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pro vyhledávání: '"Orla K. Mc Carthy"'
Autor:
Alex Musso Buendía, Alessandro Schipani, Dolores Gonzalez Pacanowska, Orla K. Mc Carthy, Luis M. Ruiz-Pérez, Reto Brun, Marcel Kaiser, Ian H. Gilbert
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:3809-3812
Potential inhibitors of the Trypanosoma cruzi dUTP nucleotidohydrolase were docked into the enzyme using the program FlexX. Compounds that docked selectively were then selected and synthesized using solid phase methodology, giving rise to a novel lib