Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Orly Weizer-Stern"'
Autor:
Osnat Ashur-Fabian, Ofer Margalit, Orly Weizer-Stern, Adi Har-Zahav, A. Shaish, Gideon Rechavi, Dror Harats, Dan Dominissini, Hila Wiener Amram, Ninette Amariglio
Publikováno v:
Cell Cycle. 9:3785-3794
p53 is an established tumor suppressor gene activating the transcription of multiple target genes. Apolipoprotein B (apo B), a dietary lipid transporter, occurs as apo B-100 and apoB-48, created by a premature stop codon by apo B mRNA-editing enzyme
Autor:
Konstantin Adamsky, Gideon Rechavi, Carina Levin, Orly Weizer-Stern, Stefano Rivella, Ariel Koren, Laura Breda, William Breuer, Eliezer A. Rachmilewitz, Ninette Amariglio, Z. Ioav Cabantchik
Publikováno v:
British Journal of Haematology. 135:129-138
Beta-thalassaemia represents a group of diseases, in which ineffective erythropoiesis is accompanied by iron overload. In a mouse model of beta-thalassaemia, we observed that the liver expressed relatively low levels of hepcidin, which is a key facto
Autor:
Adina Bar-Haim, Ibrahim Abu-Kishk, Orly Weizer-Stern, Matitiahu Berkovitch, Lee H. Goldstein, Yariv Siman-Tov, Eran Kozer, Moshe Rechavi, Gideon Rechavi, Michal Toledano
Publikováno v:
The American journal of emergency medicine. 27(7)
Background Hepcidin regulates extracellular iron concentration by inhibiting iron release from macrophages and preventing iron absorption in the intestine. Our objective was to evaluate the expression of hepcidin in the liver in acute iron poisoning
Autor:
Ofer Margalit, David Givol, Orly Weizer-Stern, Ninette Amariglio, Konstantin Adamsky, Osnat Ashur-Fabian, Gideon Rechavi
Publikováno v:
British journal of haematology. 138(2)
Hepcidin is an iron-regulatory protein that is upregulated in response to increased iron or inflammatory stimuli. Hepcidin reduces serum iron and induces iron sequestration in the reticuloendothelial macrophages - the hallmark of anaemia of inflammat
Autor:
Eliezer A. Rachmilewitz, Orly Weizer-Stern, Stefano Rivella, Laura Breda, Gideon Rechavi, Konstantin Adamsky, Ninette Amariglio
Publikováno v:
American journal of hematology. 81(7)
beta-Thalassemia is an inherited anemia in which synthesis of the hemoglobin beta-chain is decreased. The excess unmatched alpha-globin chains accumulate in the growing erythroid precursors, causing their premature death (ineffective erythropoiesis).
Autor:
Gideon Rechavi, Eliezer A. Rachmilewitz, Ninette Amariglio, Orly Weizer-Stern, Z. Ioav Cabantchik, Konstantin Adamsky, Laura Breda, Stefano Rivella
Publikováno v:
Annals of the New York Academy of Sciences. 1054
The pathophysiology of thalassemia is, to a certain extent, associated with the generation of labile iron in the pathological red blood cell (RBC). The appearance of such forms of iron at the inner and outer cell surfaces exposes the cell to conditio
Autor:
Orly Weizer-Stern, Sara Gardenghi, Ninette Amariglio, Konstantin Adamsky, Gideon Rechavi, Ella Guy, Stefano Rivella, Laura Breda, Patricia J. Giardina, Eliezer A. Rachmilewitz, Robert W. Grady
Publikováno v:
Annals of the New York Academy of Sciences. 1054
To develop new treatments for beta-thalassemia, it is essential to identify the genes involved in the relevant pathophysiological processes. Iron metabolism in thalassemia mice being investigated, focusing on the expression of a gene called hepcidin
Autor:
Ariel Koren, Konstantin Adamsky, Stefano Rivella, Ninette Amariglio, Gideon Rechavi, Carina Levin, William Breuer, Eliezer A. Rachmilewitz, Sara Gardenghi, Yoav Zvi Cabantchik, Orly Weizer-Stern
Publikováno v:
Blood. 108:1556-1556
β-thalassaemia represents a group of diseases, in which ineffective erythropoiesis is accompanied by iron overload. In a mouse model of β-thalassaemia we observed that the liver expresses relatively low levels of hepcidin, which is a key factor in
Autor:
Ninette Amariglio, Robert W. Grady, Stefano Rivella, Patricia J. Giardina, Konstantin Adamsky, Ella Guy, Gideon Rechavi, Orly Weizer-Stern, Sara Gardenghi, Laura Breda, Eliezer A. Rachmilewitz
Publikováno v:
Blood. 106:3846-3846
We generated the first transplantable adult mouse models of beta-thalassemia intermedia and major by infusing mouse hematopoietic-fetal-liver cells (HFLC) heterozygous or homozygous for a deletion of the beta-globin gene (respectively with th3/+ and
Autor:
Orly Weizer‐Stern, Konstantin Adamsky, Ninette Amariglio, Eliezer Rachmilewitz, Laura Breda, Stefano Rivella, Gideon Rechavi
Publikováno v:
American Journal of Hematology; Jul2006, Vol. 81 Issue 7, p479-483, 5p