Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Orit Shmueli"'
Autor:
Orit Shmueli, Maxim Shklar, Michael Shmoish, Marilyn Safran, Doron Lancet, Liora Strichman-Almashanu
Publikováno v:
Nucleic Acids Research
GeneCards is an automatically mined database of human genes that strives to create, along with its auxiliary databases--GeneLoc, GeneNote and GeneAnnot--the most inclusive resource of gene-centered information of the human genome. GeneTide, the Gene
Autor:
Vered Chalifa-Caspi, Maxim Shklar, Doron Lancet, Arren Bar-Even, Itai Yanai, Ron Ophir, Michael Shmoish, Shirley Horn-Saban, Orit Shmueli, Hila Benjamin, Marilyn Safran, Eytan Domany
Publikováno v:
Bioinformatics. 21:650-659
Motivation: Genes are often characterized dichotomously as either housekeeping or single-tissue specific. We conjectured that crucial functional information resides in genes with midrange profiles of expression. Results: To obtain such novel informat
Autor:
Ron Ophir, Hila Benjamin-Rodrig, Vered Chalifa-Caspi, Orit Shmueli, Eytan Domany, Doron Lancet, Shirley Horn-Saban, Marilyn Safran, Michael Shmoish
Publikováno v:
Comptes Rendus Biologies. 326:1067-1072
A novel data set, GeneNote (Gene Normal Tissue Expression), was produced to portray complete gene expression profiles in healthy human tissues using the Affymetrix GeneChip HG-U95 set, which includes 62 839 probe-sets. The hybridization intensities o
Autor:
Ron Ophir, Pavel Kats, Marilyn Safran, Itai Yanai, Naomi Rosen, Hila Benjamin-Rodrig, Doron Lancet, Vered Chalifa-Caspi, Michael Shmoish, Orit Shmueli
Publikováno v:
Briefings in Bioinformatics. 4:349-360
The interpretation of microarray expression results often includes extensive efforts to identify and annotate the gene representatives immobilised on the arrays. In this paper we describe the usage of our automatic GeneAnnot system, which links betwe
Autor:
Orly Reiner, Orit Shmueli
Publikováno v:
Scopus-Elsevier
We have isolated the chicken LIS1 homolog, chLIS1, with DNA sequence similarity of over 68% to the human cDNA and 99% amino acid identity. Additionally, we describe the pattern of chLIS1 expression in the chicken embryo. The early embryonic expressio
Autor:
Aviv Cahana, Orly Reiner, Elizabeth A. Lindsay, Antonio Baldini, David H. Ledbetter, Orit Shmueli, Irit Bar-Am, Tamar Sapir, Romeo Carrozzo
Publikováno v:
Genomics. 30:251-256
We report here the isolation of a novel cDNA, designated LIS2, that maps to chromosome 2p11.2 by in situ hybridization and demonstrates extremely high sequence similarity to the recently identified LIS1 gene involved in Miller–Dieker lissencephaly
Autor:
Vered Chalifa-Caspi, Marilyn Safran, Naomi Rosen, Orit Shmueli, Julie Stampnitzky, Doron Lancet, Michal Lapidot, Avital Adato
Publikováno v:
ISMB (Supplement of Bioinformatics)
Motivation:Despite the numerous available whole-genome mapping resources, no comprehensive, integrated map of the human genome yet exists. Results: GeneLoc, software adjunct to GeneCards and UDB, integrates gene lists by comparing genomic coordinates
Autor:
Ron Ophir, V. Chalifa-Casp, Orit Shmueli, Doron Lancet, Michael Shmoish, Naomi Rosen, Hila Benjamin-Rodrig, Marilyn Safran, Itai Yanai
Publikováno v:
Computational Systems Bioinformatics. CSB2003. Proceedings of the 2003 IEEE Bioinformatics Conference. CSB2003.
The popular GeneCards/spl trade/ integrated database of human genes, genomic maps, proteins and diseases has recently spawned three related functional genomics efforts. As sequence data rapidly accumulates, the bottleneck in biology shifts from data
GeneAnnot: comprehensive two-way linking between oligonucleotide array probesets and GeneCards genes
Autor:
Doron Lancet, Orit Shmueli, Tsippi Iny Stein, Vered Chalifa-Caspi, Maxim Shklar, Itai Yanai, Michael Shmoish, Marilyn Safran, Hila Benjamin-Rodrig, Ron Ophir, Naomi Rosen
Publikováno v:
Bioinformatics (Oxford, England). 20(9)
Motivation: High density oligonucleotide arrays are usually annotated in a one-to-one fashion, with each probeset assigned to one gene. However, in reality, subsets of oligonucleotides in a probeset may match sequences within more than one gene, pote
Human Gene-Centric Databases at the Weizmann Institute of Science: GeneCards, UDB, CroW 21 and HORDE
Autor:
Michael Shmoish, Tal Atarot, Tsviya Olender, Avital Adato, Naomi Rosen, Yoram Groner, Marilyn Safran, Inga Peter, Gustavo Glusman, Vered Chalifa-Caspi, Miriam Khen, Doron Lancet, Ester Feldmesser, Yakov Peter, Orit Shmueli, Michal Lapidot
Publikováno v:
Nucleic acids research. 31(1)
Recent enhancements and current research in the GeneCards (GC) (http://bioinfo.weizmann.ac.il/cards/) project are described, including the addition of gene expression profiles and integrated gene locations. Also highlighted are the contributions of s