superfamily of >1,000 genes. In humans, >60% of these are pseudogenes. In contrast, the mouse OR repertoire, although of roughly e
Publikováno v:
Human Molecular Genetics. 11:1381-1390
We investigated the population differences in patterns of single nucleotide polymorphisms (SNPs) for a 400 kb olfactory receptor (OR) gene cluster on human chromosome 17p13.3. Samples were drawn from 35 individuals, of four different ethnogeographica
Autor:
Boleslaw Goldman, Michael Eldar, Edna Ben-Asher, Orna Man, Doron Lancet, Nili Avidan, Avraham Lorber, Asad Khoury, Elon Pras, Hadas Lahat, Etgar Levy-Nissenbaum, Tsviya Olender
Publikováno v:
The American Journal of Human Genetics. 69(6):1378-1384
Catecholamine-induced polymorphic ventricular tachycardia (PVT) is characterized by episodes of syncope, seizures, or sudden death, in response to physical activity or emotional stress. Two modes of inheritance have been described: autosomal dominant
Publikováno v:
Systems Biology and Regulatory Genomics ISBN: 9783540482932
Systems Biology and Regulatory Genomics
Scopus-Elsevier
Systems Biology and Regulatory Genomics
Scopus-Elsevier
Phenotypic differences between closely-related species may arise from differential expression regimes, rather than different gene complements. Knowledge of cellular protein levels across a species sample would thus be useful for the inference of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ee3c27f64624d260a9a4fa6ea0741c
https://doi.org/10.1007/978-3-540-48540-7_10
https://doi.org/10.1007/978-3-540-48540-7_10
Autor:
Clifford E. Felder, Jaime Prilusky, Orna Man, Tzviya Zeev-Ben-Mordehai, Jacques S. Beckmann, Joel L. Sussman, Edwin H. Rydberg, Israel Silman
Publikováno v:
Bioinformatics, vol. 21, no. 16, pp. 3435-8
Bioinformatics, 21(16), 3435. Oxford University Press
Bioinformatics, 21(16), 3435. Oxford University Press
Summary: An easy-to-use, versatile and freely available graphic web server, FoldIndex© is described: it predicts if a given protein sequence is intrinsically unfolded implementing the algorithm of Uversky and co-workers, which is based on the averag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4090e8efd50389bf43e3f6f2622c167
https://serval.unil.ch/resource/serval:BIB_072223A553B5.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_072223A553B5.P001/REF.pdf
Autor:
Xose S. Puente, Edward J. Kulbokasl, Tina Graves, Lucinda L. Fulton, Xiaoqiu Huang, Wolfgang Enard, Tracie L. Miner, Peer Bork, Arian F.A. Smit, Mario Ventura, Ge Liu, Eray Tüzün, Jean L. Chang, W. James Kent, Daniel J. Richter, Robert H. Waterston, Maryellen Ruvolo, Sante Gnerre, Toshiyuki Hayakawa, David B. Jaffe, Ines Hellmann, Svante Pääbo, Ajit Varki, Gloria Velasco, Carlos López-Otín, Asif T. Chinwalla, Orna Man, Gustavo Glusman, Catrina Fronick, Katherine S. Pollard, Tarjei S. Mikkelsen, Craig Pohl, Nick Patterson, Scott M. Smith, Kateryna D. Makova, Jonathan Butler, William E. Nash, Mariano Rocchi, Pieter J. de Jong, Ze Cheng, Evan E. Eichler, Hongkai Ji, Mikita Suyama, Tasha K. Altheide, Kerstin Lindblad-Toh, Yoav Gilad, Kay Prüfer, James E. Taylor, Karen E. Hayden, Joanne O. Nelson, Mary Claire King, Evan Mauceli, Michael C. Wendl, Ming K. Lee, David Reich, Richard K. Wilson, Eric S. Lander, Nicoletta Archidiacono, Kimberley D. Delehaunty, Shiaw-Pyng Yang, Kate R. Rosenbloom, LaDeana W. Hillier, Michael C. Zody, John W. Wallis, David Torrents, Stephen F. Schaffner, Elaine R. Mardis
Publikováno v:
Nature. 437(7055)
Here we present a draft genome sequence of the common chimpanzee (Pan troglodytes). Through comparison with the human genome, we have generated a largely complete catalogue of the genetic differences that have accumulated since the human and chimpanz