Pristane-induced arthritis loci interact with the Slc11a1 gene to determine susceptibility in mice selected for high inflammation.

Autor: Marcelo De Franco, Luciana C Peters, Mara A Correa, Antonella Galvan, Tatiane Canhamero, Andrea Borrego, José R Jensen, Jussara Gonçalves, Wafa H K Cabrera, Nancy Starobinas, Orlando G Ribeiro, Tommaso A Dragani, Olga M Ibañez

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e88302 (2014)

AIRmax (maximal inflammation) and AIRmin (minimal inflammation) mice show distinct susceptibilities to pristane-induced arthritis (PIA). The Slc11a1 gene, which regulates macrophage and neutrophil activity, is involved in this infirmity. AIRmax (SS)

Externí odkaz: https://doaj.org/article/bc537b0914ba49758abf3f72e08c409f

Pain and Cellular Migration Induced by Bothrops jararaca Venom in Mice Selected for an Acute Inflammatory Response: Involvement of Mast Cells

Autor: Fernanda V. Kondo, Wafa H. K. Cabrera, Orlando G. Ribeiro, Marcelo De Franco, José Ricardo Jensen, Gisele Picolo, Morena B. Sant’Anna, Monica Spadafora-Ferreira, Andrea Borrego, Olga M. Ibañez, Nancy Starobinas

Publikováno v: Frontiers in Immunology, Vol 12 (2022)

Bothrops jararaca venom (BjV) can induce mast cell degranulation. In order to investigate the role of mast cells and the interference of the host genetic background in the inflammation induced by BjV, we have used mouse strains selected for maximal (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f82d099efb16a7dce715143fe6680e
https://doi.org/10.3389/fimmu.2021.779473

The Crotoxin:SBA-15 Complex Down-Regulates the Incidence and Intensity of Experimental Autoimmune Encephalomyelitis Through Peripheral and Central Actions

Autor: Morena Brazil Sant'Anna, Aline C. Giardini, Marcio A. C. Ribeiro, Flavia S. R. Lopes, Nathalia B. Teixeira, Louise F. Kimura, Michelle C. Bufalo, Orlando G. Ribeiro, Andrea Borrego, Wafa H. K. Cabrera, Julio C. B. Ferreira, Vanessa O. Zambelli, Osvaldo A. Sant'Anna, Gisele Picolo

Publikováno v: Frontiers in Immunology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Immunology, Vol 11 (2020)

Crotoxin (CTX), the main neurotoxin from Crotalus durissus terrificus snake venom, has anti-inflammatory, immunomodulatory and antinociceptive activities. However, the CTX-induced toxicity may compromise its use. Under this scenario, the use of nanop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9a8f3f8aa1a06efb7420767901fe52
http://europepmc.org/articles/PMC7655790

The role of leukotriene B4 in early stages of experimental paracoccidioidomycosis induced in phenotypically selected mouse strains

Autor: Silvio Luis de Oliveira, Ângela Maria Victoriano de Campos Soares, Orlando G. Ribeiro, Helanderson de Almeida Balderramas

Publikováno v: Medical Mycology. 51:625-634

Paracoccidioidomycosis is a human systemic mycosis caused by the fungus Paracoccidioides brasiliensis. The mechanisms involved in innate immune response to this fungus are not fully elucidated. Leukotrienes are known to be critical for the clearance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa1bcb184ab12958efe35102ec118e1
https://doi.org/10.3109/13693786.2013.777163

Polygenic control of quantitative antibody responsiveness: restrictions of the multispecific effect related to the selection antigen

Autor: Guido Biozzi, M. Siqueira, Silvio L. Oliveira, Rosa Maria Piatti, Osvaldo A. Sant'Anna, Olga M. Ibañez, Orlando G. Ribeiro Fihlo, Denise Mouton, Solange Massa

Publikováno v: Immunogenetics. 28:6-12

Among the differences observed between the various high (H) and low (L) antibody responder lines of mice resulting from distinct bidirectional selective breedings, one of the most puzzling is the variation in the “multispecific effect,” i. e., in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c692bf36383058ea40e98fc75c2dc1
https://doi.org/10.1007/bf00372523