Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Orkun Akin"'
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S45- (2023)
Externí odkaz:
https://doaj.org/article/591e26da602349c496178ad4fba4aca8
Autor:
Orkun Akin, S Lawrence Zipursky
Publikováno v:
eLife, Vol 5 (2016)
Axon guidance is proposed to act through a combination of long- and short-range attractive and repulsive cues. The ligand-receptor pair, Netrin (Net) and Frazzled (Fra) (DCC, Deleted in Colorectal Cancer, in vertebrates), is recognized as the prototy
Externí odkaz:
https://doaj.org/article/871d0d47889a4a43afbf02ed8683384f
Publikováno v:
PLoS Biology, Vol 7, Iss 9, p e1000201 (2009)
Eukaryotic cells assemble viscoelastic networks of crosslinked actin filaments to control their shape, mechanical properties, and motility. One important class of actin network is nucleated by the Arp2/3 complex and drives both membrane protrusion at
Externí odkaz:
https://doaj.org/article/062f82a3c05b48278b01f53d3d671112
Autor:
S. Lawrence Zipursky, Orkun Akin
Publikováno v:
Current Opinion in Genetics & Development. 65:8-13
It has long been appreciated that activity sculpts the formation of neuronal circuits in the mammalian brain. By contrast, in Drosophila it was generally thought that genetically hardwired mechanisms of development, mediated by cell recognition molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd108505e5e42e4efc33ea8ccfe663a5
https://doi.org/10.1016/j.gde.2020.04.005
https://doi.org/10.1016/j.gde.2020.04.005
Publikováno v:
Dev Neurobiol
Developmental neural activity is a common feature of neural circuit assembly. Although glia have established roles in synapse development, the contribution of neuron-glia interactions to developmental activity remains largely unexplored. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4dc2001a38ea7a07d5076fe2cada93
https://europepmc.org/articles/PMC9018619/
https://europepmc.org/articles/PMC9018619/
Autor:
Bryce T. Bajar, Nguyen T. Phi, Jesse Isaacman-Beck, Jun Reichl, Harpreet Randhawa, Orkun Akin
Publikováno v:
Nature
In vertebrates, stimulus-independent activity accompanies neural circuit maturation throughout the developing brain(1,2). The recent discovery of comparable activity in the developing Drosophila central nervous system (CNS) suggests that developmenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bc6705f61a7376efdf78b0acf00dc6
https://europepmc.org/articles/PMC9020639/
https://europepmc.org/articles/PMC9020639/
Autor:
Peter Bieling, Orkun Akin, Carl C. Hayden, R. Dyche Mullins, Scott D. Hansen, Daniel A. Fletcher, Tai-De Li
Publikováno v:
The EMBO Journal
WASP‐family proteins are known to promote assembly of branched actin networks by stimulating the filament‐nucleating activity of the Arp2/3 complex. Here, we show that WASP‐family proteins also function as polymerases that accelerate elongation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ad77bd8d58d872a85f30bb036108cb
https://doi.org/10.15252/embj.201797039
https://doi.org/10.15252/embj.201797039
Publikováno v:
Neuron, vol 101, iss 5
SummaryStereotyped synaptic connections define the neural circuits of the brain. In vertebrates, stimulus-independent activity contributes to neural circuit formation. It is unknown whether this type of activity is a general feature of nervous system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c5ee1211a209cdc8835838cf39d7d0
https://doi.org/10.1101/376871
https://doi.org/10.1101/376871
Publikováno v:
Turkish Journal of Electrical Power and Energy Systems, Vol 3, Iss 1, Pp 28-38 (2023)
Externí odkaz:
https://doaj.org/article/1e503377bd564a7f9c9e279a96799a65
Publikováno v:
Neuron. 82(2):320-333
Summary Neural circuit formation relies on interactions between axons and cells within the target field. While it is well established that target-derived signals act on axons to regulate circuit assembly, the extent to which axon-derived signals cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53fb66d6d407588225e73cc4f86c3d1d