Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Orly Laufman"'
Autor:
Or Gozani, Jan E. Carette, Jeffrey R. Johnson, Peter Sarnow, Erik Verschueren, Jonathan Diep, Harry B. Greenberg, Tracy Young, Eileen Foy, Kristi J. Kobluk, James Zengel, Raul Andino, Christine E. Peters, Kuo-Feng Weng, Jiewei Xu, Alex W. Wilkinson, Ruth Hüttenhain, Siyuan Ding, Nevan J. Krogan, Gwendolyn M. Jang, Joshua E. Elias, Yaw Shin Ooi, Orly Laufman, Claude M. Nagamine
Publikováno v:
Nature microbiology, vol 4, iss 12
Nature microbiology
Nature microbiology
Enteroviruses (EVs) comprise a large genus of positive-sense, single-stranded RNA viruses whose members cause a number of important and widespread human diseases, including poliomyelitis, myocarditis, acute flaccid myelitis and the common cold. How E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73230660466375e76f25ef7276487c26
https://escholarship.org/uc/item/4xj9w0zf
https://escholarship.org/uc/item/4xj9w0zf
Publikováno v:
Cell Host Microbe
Cell, vol 178, iss 2
Cell, vol 178, iss 2
Positive-stranded RNA viruses extensively remodel host cell architecture to enable viral replication. Here, we examined the poorly understood formation of specialized membrane compartments that are critical sites for the synthesis of the viral genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f34ac822def9ce96a8018e8509ceae
https://pubmed.ncbi.nlm.nih.gov/31415743
https://pubmed.ncbi.nlm.nih.gov/31415743
Autor:
Gwendolyn M. Jang, Billy W. Newton, Laurence G. Webb, Vinod Balasubramaniam, Laura Satkamp, Gabriel N. Iglesias, Holly Ramage, Tongtong Zhu, Ana Fernandez-Sesma, Nichole Link, Erica Stevenson, Marine J. Petit, Michel Tassetto, Leila Shokat, Raul Andino, Katherine S. Pollard, Jack Taunton, Phillip P. Sharp, Amanda Everitt, Nevan J. Krogan, Hugo J. Bellen, Danielle L. Swaney, Andrea V. Gamarnik, John Von Dollen, Sara Cherry, Ivan Marazzi, Sebastian Aguirre, Priya S. Shah, A. Jeremy Willsey, Michael Shales, Orly Laufman, Ruth Hüttenhain, Tierney Baum, Jeffrey R. Johnson, Shashank Tripathi, Adolfo García-Sastre
Publikováno v:
Cell, vol 175, iss 7
Mosquito-borne flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), are a growing public health concern. Systems-level analysis of how flaviviruses hijack cellular processes through virus-host protein-protein interactions (PPIs) provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064ada14fddd2e505d4d98cf309f88f6
https://doi.org/10.1016/j.cell.2018.11.028
https://doi.org/10.1016/j.cell.2018.11.028
Publikováno v:
Traffic. 14:1065-1077
Multiple mutations in different subunits of the tethering complex Conserved Oligomeric Golgi (COG) have been identified as a cause for Congenital Disorders of Glycosylation (CDG) in humans. Yet, the mechanisms by which COG mutations induce the pleiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8e8952fdb583a30d518135a3b484042
https://doi.org/10.1111/tra.12093
https://doi.org/10.1111/tra.12093
Publikováno v:
The Journal of Cell Biology
The conserved oligomeric Golgi (COG) complex interacts with the t-SNARE Syntaxin 6 and promotes endosome-to-TGN retrograde trafficking.
The conserved oligomeric Golgi (COG) complex has been implicated in the regulation of endosome to trans-Golgi
The conserved oligomeric Golgi (COG) complex has been implicated in the regulation of endosome to trans-Golgi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b268cd314778b206097b784a0e816f43
https://doi.org/10.1083/jcb.201102045
https://doi.org/10.1083/jcb.201102045
Publikováno v:
The EMBO Journal. 28:2006-2017
The crucial roles of Sec1/Munc18 (SM)-like proteins in membrane fusion have been evidenced in genetic and biochemical studies. SM proteins interact directly with SNAREs and contribute to SNARE pairing by a yet unclear mechanism. Here, we show that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c121a3fea90160466828f79f5338e2a6
https://doi.org/10.1038/emboj.2009.168
https://doi.org/10.1038/emboj.2009.168
Autor:
Dmitry N. Kaluzhny, Olga F. Borisova, Edward N. Timofeev, Anna K. Shchyolkina, Orly Laufman, Haim Manor
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 23:257-265
Translin is a human single-stranded DNA and RNA binding protein that has been highly conserved in eukaryotic evolution. It consists of eight subunits having a highly helical secondary structure that assemble into a ring. The DNA and the RNA are bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cb173017a54c91d76131efcd6d361c
https://doi.org/10.1080/07391102.2005.10507064
https://doi.org/10.1080/07391102.2005.10507064
Publikováno v:
Nucleic Acids Research
Translin is a human octameric protein that specifically binds the single-stranded microsatellite repeats d(GT)n and the corresponding transcripts (GU)n. It also binds, with lesser affinities, other single-stranded G-rich DNA and RNA sequences. TRAX i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f11814477c28f5d881067e07138c03d
https://doi.org/10.1093/nar/gki727
https://doi.org/10.1093/nar/gki727
Autor:
Nancy Gavert, Sima Lev, Omer Keinan, SoHui Kim, Orly Laufman, Michael Selitrennik, Amir Kedan, Merav Marom
Publikováno v:
EMBO reports. 14(10)
Phosphatidic acid (PA) and phosphoinositides are metabolically interconverted lipid second messengers that have central roles in many growth factor (GF)-stimulated signalling pathways. Yet, little is known about the mechanisms that coordinate their p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908d8a9513f0a70db10638711cface75
https://pubmed.ncbi.nlm.nih.gov/23897088
https://pubmed.ncbi.nlm.nih.gov/23897088