Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Orla Casey"'
Autor:
Lauren Brady, Jessica Carlsson, Anne-Marie Baird, Orla Casey, Tatjana Vlajnic, Pierre Murchan, David Cormican, Danielle Costigan, Steven Gray, Orla Sheils, Amanda O'Neill, R. William Watson, Ove Andren, Stephen Finn
Publikováno v:
Cancer Treatment and Research Communications, Vol 29, Iss , Pp 100451- (2021)
Introduction: Prostate cancer is a heterogeneous disease, with a complex molecular landscape that evolves throughout disease progression. Common alterations in genes such as ERG and PTEN have been attributed to worse prognosis. This study aimed to fu
Externí odkaz:
https://doaj.org/article/869ace08d9a3453a91cb1d1b38d5ae20
Autor:
Lauren Brady, Brian Hayes, Gráinne Sheill, Anne-Marie Baird, Emer Guinan, Bryan Stanfill, Tatjana Vlajnic, Orla Casey, Verena Murphy, John Greene, Emma H Allott, Juliette Hussey, Fidelma Cahill, Mieke Van Hemelrijck, Nicola Peat, Lorelei Mucci, Moya Cunningham, Liam Grogan, Thomas Lynch, Rustom P Manecksha, John McCaffrey, Dearbhaile O'Donnell, Orla Sheils, John O'Leary, Sarah Rudman, Ray McDermott, Stephen Finn
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243928 (2020)
BackgroundCirculating tumour cells (CTCs) represent a morphologically distinct subset of cancer cells, which aid the metastatic spread. The ExPeCT trial aimed to examine the effectiveness of a structured exercise programme in modulating levels of CTC
Externí odkaz:
https://doaj.org/article/f01f65e4dcf04888b2513efc808b130d
Autor:
Gráinne Sheill, Lauren Brady, Emer Guinan, Brian Hayes, Orla Casey, John Greene, Tatjana Vlajnic, Fidelma Cahill, Mieke Van Hemelrijck, Nicola Peat, Sarah Rudman, Juliette Hussey, Moya Cunningham, Liam Grogan, Thomas Lynch, Rustom P. Manecksha, John McCaffrey, Lorelei Mucci, Orla Sheils, John O’Leary, Dearbhaile M. O’Donnell, Ray McDermott, Stephen Finn
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Prostate cancer (PrCa) is the second most common cancer in Ireland. Many men present with locally advanced or metastatic cancer for whom curative surgery is inappropriate. Advanced cancer patients are encouraged to remain physical
Externí odkaz:
https://doaj.org/article/725cf7bfec2440df872780a14be30246
Autor:
Gráinne Sheill, Lauren Brady, Brian Hayes, Anne-Marie Baird, Emer Guinan, Rishabh Vishwakarma, Caroline Brophy, Tatjana Vlajnic, Orla Casey, Verena Murphy, John Greene, Emma Allott, Juliette Hussey, Fidelma Cahill, Mieke Van Hemelrijck, Nicola Peat, Lorelei Mucci, Moya Cunningham, Liam Grogan, Thomas Lynch, Rustom P. Manecksha, John McCaffrey, Dearbhaile O’Donnell, Orla Sheils, John O’Leary, Sarah Rudman, Ray McDermott, Stephen Finn
Publikováno v:
Sheill, G, Brady, L, Hayes, B, Baird, A-M, Guinan, E, Vishwakarma, R, Brophy, C, Vlajnic, T, Casey, O, Murphy, V, Greene, J, Allott, E, Hussey, J, Cahill, F, Van Hemelrijck, M, Peat, N, Mucci, L, Cunningham, M, Grogan, L, Lynch, T, Manecksha, R P, McCaffrey, J, O'Donnell, D, Sheils, O, O'Leary, J, Rudman, S, McDermott, R & Finn, S 2023, ' ExPeCT: a randomised trial examining the impact of exercise on quality of life in men with metastatic prostate cancer ', Supportive Care in Cancer, vol. 31, no. 5, 292 . https://doi.org/10.1007/s00520-023-07740-4
Purpose All patients living with cancer, including those with metastatic cancer, are encouraged to be physically active. This paper examines the secondary endpoints of an aerobic exercise intervention for men with metastatic prostate cancer. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e0338328689323a3db82f84b68a162
https://pure.qub.ac.uk/en/publications/1fa7f6e0-5759-4038-956f-f8aba9536dc5
https://pure.qub.ac.uk/en/publications/1fa7f6e0-5759-4038-956f-f8aba9536dc5
Autor:
Dearbhaile M. O'Donnell, Juliette Hussey, Jean Dunne, Thomas R. Lynch, Stephen P. Finn, Brian D. Hayes, John Greene, Nicola Peat, John J. O'Leary, Emma H. Allott, Rustom P. Manecksha, Sarah Rudman, Moya Cunningham, Orla Casey, Grainne Sheill, Lauren Brady, Emer Guinan, Liam Grogan, John McCaffrey, Mieke Van Hemelrijck, Anne-Marie Baird, Tatjana Vlajnic, Bryan Stanfill, Fidelma Cahill, Lorelei A. Mucci, Ray McDermott, Orla Sheils, Dean Holden, Verena Murphy
Publikováno v:
Cancers
Hayes, B, Brady, L, Sheill, G, Baird, A-M, Guinan, E, Stanfill, B, Dunne, J, Holden, D, Vlajnic, T, Casey, O, Murphy, V, Greene, J, Allott, E H, Hussey, J, Cahill, F, Hemelrijck, M V, Peat, N, Mucci, L A, Cunningham, M, Grogan, L, Lynch, T, Manecksha, R P, McCaffrey, J, O’Donnell, D M, Sheils, O, O’Leary, J J, Rudman, S, McDermott, R & Finn, S 2021, ' Circulating Tumour Cell Numbers Correlate with Platelet Count and Circulating Lymphocyte Subsets in Men with Advanced Prostate Cancer: Data from the ExPeCT Clinical Trial (CTRIAL-IE 15-21) ', Cancers, vol. 13, no. 18, 4690 . https://doi.org/10.3390/cancers13184690
Cancers, Vol 13, Iss 4690, p 4690 (2021)
Volume 13
Issue 18
Hayes, B, Brady, L, Sheill, G, Baird, A-M, Guinan, E, Stanfill, B, Dunne, J, Holden, D, Vlajnic, T, Casey, O, Murphy, V, Greene, J, Allott, E H, Hussey, J, Cahill, F, Hemelrijck, M V, Peat, N, Mucci, L A, Cunningham, M, Grogan, L, Lynch, T, Manecksha, R P, McCaffrey, J, O’Donnell, D M, Sheils, O, O’Leary, J J, Rudman, S, McDermott, R & Finn, S 2021, ' Circulating Tumour Cell Numbers Correlate with Platelet Count and Circulating Lymphocyte Subsets in Men with Advanced Prostate Cancer: Data from the ExPeCT Clinical Trial (CTRIAL-IE 15-21) ', Cancers, vol. 13, no. 18, 4690 . https://doi.org/10.3390/cancers13184690
Cancers, Vol 13, Iss 4690, p 4690 (2021)
Volume 13
Issue 18
Interactions between circulating tumour cells (CTCs) and platelets are thought to inhibit natural killer(NK)-cell-induced lysis. We attempted to correlate CTC numbers in men with advanced prostate cancer with platelet counts and circulating lymphocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e155a5427a190a03d53f8504d56a4c3d
http://europepmc.org/articles/PMC8466183
http://europepmc.org/articles/PMC8466183
Autor:
Supreet Agarwal, Orla Casey, Wanhai Xu, Lei Fang, Aian Neil Alilin, Juan Juan Yin, Qi Yang, Michael L. Beshiri, Lechen Li, Amir H. Ameri, Ross Lake, Kathleen Kelly, Keith H. Jansson, Simeng Wang
Publikováno v:
Oncogene
Early growth response-1 (EGR1) is a transcription factor correlated with prostate cancer (PC) progression in a variety of contexts. For example, EGR1 levels increase in response to suppressed androgen receptor signaling or loss of the tumor suppresso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f980d21660cc458a58a8a280d97dbcc
https://doi.org/10.1038/s41388-019-0873-8
https://doi.org/10.1038/s41388-019-0873-8
Autor:
Steven G. Gray, Orla Sheils, Ove Andrén, Jessica Carlsson, Danielle C. Costigan, Stephen P. Finn, Pierre Murchan, Anne-Marie Baird, Lauren Brady, Tatjana Vlajnic, David Cormican, Amanda O'Neill, R. William G. Watson, Orla Casey
Publikováno v:
Cancer Treatment and Research Communications, Vol 29, Iss, Pp 100451-(2021)
Introduction Prostate cancer is a heterogeneous disease, with a complex molecular landscape that evolves throughout disease progression. Common alterations in genes such as ERG and PTEN have been attributed to worse prognosis. This study aimed to fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196726ab94be6f6497e5187fbde198c5
http://www.sciencedirect.com/science/article/pii/S2468294221001489
http://www.sciencedirect.com/science/article/pii/S2468294221001489
Autor:
John J. O'Leary, Orla Casey, Emma H. Allott, Sarah Rudman, John Greene, Anne-Marie Baird, John McCaffrey, Dearbhaile M. O'Donnell, Juliette Hussey, Fidelma Cahill, Stephen P. Finn, Thomas R. Lynch, Liam Grogan, Grainne Sheill, Lorelei A. Mucci, Ray McDermott, Tatjana Vlajnic, Brian D. Hayes, Verena Murphy, Orla Sheils, Nicola Peat, Rustom P. Manecksha, Moya Cunningham, Mieke Van Hemelrijck, Lauren Brady, Emer Guinan, Bryan Stanfill
Publikováno v:
Brady, L, Hayes, B, Sheill, G, Baird, A-M, Guinan, E, Stanfill, B, Vlajnic, T, Casey, O, Murphy, V, Greene, J, Allott, E H, Hussey, J, Cahill, F, Van Hemelrijck, M, Peat, N, Mucci, L, Cunningham, M, Grogan, L, Lynch, T, Manecksha, R P, McCaffrey, J, O'Donnell, D, Sheils, O, O'Leary, J, Rudman, S, McDermott, R & Finn, S 2020, ' Platelet cloaking of circulating tumour cells in patients with metastatic prostate cancer: Results from ExPeCT, a randomised controlled trial ', PLoS ONE, vol. 15, no. 12, e0243928 . https://doi.org/10.1371/journal.pone.0243928
PLoS ONE, Vol 15, Iss 12, p e0243928 (2020)
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0243928 (2020)
PLoS ONE
Background Circulating tumour cells (CTCs) represent a morphologically distinct subset of cancer cells, which aid the metastatic spread. The ExPeCT trial aimed to examine the effectiveness of a structured exercise programme in modulating levels of CT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e3350fcc067315c0779de29f3ca974
https://pure.qub.ac.uk/en/publications/platelet-cloaking-of-circulating-tumour-cells-in-patients-with-metastatic-prostate-cancer-results-from-expect-a-randomised-controlled-trial(8e8f9234-e025-4526-a2e0-7f19c23508ce).html
https://pure.qub.ac.uk/en/publications/platelet-cloaking-of-circulating-tumour-cells-in-patients-with-metastatic-prostate-cancer-results-from-expect-a-randomised-controlled-trial(8e8f9234-e025-4526-a2e0-7f19c23508ce).html
Autor:
Emily Hams, Anne-Marie Baird, Stephen P. Finn, John Greene, Martin P. Barr, John J. O'Leary, Padraic G. Fallon, Gordon Blackshields, Orla Casey, Paul Smyth, Orla Sheils, Stephen R. Pennington, Louise Flynn
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Prostate cancer accounts for approximately 13.5% of all newly diagnosed male cancer cases. Significant clinical burdens remain in terms of ineffective prognostication, with overtreatment of insignificant disease. Additionally, the pathobiology underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ea569288daa8e1ede291dd2c147f5a
https://pubmed.ncbi.nlm.nih.gov/32647229
https://pubmed.ncbi.nlm.nih.gov/32647229
Autor:
Orla Casey, Neil J. Rowan
Publikováno v:
Current Opinion in Environmental Science & Health. 21:100254
There is a pressing drive to address climate change and environmental degradation that are global existential threats. Europe has strategically responded by unifying efforts to transform its connected communities into a modern, resource-efficient and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da678d7ff0b6178ee379a3f3808e49c
https://doi.org/10.1016/j.coesh.2021.100254
https://doi.org/10.1016/j.coesh.2021.100254