Periplakin Interferes with G Protein Activation by the Melanin-concentrating Hormone Receptor-1 by Binding to the Proximal Segment of the Receptor C-terminal Tail

Autor: Murdoch, Hannah ^‡, Feng, Gui-Jie ^‡, Bächner, Dietmar ^§, Ormiston, Laura ^‡, White, Julia H. ^¶, Richter, Dietmar ^§, Milligan, Graeme ^{‡, ∥}

Publikováno v: In Journal of Biological Chemistry 4 March 2005 280(9):8208-8220

The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation.

Autor: Milasta S; Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, UK., Evans NA, Ormiston L, Wilson S, Lefkowitz RJ, Milligan G

Publikováno v: The Biochemical journal [Biochem J] 2005 May 01; Vol. 387 (Pt 3), pp. 573-84.