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Autor:
Prajakta Kalkar, Zohar Zvi Zamir, Sagie Schif-Zuck, Sarit Larisch, Amiram Ariel, Orly Zeytuni-Timor, Naama Maimon
Publikováno v:
Apoptosis. 25:558-573
ARTS (Sept4_i2) is a pro-apoptotic protein and a product of the Sept4 gene. ARTS acts upstream of mitochondria to initiate caspase activation. ARTS induces apoptosis by specifically binding XIAP and allowing de-repression of active caspases required