Zobrazeno 1 - 10
of 295
pro vyhledávání: '"Orit Jacobson"'
Autor:
Wei Tang, Zhen Yang, Liangcan He, Liming Deng, Parinaz Fathi, Shoujun Zhu, Ling Li, Bo Shen, Zhantong Wang, Orit Jacobson, Jibin Song, Jianhua Zou, Ping Hu, Min Wang, Jing Mu, Yaya Cheng, Yuanyuan Ma, Longguang Tang, Wenpei Fan, Xiaoyuan Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Tumor hypoxia is a major limitation in radiotherapy, and strategies to address this often fail due to high oxygen consumption. Here, the authors report a nanomaterial assembly for the simultaneous reduction in mitochondrial respiration and to supply
Externí odkaz:
https://doaj.org/article/1c58c1e0a770416a88be21da7c575243
Early stratification of radiotherapy response by activatable inflammation magnetic resonance imaging
Autor:
Zijian Zhou, Hongzhang Deng, Weijing Yang, Zhantong Wang, Lisen Lin, Jeeva Munasinghe, Orit Jacobson, Yijing Liu, Longguang Tang, Qianqian Ni, Fei Kang, Yuan Liu, Gang Niu, Ruiliang Bai, Chunqi Qian, Jibin Song, Xiaoyuan Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Non-invasive approaches to stratify early responses to therapy are of great value to improve cancer patient management. Here the authors design a hybrid nanovesicle-based activatable inflammation magnetic resonance method for the early prediction of
Externí odkaz:
https://doaj.org/article/db7e34283bc34e708ee282374047349e
Autor:
Sheng Wang, Guocan Yu, Weijing Yang, Zhantong Wang, Orit Jacobson, Rui Tian, Hongzhang Deng, Lisen Lin, Xiaoyuan Chen
Publikováno v:
Advanced Science, Vol 8, Iss 10, Pp n/a-n/a (2021)
Abstract Nanomedicines with photodynamic therapy and reactive oxygen species (ROS)‐triggered drug release capabilities are promising for cancer therapy. However, most of the nanomedicines based on ROS‐responsive nanocarriers still suffer from ser
Externí odkaz:
https://doaj.org/article/d26c93eea9d3495a9f88106ac458806b
Autor:
Wenpei Fan, Nan Lu, Zheyu Shen, Wei Tang, Bo Shen, Zhaowen Cui, Lingling Shan, Zhen Yang, Zhantong Wang, Orit Jacobson, Zijian Zhou, Yijing Liu, Ping Hu, Weijing Yang, Jibin Song, Yang Zhang, Liwen Zhang, Niveen M. Khashab, Maria A. Aronova, Guangming Lu, Xiaoyuan Chen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
A common failure of many cancer treatments is attributed to the resistance imparted by tumour hypoxia. Here, the authors report on the generic synthesis of small-sized hollow mesoporous organosilica nanoparticles which are designed for oxygen-indepen
Externí odkaz:
https://doaj.org/article/a33428d6ae6947ed8bb47a3b9835cc6e
Autor:
Guocan Yu, Zhen Yang, Xiao Fu, Bryant C. Yung, Jie Yang, Zhengwei Mao, Li Shao, Bin Hua, Yijing Liu, Fuwu Zhang, Quli Fan, Sheng Wang, Orit Jacobson, Albert Jin, Changyou Gao, Xiaoying Tang, Feihe Huang, Xiaoyuan Chen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Multifunctional nanomedicine platforms are highly promising for anticancer therapy. Here, the authors design polyrotaxane-based theranostic nanoparticles that combine targeted drug delivery with photothermal behaviour to exhibit potent anti-tumour ef
Externí odkaz:
https://doaj.org/article/55dabb77adbd469d974b5bb85b4ec0e7
Autor:
Guizhi Zhu, Geoffrey M. Lynn, Orit Jacobson, Kai Chen, Yi Liu, Huimin Zhang, Ying Ma, Fuwu Zhang, Rui Tian, Qianqian Ni, Siyuan Cheng, Zhantong Wang, Nan Lu, Bryant C. Yung, Zhe Wang, Lixin Lang, Xiao Fu, Albert Jin, Ido D. Weiss, Harshad Vishwasrao, Gang Niu, Hari Shroff, Dennis M. Klinman, Robert A. Seder, Xiaoyuan Chen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Albumin conjugates can enhance drug delivery. Here, the authors repurpose albumin-binding Evans blue to develop nanovaccines that co-deliver adjuvants and tumor neoantigens to antigen-presenting cells in lymph nodes, resulting in potent and durable a
Externí odkaz:
https://doaj.org/article/6c1cbd8acb2f42149db4a8201852deb6
Autor:
Guizhi Zhu, Lei Mei, Harshad D. Vishwasrao, Orit Jacobson, Zhantong Wang, Yijing Liu, Bryant C. Yung, Xiao Fu, Albert Jin, Gang Niu, Qin Wang, Fuwu Zhang, Hari Shroff, Xiaoyuan Chen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nucleic acid nanomedicines are promising for cancer drug delivery. Here, the authors show using a mouse model the tumor immunotherapeutic efficacy of nanovaccines based on intertwining DNA-RNA nanocapsules loaded with DNA CpG, Stat3-silencing short h
Externí odkaz:
https://doaj.org/article/c51e8ed297cd4c9da385abee4fc19f46
Autor:
Xiaoyuan Chen, Qin Lin, Hua Wu, Long Sun, Xianzhong Zhang, Orit Jacobson, Xuejun Wen, Weixi Guo, Li Fu, Lanling Yao, Kaili Fu, Zhide Guo, Haojun Chen, Liang Zhao
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170eaf534417765ef8b6f9c614672487
https://doi.org/10.1158/1535-7163.22519245.v1
https://doi.org/10.1158/1535-7163.22519245.v1
Autor:
Joanna Klubo-Gwiezdzinska, Vasyl Vasko, Xiaoyuan Chen, Dale Kiesewetter, Zhantong Wang, Huiyan Lu, Orit Jacobson, Craig Cochran, Corina Millo, Brianna Daley, Shilpa Thakur
Supplementary figure 8. Experimental design of mice studies. (A) Flow diagram depicts an experimental strategy for PET imaging with different SST analogs in tumor mice models. (B) Flow diagram depicts an experimental strategy for 177Lu-DOTA-EB-TATE t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c34061c3abb2c3640d3e5b986f89eb
https://doi.org/10.1158/1078-0432.22479870.v1
https://doi.org/10.1158/1078-0432.22479870.v1
Autor:
Joanna Klubo-Gwiezdzinska, Vasyl Vasko, Xiaoyuan Chen, Dale Kiesewetter, Zhantong Wang, Huiyan Lu, Orit Jacobson, Craig Cochran, Corina Millo, Brianna Daley, Shilpa Thakur
Supplemental Table 1: Analysis of immunostaining of SSTR2 in human tissue samples derived from thyroid cancer patients. Score 0-no staining, Score 1-positive staining in 50% of cells. PTC - papillary thyroid cancer, FTC - follicular thyroid cancer, P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677771ac8e6978e5979d5caff3df1234
https://doi.org/10.1158/1078-0432.22479867
https://doi.org/10.1158/1078-0432.22479867