Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Ormandy CJ"'
Autor:
Piggin CL, Roden DL, Law AMK, Molloy MP, Krisp C, Swarbrick A, Naylor MJ, Kalyuga M, Kaplan W, Oakes SR, Gallego-Ortega D, Clark SJ, Carroll JS, Bartonicek N, Ormandy CJ
Acquired resistance to endocrine therapy is responsible for half of the therapeutic failures in the treatment of breast cancer. Recent findings have implicated increased expression of the ETS transcription factor ELF5 as a potential modulator of estr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::ef7b9c365267aa533a870a9ad19e6c61
https://hdl.handle.net/10453/144195
https://hdl.handle.net/10453/144195
Autor:
Castillo L, Young AIJ, Mawson A, Schafranek P, Steinmann AM, Nessem D, Parkin A, Johns A, Chou A, Law AMK, Lucas MC, Murphy KJ, Deng N, Gallego-Ortega D, Caldon CE, Australian Pancreatic Cancer Genome Initiative (APGI), Timpson P, Pajic M, Ormandy CJ, Oakes SR
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest malignancies. It is phenotypically heterogeneous with a highly unstable genome and provides few common therapeutic targets. We found that MCL1, Cofilin1 (CFL1) and SRC mRNA were hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::6c1e7aebf93256bc3fd0ad16986ca325
https://hdl.handle.net/10453/144833
https://hdl.handle.net/10453/144833
Autor:
Hassanzadeh-Barforoushi, A, Law, AMK, Hejri, A, Asadnia, M, Ormandy, CJ, Gallego-Ortega, D, Ebrahimi Warkiani, M
© 2018 The Royal Society of Chemistry. We present here a new method to easily and reliably generate an array of hundreds of dispersed nanoliter-volume semi-droplets for single-cells culture and analysis. The liquid segmentation step occurs directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::9101c71eaf084ac58b3e865ed0d65594
https://hdl.handle.net/10453/132023
https://hdl.handle.net/10453/132023
Autor:
Law, AMK, Yin, JXM, Castillo, L, Young, AIJ, Piggin, C, Rogers, S, Caldon, CE, Burgess, A, Millar, EKA, O'Toole, SA, Gallego-Ortega, D, Ormandy, CJ, Oakes, SR
Quantification of cellular antigens and their interactions via antibody-based detection methods are widely used in scientific research. Accurate high-throughput quantitation of these assays using general image analysis software can be time consuming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::185e9d7a6ec496429a842f53776822a3
https://hdl.handle.net/10453/156216
https://hdl.handle.net/10453/156216
Autor:
Vennin, C, Chin, VT, Warren, SC, Lucas, MC, Herrmann, D, Magenau, A, Melenec, P, Walters, SN, Del Monte-Nieto, G, Conway, JRW, Nobis, M, Allam, AH, McCloy, RA, Currey, N, Pinese, M, Boulghourjian, A, Zaratzian, A, Adam, AAS, Heu, C, Nagrial, AM, Chou, A, Steinmann, A, Drury, A, Froio, D, Giry-Laterriere, M, Harris, NLE, Phan, T, Jain, R, Weninger, W, McGhee, EJ, Whan, R, Johns, AL, Samra, JS, Chantrill, L, Gill, AJ, Kohonen-Corish, M, Harvey, RP, Biankin, AV, Australian Pancreatic Cancer Genome Initiative (APGI), Evans, TRJ, Anderson, KI, Grey, ST, Ormandy, CJ, Gallego-Ortega, D, Wang, Y, Samuel, MS, Sansom, OJ, Burgess, A, Cox, TR, Morton, JP, Pajic, M, Timpson, P
The emerging standard of care for patients with inoperable pancreatic cancer is a combination of cytotoxic drugs gemcitabine and Abraxane, but patient response remains moderate. Pancreatic cancer development and metastasis occur in complex settings,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::0d5a9b78d701c3ded4723929d771cffb
https://hdl.handle.net/10453/156230
https://hdl.handle.net/10453/156230
SUMMARY The ETS transcription factor ELF5 specifies the formation of the secretory cell lineage of the mammary gland during pregnancy, by directing cell fate decisions of the mammary progenitor cells. The decision-making activity continues in breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::5d351a66a137f722f181d6328e560bfe
https://hdl.handle.net/10453/166469
https://hdl.handle.net/10453/166469
Autor:
Ortiz-Padilla, C, Gallego-Ortega, D, Browne, BC, Hochgräfe, F, Caldon, CE, Lyons, RJ, Croucher, DR, Rickwood, D, Ormandy, CJ, Brummer, T, Daly, RJ
Grb2-associated binder 1 (Gab1) is a docking protein that transduces signals from a variety of tyrosine kinases, including Met and the epidermal growth factor receptor (EGFR). Although the related protein Gab2 is strongly implicated in human cancer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::2a8e1e3b7388f606970d2a2f6e2bedf5
https://hdl.handle.net/10453/166471
https://hdl.handle.net/10453/166471
Autor:
Lee, HJ, Hinshelwood, RA, Bouras, T, Gallego-Ortega, D, Valdés-Mora, F, Blazek, K, Visvader, JE, Clark, SJ, Ormandy, CJ
Recent characterization of mammary stem and progenitor cells has improved our understanding of the transcriptional network that coordinates mammary development; however, little is known about the mechanisms that enforce lineage commitment and prevent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::85e004623847243a2c0a363d934ecfcf
https://hdl.handle.net/10453/166473
https://hdl.handle.net/10453/166473
Hypothalamic neuropeptide Y (NPY) has been implicated in the regulation of energy balance and reproduction, and chronically elevated NPY levels in the hypothalamus are associated with obesity and reduced reproductive function. However, it is not know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______293::7de42f577485ac6a24c48939999fa398
https://hdl.handle.net/2123/16068
https://hdl.handle.net/2123/16068
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