Diabetes medications as potential calorie restriction mimetics-a focus on the alpha-glucosidase inhibitor acarbose.

Autor: Smith DL Jr; Department of Nutrition Sciences, University of Alabama at Birmingham, 1720 2nd Avenue S, Webb 423, Birmingham, AL, 35294-3360, USA. dsmithjr@uab.edu.; Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL, USA. dsmithjr@uab.edu.; Integrative Center for Aging Research, University of Alabama at Birmingham, Birmingham, AL, USA. dsmithjr@uab.edu.; Nathan Shock Center of Excellence in the Biology of Aging, University of Alabama at Birmingham, Birmingham, AL, USA. dsmithjr@uab.edu.; Diabetes Research Center, University of Alabama at Birmingham, Birmingham, AL, USA. dsmithjr@uab.edu., Orlandella RM; Graduate Biomedical Sciences, University of Alabama at Birmingham, Birmingham, AL, USA., Allison DB; School of Public Health, Indiana University - Bloomington, Bloomington, IN, USA., Norian LA; Department of Nutrition Sciences, University of Alabama at Birmingham, 1720 2nd Avenue S, Webb 423, Birmingham, AL, 35294-3360, USA.; Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.

Publikováno v: GeroScience [Geroscience] 2021 Jun; Vol. 43 (3), pp. 1123-1133. Date of Electronic Publication: 2020 Oct 02.

Obesity diminishes response to PD-1-based immunotherapies in renal cancer.

Autor: Boi SK; Graduate Biomedical Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Orlandella RM; Graduate Biomedical Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Gibson JT; Graduate Biomedical Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Turbitt WJ; Department of Nutrition Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Wald G; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Thomas L; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Buchta Rosean C; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Norris KE; Honors Undergraduate Research Program, School of Health Professions, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Bing M; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Bertrand L; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Gross BP; Interdisciplinary Program in Immunology, The University of Iowa, Iowa City, Iowa, USA., Makkouk A; Interdisciplinary Program in Immunology, The University of Iowa, Iowa City, Iowa, USA., Starenki D; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA., Farag KI; Science and Technology Honors Program, College of Arts and Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Sorge RE; Department of Psychology, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Brown JA; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA.; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA., Gordetsky J; Departments of Pathology and Urology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Yasin H; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.; Department of Internal Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Garje R; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.; Genitourinary Oncology Program, Division of Hematology, Oncology and Blood and Marrow Transplantation, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Nandagopal L; Division of Hematology and Oncology, The University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA.; The University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, Alabama, USA., Weiner GJ; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.; Department of Internal Medicine, Division of General Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Lubaroff DM; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA.; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA., Arend RC; The University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, Alabama, USA.; Department of Obstetrics and Gynecology, The University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA., Li P; Department of Biostatistics, The University of Alabama at Birmingham School of Nursing, Birmingham, Alabama, USA., Zakharia Y; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.; Genitourinary Oncology Program, Division of Hematology, Oncology and Blood and Marrow Transplantation, The University of Iowa, Iowa City, Iowa, USA., Yang E; The University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, Alabama, USA.; Department of Radiation Oncology, The University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA., Salem AK; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.; Division of Pharmaceutics and Translational Therapeutics, University of Iowa College of Pharmacy, Iowa City, Iowa, USA., Nepple K; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA.; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA., Marquez-Lago TT; Department of Genetics, The University of Alabama at Birmingham, Birmingham, Alabama, USA.; Department of Cell, Developmental and Integrative Biology, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Norian LA; Department of Nutrition Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA lnorian@uab.edu.; The University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, Alabama, USA.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2020 Dec; Vol. 8 (2).

Obesity-Associated Myeloid-Derived Suppressor Cells Promote Apoptosis of Tumor-Infiltrating CD8 T Cells and Immunotherapy Resistance in Breast Cancer.

Autor: Gibson JT; Graduate Biomedical Sciences, University of Alabama at Birmingham, Birmingham, AL, United States., Orlandella RM; Graduate Biomedical Sciences, University of Alabama at Birmingham, Birmingham, AL, United States., Turbitt WJ; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, United States., Behring M; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, United States., Manne U; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, United States.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, United States., Sorge RE; Department of Psychology, University of Alabama at Birmingham, Birmingham, AL, United States.; Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL, United States., Norian LA; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, United States.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, United States.; Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2020 Oct 06; Vol. 11, pp. 590794. Date of Electronic Publication: 2020 Oct 06 (Print Publication: 2020).

Body fat indices and survival in immunotherapy-treated patients with cancer.

Autor: Orlandella RM; Graduate Biomedical Sciences, University of Alabama at Birmingham, Birmingham, Alabama., Bail JR; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama., Behring M; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama., Halilova KI; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama., Johnson R; Department of Sociology, University of Alabama at Birmingham, Birmingham, Alabama., Williams V; Department of Health Behavior, University of Alabama at Birmingham, Birmingham, Alabama., Norian LA; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama., Demark-Wahnefried W; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama.

Publikováno v: Cancer [Cancer] 2020 Jul 01; Vol. 126 (13), pp. 3156-3157. Date of Electronic Publication: 2020 Apr 14.

Effects of diet on immune cells within the central nervous system.

Autor: Totsch SK; Department of Psychology, University of Alabama at Birmingham, AL, USA., Meir RY; Department of Psychology, University of Alabama at Birmingham, AL, USA., Orlandella RM; Graduate Biomedical Sciences, Nutrition Obesity Research Center, University of Alabama at Birmingham, AL, USA., Norian LA; Department of Nutrition Sciences, Comprehensive Cancer Center, Nutrition Obesity Research Center, University of Alabama at Birmingham, AL, USA., Sorge RE; Department of Psychology, University of Alabama at Birmingham, AL, USA. Electronic address: rsorge@uab.edu.

Publikováno v: Physiology & behavior [Physiol Behav] 2018 Nov 01; Vol. 196, pp. 158-164. Date of Electronic Publication: 2018 Sep 03.