Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Orkun Ok"'
Autor:
Anna Lechado-Terradas, Sandra Schepers, Katharina I. Zittlau, Karan Sharma, Orkun Ok, Julia C. Fitzgerald, Stefan Geimer, Benedikt Westermann, Boris Macek, Philipp J. Kahle
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 576-602 (2022)
PINK1/parkin-dependent mitophagy initially involves (phospho)ubiquitin-directed proteasome-dependent degradation of certain outer mitochondrial membrane (OMM) proteins (e.g. mitofusins) and the recruitment of autophagy adaptors to a group of ubiquiti
Externí odkaz:
https://doaj.org/article/28921611ba294240a516a15b1a04f119
Autor:
Evelien Van Schoor, Simona Ospitalieri, Sebastiaan Moonen, Sandra O. Tomé, Alicja Ronisz, Orkun Ok, Jochen Weishaupt, Albert C. Ludolph, Philip Van Damme, Ludo Van Den Bosch, Dietmar Rudolf Thal
Publikováno v:
Acta neuropathologica 144(3), 393-411 (2022). doi:10.1007/s00401-022-02466-9
Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of motor neurons in the motor cortex, brainstem, and spinal cord. Although ALS is considered a motor neuron disorder, neuroinflammation also plays an important role. Recent evid